📜7-羟基香豆素置于sodium Hydroxide,Palladium On Activated Charcoal体系中,化学反应生成 3-(2,4-二羟基苯)丙酸 参考文献:Bridge Et Al.,Journal Of The Chemical Society,1937,P. 1530,1534 标题:Bridge Et Al.,Journal Of The Chemical Society,1937,P. 1530,1534
专利号:US-11746364-B2 优先权日:2018-01-17 标题 :Enzymatic synthesis of kavalactones and flavokavains 发明人:PLUSKAL TOMÃ?S; Weng jing-ke 权利人:WHITEHEAD INST BIOMEDICAL RES 摘要:Disclosed are methods, compositions, proteins, nucleic acids, cells, vectors, compounds, reagents, and systems for the preparation of kavalactones, flavokavains, and kavalactone and flavokavain biosynthetic intermediates using enzymes expressed in heterologous host cells, such as microorganisms or plants, or using in vitro enzymatic reactions. This invention also provides for the expression of the enzymes by recombinant cell lines and vectors. Furthermore, the enzymes can be components of constructs such as fusion proteins. The kavalactones produced can be utilized to treat anxiety disorder, insomnia, and other psychological and neurological disorders. The flavokavains produced can be utilized to treat various cancers including colon, bladder, and breast cancers.
专利号:US-6229055-B1 优先权日:1996-04-12 标题 :Synthesis of fluorinated xanthene derivatives 发明人:KLAUBERT DIETER H; GEE KYLE R 权利人:MOLECULAR PROBES INC 摘要:Facile syntheses for fluorinated resorcinol and aminophenol derivatives are provided that yield isomer-free products in good yield. These novel methods use generally available precursors and standard laboratory reagents and equipment to reproducibly produce these synthetically useful reagents in relatively large quantities. The resulting fluorinated resorcinols and aniinophenols possess utility in the preparation of fluorinated fluorescein and rhodol dyes.
专利号:WO-2025181827-A2 优先权日:2024-02-26 标 题:Process development for substituted resorcinol production from cyclohexane-1,3-diones 发明人:DAS PRALAY; YAMINI; MEHRA PUSHKAR; KUMAR ASHISH; BAINS ROHIT; KUMAR AJAY; RAM SHANKAR; SHARMA DHARMINDER; CHAUHAN ARVIND SINGH 权利人:COUNCIL SCIENT IND RES 摘要:The invention provides a scalable and low cost process for synthesis of different high value 4-alkyl resorcinols such as 3-(2,4-dihydroxyphenyl)propanoic acid, 3-(2,4- dihydroxy-5-methylphenyl)-2-methylpropanoic acid, 4-methyl resorcinol, 4-isopropyl resorcinol and 4-hexyl resorcinol from their corresponding cyclohexane-1,3-diones. The present invention also provides a process for preparing cyclohexane-1,3-diones which is the starting materials for the synthesis of resorcinols.
专利号:US-11739354-B2 优先权日:2018-01-17 标 题 :Enzymatic synthesis of kavalactones and flavokavains
专利号:US-2022002768-A1 优先权日:2018-01-17 标题:Enzymatic synthesis of kavalactones and flavokavains
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合成参考文献
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