专利号:US-2013012706-A1 优先权日:2010-03-01 标 题 :Methods and Intermediates for the Synthesis of 4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazines 发明人:HUMMERSONE MARC GEOFFERY; COUSIN DAVID 权利人:PHARMINOX LTD; HUMMERSONE MARC GEOFFERY; COUSIN DAVID 摘要:The present invention provides a compound of general formula (II), or a salt or solvate thereof: n n n n n n n n n n n n wherein n A is independently -A 1 , -A 2 , -A 3 , -A 4 , -A 5 , -A 6 , or -A 7 , wherein:n -A 1 is independently C 5-12 heteroaryl, and is optionally substituted; -A 2 is independently thioamido or substituted thioamido; -A 3 is independently imidamido, substituted imidamido, N-hydroxyimidamido, or substituted N-hydroxyimidamido; -A 4 is independently hydroxamic acid or hydroxamate; -A 5 is independently carboxamide or substituted carboxamide; -A 6 is independently aliphatic C 2-6 alkenyl, and is optionally substituted; and -A 7 is independently carboxy or C 1-4 alkyl-carboxylate;n nand its use in the synthesis of temozolomide and analogues thereof.
专利号:US-2024376065-A1 优先权日:2021-07-29 标 题:Thionolactones, processes of synthesis, uses as comonomers and for polymer functionalization and degradation 发明人:DUFILS PIERRE-EMMANUEL; PLUMMER CHRISTOPHER MARK; WILSON DAVID JAMES; GIGMES DIDIER; GUILLANEUF YOHANN 权利人:SPECIALTY OPERATIONS FRANCE; UNIV AIX MARSEILLE; CENTRE NAT RECH SCIENT 摘要:The instant invention relates to thionolactone compounds useful as comonomers to introduce weak bonds for polymer degradation or functionalization. The invention is also directed to processes for the preparation of said compounds, notably by thionation of the corresponding lactones. The invention is furthermore directed to uses of said thionolactones as comonomers, copolymers made from these comonomers, and processes for the preparation of said copolymers.
专利号:EP-3567040-B1 优先权日:2013-06-24 标 题 :Method for the preparation of intermediates useful for the synthesis of [1,2,4]-triazolo[4,3-a]pyridines
专利号:WO-2011107726-A1 优先权日:2010-03-01 标 题:Methods and intermediates for the synthesis of 4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazines
专利号:EP-3567040-A1 优先权日:2013-06-24 标题 :Method for the preparation of intermediates useful for the synthesis of [1,2,4]-triazolo[4,3-a]pyridines
专利号:EP-2542553-A1 优先权日:2010-03-01 标 题:Methods and intermediates for the synthesis of 4-oxo-3,4-dihydro-imidazo[5,1-d][1,2,3,5]tetrazines
摘要:Wicha, J., Science of Synthesis, (2009) 48, 140. 摘要:Koutentis, P. A.; Ioannidou, H. A., Science of Synthesis Knowledge Updates, (2010) 1, 307. 摘要:Koutentis, P. A.; Ioannidou, H. A., Science of Synthesis Knowledge Updates, (2010) 1, 272.