CAS: 486-62-4; 3-(4-Methoxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-2-yl)Oxy)-4H-Chromen-4-One

该化合物是主要在各种植物中,特别是在豆类和某些药用草中发现的天然类素,是草原的甘蓝边,是指附于异索植物结构的甘蔗.Ononin展示了一系列生物活动,包括抗氧化剂,抗氟素和潜在的雌激素效应,在药理学和营养领域引起了人们的兴趣.该化合物经常被研究其潜在的健康惠益,包括其在激素调节中的作用及其在各种疾病中的影响.Ononin的特点是其溶解于有机溶剂和水中的溶解性有限,这在许多异质类中很常见.其结构特性有助于其生物活动,使其成为天然产品化学和药用应用的研究对象.

结构式图片

上下游产品

CAS号42868-84-8 formononetin te... | CAS号485-72-3 芒柄花黄素 | CAS号6919-96-6 乙酰溴葡糖 | CAS号604-69-3 β-D-葡萄糖五乙酸酯 | CAS号572-09-8 2,3,4,6-四乙酰氧基-a... | CAS号77-78-1 硫酸二甲酯 | CAS号74-88-4 碘甲烷 | CAS号485-72-3 芒柄花黄素 | CAS号2280-44-6 D-glucopyranose

合成工艺路线路线简述

    📜β-D-葡萄糖五乙酸酯置于氢溴酸,Sodium Carbonate,溶剂黄146体系中,用 甲醇 作为反应溶剂,化学反应 16.0H,反应生成 芒柄花苷
    参考文献:Tempo-Mediated Regiospecific Oxidation Of Glucosides To Glucuronides
    标题:Tempo-Mediated Regiospecific Oxidation Of Glucosides To Glucuronides
    摘要:一种tempo/次氯酸盐/溴化物氧化剂已用于将芳香和类固醇葡萄糖苷转化为相应的葡糖醛酸酯,产率非常好(48-74%).一种异黄酮葡萄糖苷未能进行此转化.
    DOI:10.1055/s-2003-42048

    海关参考信息

    专利信息


    专利号:US-2007232495-A1
    优先权日:2006-03-24
    标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
    发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

    专利号:WO-02089757-A3
    优先权日:2001-05-09
    标题 :Use of isoflavones in cosmetic or dermatological preparations
    发明人:BIERGIESSER HELGA; GALLINAT STEFAN; HERPENS ANDREAS; VENZKE KIRSTEN; SCHOENROCK UWE; STAEB FRANZ
    权利人:BEIERSDORF AG; BIERGIESSER HELGA; GALLINAT STEFAN; HERPENS ANDREAS; VENZKE KIRSTEN; SCHOENROCK UWE; STAEB FRANZ
    摘要:The use of substances selected from the following group: ipriflavone (7 -isopropoxy-isoflavone), formononetin (7 -hydroxy-4'-hethoxyisoflavonr) ononin (formononetin-7-O-β-D-glucopyranoside) 4'-isopropyl-isoflavone, mono-hydroxy-isoflavone, mono-hydroxy-dihydro-isoflavone, mono-hydroxy- tetrahydro-isoflavone, O-desmethylangolensin, dihydro-daidzein (dihydro-7,4'- dihydroxy-isoflavone), tetrahy dro-daidzein (tetrahydro- 7,4'-dihydroxy-isoflavone), dihydro-genistein (dihydro-5,7,4'-trihydroxy-isoflavone), 2-dehydro-O-desmethyl-angolensin, dehydroequol, 4-hydroxy-7-glucose-isoflavone and 5-hydroy-7,4'-dimethoxy-isoflavone, in cosmetic or dermatological preparations in the treatment and prophylaxis of symptoms of inflammatory or itchy skin conditions in sensible skin and in modificiations of DNS synthesis and/or DNS repair in skin.

    专利号:US-9238821-B2
    优先权日:2009-04-14
    标题 :Metabolic engineering for plant disease resistance
    发明人:LI WENSHENG; UPPALAPATI SRINIVASA RAO; MYSORE KIRANKUMAR S; DIXON RICHARD A; SUMNER LLOYD W
    权利人:LI WENSHENG; UPPALAPATI SRINIVASA RAO; MYSORE KIRANKUMAR S; DIXON RICHARD A; SUMNER LLOYD W; SAMUEL ROBERTS NOBLE FOUND INC
    摘要:The invention provides methods and compositions for making a dicotyledonous plant that is susceptible to Phymatotrichopsis Root Rot (PRR) more resistant to PRR, by metabolic engineering of the plant's flavonoid and isoflavonoid biosynthetic pathways. Thus, methods for increasing the synthesis and accumulation of medicarpin and/or 7,4′-dihydroxyflavone in plants such as alfalfa are provided.

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    1. Wang, T., Liu, Y., Li, X., et al. Isoflavones from green vegetable soya beans and their antimicrobial and antioxidant activities. J. Sci. Food Agric. 98(5), 2043-2047 (2018). 2. Yu, D., Duan, Y., Bao, Y., et al. Isoflavonoids from Astragalus mongholicus protect PC12 cells from toxicity induced by L-glutamate. J. Ethnopharmacol. 98(1-2), 89-94 (2005). 3. Dong, L., Yin, L., Zhang, Y., et al. Anti-inflammatory effects of ononin on lipopolysaccharide-stimulated RAW 264.7 cells. Mol. Immunol. 83, 46-51 (2017).

    合成参考文献


    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
    参考文献:10.1186/s12870-018-1291-8
    摘要:Fan W, Ge G, Liu Y, Wang W, Liu L, Jia Y. Proteomics integrated with metabolomics: analysis of the internal causes of nutrient changes in alfalfa at different growth stages. BMC Plant Biology. 2018 May 04;18(1):78. doi: 10.1186/s12870-018-1291-8.
    参考文献:10.1007/bf02994750
    摘要:Park JA, Kim HJ, Jin C, Lee KT, Lee YS. A new pterocarpan, (-)-maackiain sulfate, from the roots of Sophora subprostrata. Arch Pharm Res. 2003 Dec;26(12):1009–13. doi: 10.1007/bf02994750.
    参考文献:10.1021/jf061335o
    摘要:Liu Y, Chen HB, Zhao YY, Wang B, Zhang QY, Zhang L, Tu P. Quantification and stability studies on the flavonoids of Radix hedysari. J Agric Food Chem. 2006 Sep 06;54(18):6634–9. doi: 10.1021/jf061335o.
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