CAS: 39255-32-8; Ethyl 2-Methylpentanoate

该化合物是一种属于碳酸衍生物类别的酯,由2-甲基五溴二苯醚酸和乙醇反应而成,该化合物一般是一种无色液体,有水果味,可用于调味和香味应用;乙酰2-甲基五溴二苯醚具有中度沸点,一般比水密度低;在乙醇和二乙醚等有机溶剂中溶解,但水溶性有限;该化合物的特征是其酯功能组,它有助于其再活性和挥发性;乙酰二甲基苯甲酸在水和酸或碱中可进行水解,恢复到其母酒精和酸;其应用范围超越了食品和芳香工业,因为它也可以作为溶剂或有机合成的中间体;安全数据表明,尽管接触时可能会引起刺激,但一般认为在适当处理时会具有低毒性.

结构式图片

相似化合物

97-61-0 28959-02-6 97-61-0

欧盟法规

REACH注册ECHA物质C&L通报REACH预注册

上下游产品

CAS号72184-91-9 1,1-diethoxy-2-... | CAS号1617-40-9 ethyl (E)-2-met... | CAS号64-17-5 乙醇 | CAS号97-61-0 2-甲基戊酸 | CAS号121811-29-8 2-methyl-3-oxop... | CAS号109-67-1 1-戊烯 | CAS号201230-82-2 carbon monoxide | CAS号123-15-9 2-甲基戊醛 | CAS号60988-32-1 1-(2-methyl-pen... | CAS号16957-70-3 草莓酸 | CAS号105-30-6 2-甲基-1-戊醇

合成工艺路线路线简述

    2-甲基戊醛置于sodium Hypochlorite,硫酸体系中,用 溶剂黄146,丙酮 用作溶剂,化学反应 0.75H,反应生成2-甲基戊酸乙酯
    参考文献:Sugai,Saburo; Kodama,Takashi; Akaboshi,Sanya,Chemical And Pharmaceutical Bulletin,1984,Vol. 32,# 1,P. 99-105
    标题:Sugai,Saburo; Kodama,Takashi; Akaboshi,Sanya,Chemical And Pharmaceutical Bulletin,1984,Vol. 32,# 1,P. 99-105

    海关参考信息

    专利信息


    专利号:WO-2017033128-A1
    优先权日:2015-08-25
    标题 :Biphenyl-substitued 4-amino-butyric acid derivatives and their use in the synthesis of nep inhibitors
    发明人:HOOK DAVID; KU JIE; ZHOU JIANGUANG
    权利人:NOVARTIS AG; HOOK DAVID; KU JIE; ZHOU JIANGUANG
    摘要:The invention relates to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, in particular neutral endopeptidase (NEP) inhibitors and prodrugs thereof.

    专利号:US-7329767-B2
    优先权日:2003-10-03
    标 题:Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof
    发明人:DEWIS MARK L; JOHN THUMPLASSERIL V; ECKERT MARKUS A; COLSTEE JAN HERMAN; DA COSTA NEIL C; PEI TAO
    权利人:INT FLAVORS & FRAGRANCES INC
    摘要:Described are mixtures of at least four of the alkadienamides defined according to the structure: n nwherein R represents C 1 -C 2 n-alkyl; R 1 is 2-methyl-1-propyl and R 2 is hydrogen, or R 1 and R 2 taken together is a moiety having the formulan n nwherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides ; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.

    专利号:US-8007841-B2
    优先权日:2003-10-03
    标 题 :Conjugated dienamides, methods of production thereof, compositions containing same and uses thereof
    发明人:JOHN THUMPLASSERIL V; ECKERT MARKUS A; DEWIS MARK L; COLSTEE JAN HERMAN; DA COSTA NEIL C
    权利人:INT FLAVORS & FRAGRANCES INC
    摘要:Described are mixtures of at least four of the alkadienamides defined according to the structure: n nwherein R represents C 1 -C 2 n-alkyl; R 1 is 2-methyl-1-propyl and R 2 is hydrogen, or R 1 and R 2 taken together is a moiety having the formula —(CH 2 ) n —, wherein n is 4 or 5, or compositions containing substantial concentrations of such mixtures, prepared according to novel processes: (a) extraction of a ground substantially dried fruit of one of the Piper species, Piper longum Linn or Piper peepuloides ; (b) natural product-forming synthesis; or (c) synthetic product-forming synthesis. Also described are uses of the thus-formed products for augmenting, enhancing or imparting an aroma, taste, chemesthetic effect and/or antibacterial effect in or to a consumable material and/or in the oral cavity and/or on the mammalian epidermis.

    专利号:WO-2018192923-A1
    优先权日:2017-04-18
    标题 :Alpha alkylation of aldehyde with a polycyclic olefin
    发明人:QUINTAINE JULIE; MACMILLAN DAVID W C
    权利人:FIRMENICH & CIE
    摘要:The present invention relates to the field of organic synthesis and more specifically to the alpha alkylation of an aldehyde with a polycyclic olefin followed by a ring opening step in order to provide compound of formula (I) in the form of any one of its stereoisomers or a mixture thereof and wherein R represents a hydrogen atom or C 1-8 linear alkyl group; R 1 , R 2 , R 3 and R 4 represent, when taken separately, independently of each other, a hydrogen atom or a C 1-2 linear alkyl group or a C 3-4 linear or branched alkyl group; or R 2 and R 3 , when taken together, represent a C 4-10 linear, branched or cyclic alkanediyl group and n is 1 or 2.

    专利号:WO-2024097977-A1
    优先权日:2022-11-04
    标题:Silk nanoparticle synthesis: tuning size, dispersity, and surface chemistry for drug delivery
    发明人:SHAIDANI SAWNAZ; FALCUCCI THOMAS; FOSTER OLIVIA; SAHOO JUGAL KISHORE; HASTURK ONUR; KAPLAN DAVID L; JACOBUS CHARLOTTE S
    权利人:TUFTS COLLEGE
    摘要:Methods disclosed herein relate to generating silk nanoparticles with a low polydispersity index (PDI). Methods include adding a silk solution dropwise into a volatile solvent that is miscible with water, thereby forming a precipitate-bearing solution and applying shear forces to the precipitate-bearing solution for a length of time sufficient to achieve evaporation of at least 95% of the volatile solvent, thereby producing a population of silk fibroin nanoparticles in water having a polydispersity index (PDI) of 0.35 or less, including but not limited to, a PDI of 0.330 or less, 0.325 or less, 0.315 or less, 0.310 or less, 0.30 or less, 0.275 or less, 0.250 or less, 0.225 or less, or 0.200 or less. Parameters related to silk fibroin molecular weight, silk fibroin concentration, shear force application, and temperature may all be modified to achieve silk nanoparticles of a particular size exhibiting particular PDIs.

    专利号:US-9650341-B2
    优先权日:2010-05-04
    标 题 :Process for synthesizing oxidized lactam compounds
    发明人:REMENAR JULIUS F; BLUMBERG LAURA COOK; ZEIDAN TAREK A
    权利人:ALKERMES PHARMA IRELAND LTD
    摘要:The invention provides a method for the synthesis of dehydrogenated lactam drugs of Formula I:
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    合成参考文献


    摘要:Tan, X.; Lv, H.; Zhang, X., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2017) 1, 47.
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