CAS: 446292-07-5; (R)-2-(2-Hydroxy-3-((4-(3-Oxomorpholino)Phenyl)Amino)Propyl)Isoindoline-1,3-Dione

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CAS号161596-47-0 (S)-(+)-N-(2,3-... | CAS号438056-69-0 4-(4-氨苯基)吗啉-3-酮 | CAS号1252018-10-2 (R)-4-[4-[(3-氯-... | CAS号1074-82-4 邻苯二甲酰亚胺钾盐 | CAS号5455-98-1 N-(2,3-环氧丙基)邻苯二甲酰亚胺 | CAS号122-98-5 N-羟乙基苯胺 | CAS号446292-04-2 4-(3-氧代-4-吗啉基)硝基苯 | CAS号29518-11-4 4-苯基-3-吗啉酮 | CAS号366789-02-8 利伐沙班 | CAS号898543-06-1 4-[4-[(5S)-5-(氨...

Potassium Phtalimide 以 乙醇,水 作为反应溶剂,化学反应 16.0H,反应生成 2-[(2R)-2-羟基-3-[[4-(3-氧代-4-吗啉)苯基]氨基]丙基]-1H-异吲哚-1,3(2H)-二酮
参考文献:一种利伐沙班中间体的制备方法
标题:一种利伐沙班中间体的制备方法
摘要:本发明提供了一种利伐沙班中间体的制备方法,包括以下步骤:(1)化合物a与化合物b在醇或醇的水溶液中反应,得到化合物c;(2)化合物c与n,N'‑羰基二咪唑反应,反应溶剂选自乙腈或丁腈,得到含化合物d的反应液,冷却析晶,得到化合物d

专利信息

专利号:WO-2013027225-A1
优先权日:2011-08-19
标 题:Processes for the preparation of 4-{4-[5(s)-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl} morpholin-3-one
发明人：MOHAN RAO DODDA; KRISHNA REDDY PINGILI; VENKAT REDDY BUTHUKURI
权利人:SYMED LABS LTD; MOHAN RAO DODDA; KRISHNA REDDY PINGILI; VENKAT REDDY BUTHUKURI
摘要:The present invention provides simple, eco-friendly, cost-effective, reproducible, robust and industrial processes for the preparation of intermediate compound 4-{4-[5(S)-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl}morpholin-3-one (II). The present invention also provides novel intermediates and their use in the synthesis of morpholinone oxazolidine derivatives.

专利号:WO-2015198259-A1
优先权日:2014-06-26
标 题:Process for the synthesis of rivaroxaban and intermediate for the production thereof
发明人：FERRARI MASSIMO; GHEZZI EMANUELE; GHEZZI MARCELLO
权利人:ERREGIERRE SPA
摘要:A process is described for the production of Rivaroxaban, a compound having the following structural formula: (I) by means of obtaining a novel intermediate of said process.

专利号:RU-2383540-C2
优先权日:2004-01-15
标 题 :Method for synthesis of 5-chloro-n-({(5s)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophenecarboxamide