CAS: 166023-31-0; (R)-Tert-Butyl 3-Amino-4-Phenylbutanoate

相似化合物

138165-77-2 26250-87-3 131270-08-1

上下游产品

tert-butyl 3-amino-4-phenylbut-2-enoate phenylacetic acid 2,2-dimethyl-5-(2-phenylacetyl)-1,3-dioxane-4,6-dione

📜(3R,αr)-Tert-Butyl 3-(N-Benzyl-N-α-Methylbenzyl)Amino-4-Phenylbutanoate置于10 Wt% Pd(Oh)2 On Carbon,氢气,溶剂黄146,碳酸氢钠体系中,用 甲醇,水 用作溶剂,化学反应 72.0H,反应生成Acros网站上无此产品了
参考文献:Enantiopure 3-Amino-Substituted 1-Indanones,1-Tetralones,And 1-Benzosuberones Via Friedel-crafts Cyclisation Of ω-Aryl-β-Benzamido Acids
标题:Enantiopure 3-Amino-Substituted 1-Indanones,1-Tetralones,And 1-Benzosuberones Via Friedel-crafts Cyclisation Of ω-Aryl-β-Benzamido Acids
摘要:Conjugate Addition Of Enantiopure Lithium (R)-N-Benzyl-N-(-Methylbenzyl)Amide To A Range Of-Aryl-,-Unsaturated Esters Gives The Corresponding-Aryl--Amino Esters As Single Diastereoisomers In High Yields. Friedel-Crafts Cyclisation Of The Pendant Carbonyl Group Onto The-Aryl Ring Then Gives A Range Of 3-Amino-Substituted 1-Indanones,1-Tetralones,And 1-Benzosuberones,Representing An Efficient And Short Protocol For The Preparation Of These Benzo-Fused Carbocycles In Enantiopure Form.
Doi:10.1055/s-0034-1380675