CAS: 85118-27-0; Citalopram Hydrochloride
- 英文名称Citalopram Hydrochloride
- 中文名称盐酸西酞普兰
- IUPAC名称1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile hydrochloride
- 其它别名1-[3-(Dimethylamino)Propyl]-1-(4-Fluorophenyl)-1,3-Dihydro-5-Isobenzofurancarbonitrile Hydrochloride; 1-[3-(Dimethylamino)Propyl]-1-(4-Fluorophenyl)-3H-2-Benzofuran-5-Carbonitrile,Hydrochloride; Citalopram Hydrochloride; 1-[3-(Dimethylamino)Propyl]-1-(4-Fluorophenyl)-1,3-Dihydroisobenzofuran-5-Carbonitrile Monohydrochloride; 1-(3-(Dimethylamino)Propyl)-1-(4-Fluorophenyl)-1,3-Dihydroisobenzofuran-5-Carbonitrile Monohydrochloride; Citalopram Hydrochloride Crs; Citalopram Hydrochloride Salt
- CAS编号85118-27-0
- EINECS号:285-680-9
- FDA UNII编号:4DY48G26JY
- 分子式:C20H22ClFN2O分子量:360.86
- 产品CID: 1844934
- 产品分类分析化学 → 标准品 → 药典标准品和杂志标准品
物理性质
MSDS等安全信息
欧盟法规
ECHA物质C&L通报REACH预注册合成工艺路线路线简述
海关参考信息
- 2902600000-乙苯
2905121000-正丙醇
2905130000-正丁醇
2906210000-苄醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2008119662-A1
优先权日:2004-02-16
标 题:One Spot Synthesis of Citalopram from 5-Cyanophthalide
发明人：NARAHARI BABU AMBATI; SRINIVAS GOUD VUDDAMARI; GAONKAR SANTOSH LAXMAN; MANJUNATHA SULUR G; KULKARNI ASHOK KRISHNA; KULKARNI MADHARI A
权利人:JUBILANT ORGANOSYS LIMTED
摘要:A process for one pot synthesis of citalopram is disclosed. The process comprises subjecting 5-cyano phthalide to Grignard reduction followed cyclization and followed by C-alkylation reaction to obtain citalopram without isolation and purification of any intermediates. In another embodiment, 5-cyano phthalide is subjected to sequential Grignard reactions followed by cyclization to obtain citalopram without isolation and purification of any intermediate stages.
专利号:WO-2005077927-A1
优先权日:2004-02-16
标 题:One pot synthesis of citalopram from 5-cyanophthalide
专利号:EP-1723133-A1
优先权日:2004-02-16
标 题:One pot synthesis of citalopram from 5-cyanophthalide
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1007/pl00005487
摘要:Evenden JL. The pharmacology of impulsive behaviour in rats VII: the effects of serotonergic agonists and antagonists on responding under a discrimination task using unreliable visual stimuli. Psychopharmacology (Berl). 1999 Oct;146(4):422–31. doi: 10.1007/pl00005487.
📝 需求与反馈
尽可能描述清楚需求与问题信息
