2,2,2-Trichloro-1-(2-Chloro-Phenyl)-Ethanol置于chromium(Vi) Oxide,Sodium Hydroxide,硫酸,溶剂黄146体系中,化学反应生成 2,4'-二氯二苯甲酮 参考文献:The Chemical Composition Of Technical Ddt1 标题:The Chemical Composition Of Technical Ddt1 摘要: DOI:10.1021/ja01225A058
专利号:US-4453012-A 优先权日:1982-04-22 标 题 :Process for the preparation of phenyl ketones 发明人:DESBOIS MICHEL 权利人:RHONE POULENC SPEC CHIM 摘要:A process for the preparation of phenyl ketones, characterized in that, in a first stage, a halo- or trihalomethylbenzene is reacted with a trihalomethylated aliphatic or aromatic compound in the presence of boron trifluoride in an amount such that the absolute pressure of boron trifluoride within the reaction vessel exceeds 1 bar, and in the presence of hydrofluoric acid as a solvent, and in that, in a second stage, the resultant product is hydrolyzed. The products are used as intermediates in the synthesis of compounds having a pharmaceutical or phytosanitary (e.g., herbicidal) activity.
专利号:US-4454350-A 优先权日:1982-01-21 标题:Process for the acylation of halo- or trihalomethylbenzenes 发明人:DESBOIS MICHEL 权利人:RHONE POULENC SPEC CHIM 摘要:A process for the acylation of halo- or trihalomethylbenzenes, wherein a halo- or trihalomethylbenzene is reacted with a carboxylic acid, a precursor or a derivative thereof in the presence of boron trifluoride in an amount such that the absolute pressure of the boron trifluoride within the reaction vessel exceeds 1 bar, and in the presence of hydrofluoric acid as a solvent. The resultant products are useful as intermediates in the synthesis of compounds having a phytosanitary (e.g., herbicidal) or pharmaceutical activity.
专利号:US-5780692-A 优先权日:1995-12-28 标 题:Process for producing optically active benzhydrol compounds 发明人:SAKAGUCHI MINZO; IMAI TAKASHI; MIURA TAKASHI; YAMAZAKI TETSURO 权利人:TAKASAGO PERFUMERY CO LTD 摘要:A process for producing a benzhydrol compound (II) which comprises hydrogenating a benzophenone compound (I) in the presence of a hydrogenation catalyst consisting of a transition metal complex, a base and an optically active diamine compound: (I) (II) wherein R1 to R10 each represents H, OH, C1-4 alkyl, C1-4 alkoxy, C1-4 alkanoyl, etc., R2 and R3, and R8 and R9 may form -CH=CH-CH=CH-, or any two of R1 to R9 adjacent to each other may be bonded to thereby form -OCH2O- or -(CH2)3-. By using this process, optically active benzhydrol compounds which have a high purity and are useful as, for example, intermediates in the synthesis of drugs can be produced by simple procedures.
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