CAS: 486422-59-7; 4-(N,N-Dimethylsulfamoyl)Phenylboronic Acid

上下游产品

4-bromobenzenesulfonyl chloride N,N-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1-sulfonamide water 4-{6-methoxy-1-[4-(2-piperidin-1-yl-ethoxy)-phenoxy]-naphthalen-2-yl}-N,N-dimethylbenzenesulfonamide 4-(3,9-diamino-8-chloro-5,6-dihydrobenzo[f]quinazolin-1-yl)-N,N-dimethylbenzenesulfonamide N,N-dimethyl-4-(6-oxo-5,6-dihydro-benzo[c][1,8]naphthyridin-1-yl)-benzenesulfonamide 4-cyano-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazole-2-carboxylic acid (3-cyclohex-1-enyl-4'-dimethylsulfamoyl-biphenyl-4-yl)-amide

4-溴-N,N-二甲基苯磺酰胺置于sodium Periodate,1,1'-双(二苯膦基)二茂铁二氯化钯(II)二氯甲烷复合物,Potassium Acetate体系中,用 四氢呋喃,1,4-二氧六环,水 作为反应溶剂,化学反应 17.58H,反应生成 N,N-二甲基-4-硼苯磺酰胺
参考文献:Wo2020024017A5
标题:Wo2020024017A5

专利信息

专利号:US-9951062-B2
优先权日:2012-12-14
标 题 :Substituted 1 H-pyrrolo [2, 3-b] pyridine and 1 H-pyrazolo [3, 4-b] pyridine derivatives as salt inducible kinase 2 (SIK2) inhibitors
发明人：VANKAYALAPATI HARIPRASAD; YERRAMREDDY VENKATAKRISHNAREDDY; GANIPISETTY VENU BABU; TALLURI SURESHKUMAR; APPALANENI RAJENDRA P
权利人:ARRIEN PHARMACEUTICALS LLC
摘要:Compounds according to Formulas I, IA or IB: n nto pharmaceutically acceptable composition, salts thereof, their synthesis and their use as SIK2 inhibitors including such compounds and methods of using said compounds in the treatment of various diseases and/or disorders such as cancer, stroke, cardiovascular, obesity and type II diabetes.