CAS: 1466-88-2; 2-Nitrocinnamaldehyde

相似化合物

612-41-9 1013-96-3 105376-46-3

上下游产品

CAS号1504-65-0 (E)-3-(2-nitrop... | CAS号133473-26-4 3-(2-硝基-苯基)-丙醛 | CAS号108-05-4 乙酸乙烯酯 | CAS号552-89-6 邻硝基苯甲醛 | CAS号10292-65-6 1-环丙基-2-硝基苯 | CAS号6921-44-4 1-环丙基-4-硝基苯 | CAS号14371-10-9 桂皮醛 | CAS号39228-29-0 (e)-3-(2-硝基苯基)丙烯酸甲酯 | CAS号612-41-9 邻硝基肉桂酸 | CAS号635-46-1 1,2,3,4-四氢喹啉 | CAS号91-22-5 喹啉 | CAS号85753-43-1 K-252c | CAS号19005-93-7 吲哚-2-甲醛 | CAS号612-41-9 邻硝基肉桂酸 | CAS号102072-71-9 7-chloro-8-hydr... | CAS号552-89-6 邻硝基苯甲醛 | CAS号102072-72-0 6-chloro-5-hydr... | CAS号102072-74-2 sodium,7-nitro-... | CAS号133473-26-4 3-(2-硝基-苯基)-丙醛

📜O-Nitrozimtalkohol置于2,2,6,6-四甲基哌啶氧化物,Oxone,四乙基溴化铵,三乙胺体系中,用 乙腈 用作溶剂,化学反应 24.5H,以54%的收率获得邻硝基肉桂醛
参考文献:使用 Tempo-Oxone-Et4Nbr 反应物系统对烯丙醇进行串联氧化溴化
标题:使用 Tempo-Oxone-Et4Nbr 反应物系统对烯丙醇进行串联氧化溴化
摘要:烯丙醇可在与 Tempo,Oxone 和四乙基溴化铵的混合物的单一反应中直接转化为 α-溴-α,β-不饱和酮.该过程首先通过将醇氧化成酮,然后用由 Oxone 和四乙基溴化铵产生的溴对烯烃进行二溴化.然后用三乙胺淬灭反应促进消除并形成溴乙烯.芳环上给电子基团的存在导致更快的反应和更高的收率.或者,在芳环上装饰有吸电子基团的底物氧化较慢.该方法提供了一种使用操作简单的条件和稳定且易于处理的试剂来获取这些溴代烯烃的快速方法.
Doi:10.1016/j.Tetlet.2022.153994

专利信息

专利号:WO-03031376-A1
优先权日:2001-10-12
标 题 :Solid phase synthesis of substituted 1,5-benzodiazepine-2-one and 1,5-benzothiazepine-2-one
发明人：MORTON GEORGE C; SALVINO JOSEPH M; LABAUDINIERE RICHARD F; HERPIN TIMOTHY F
权利人:AVENTIS PHARMA INC; MORTON GEORGE C; SALVINO JOSEPH M; LABAUDINIERE RICHARD F; HERPIN TIMOTHY F
摘要:A solid phase synthetic method for making substituted 1,5-benzodiazepine-2-one or 1,5-benzothiazepine-2-one. The method is useful for synthesis of large numbers of compounds through automated parallel synthesis or combinatorial library generation and is thus important to rapid discovery or new therapeutic agents containing the base structure of 1,5-benzodiazepine-2-one or 1,5-benzothiazepine-2-one.

专利号:US-11999757-B2
优先权日:2017-11-01
标 题:Synthesis of boronate ester derivatives and uses thereof
发明人：BOYER SERGE HENRI; HECKER SCOTT J; VERZIJL GERARDUS K M; HERMSEN PETRUS J
权利人:MELINTA SUBSIDIARY CORP
摘要:Disclosed herein are methods for the preparation of boronate derivatives in the synthesis of antimicrobial compounds and uses thereof. Disclosed herein includes method of making a compound of Formula (B) by reducing the ketone group of the keto-ester compound of Formula (A), and the reduction can be performed using a Ruthenium based catalyst system or using an alcohol dehydrogenase bioreduction system.

专利号:WO-2015198349-A1
优先权日:2014-06-25
标 题 :A one pot synthesis of 3-substituted quinoline carboxylates and its derivatives
发明人：GADAKH SUNITA KHANDERAO; SUDALAI ARUMUGAM
权利人:COUNCIL SCIENT IND RES
摘要:The present invention provides a one pot, simple, cost effective and industrially feasible catalytic synthesis of quinolines or substituted quinolines from anilines with yield >80% yield. The present invention also discloses a process for the synthesis of oxolinic acid using quinolines with yield > 45%.

专利号:US-7138526-B1
优先权日:1999-06-15
标 题 :Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives
发明人：HERPIN TIMOTHY F; MORTON GEORGE C; SALVINO JOSEPH M
权利人:AVENTIS PHARMA INC
摘要:A method for the solid phase synthesis of N,N-disubstituted diazacycloalkylcarboxy derivatives of general formula (I) and (II) is claimed. Examples include piperazine-2-carboxamide. The method is applicable to the synthesis or large combinatorial libraries

专利号:US-10669292-B2
优先权日:2014-05-05
标 题 :Synthesis of boronate salts and uses thereof
发明人：HECKER SCOTT; BOYER SERGE
权利人:REMPEX PHARMACEUTICALS INC
摘要:Disclosed herein are boronate intermediates in the synthesis of antimicrobial compounds and the use and preparation thereof. Some embodiments relate to crystalline boronate salt derivatives and their use in the synthesis of therapeutic compounds.

专利号:US-6127515-A
优先权日:1997-11-18
标 题:Functionalized resin for the synthesis of amides and peptides
发明人：MANFRE FRANCO; VANASSE BENOIT J; LABAUDINIERE RICHARD F; MORTON GEORGE C
权利人:AVENTIS PHARM PROD INC
摘要:This invention is directed to a functionalized amino resin of formula ##STR1## wherein S is a solid support; R is H or alkyl; A is ##STR2## Y is OH or OCOR 1 ; and R 1 is aliphatic or aromatic which is useful for the solid phase synthesis of amides, peptides and hydroxamic acids.