CAS: 139-33-3; Edta Disodium Salt

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6381-92-6 13235-36-4 139-89-9

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CAS号4865-84-3 1,2-苯并异恶唑-3-乙酸 | CAS号124-38-9 二氧化碳 | CAS号497-19-8 纯碱 | CAS号60-00-4 乙二胺四乙酸 | CAS号17396-35-9 四氢噻喃-4-酮1,1-二氧化物 | CAS号688-57-3 N-(羧甲基)-N-2-(羧甲... | CAS号50-00-0 甲醛 | CAS号64-18-6 甲酸

专利信息

专利号:WO-2025125181-A1
优先权日:2023-12-14
标题:Green hydrogen, synthesis gas with a reduced nitrogen content, and flue gas for the synthesis of ammonia and urea
发明人：GORVAL EVGENI
权利人:THYSSENKRUPP UHDE GMBH; THYSSENKRUPP AG
摘要:The invention relates to the synthesis of urea from ammonia and carbon dioxide, wherein the hydrogen required for ammonia synthesis is obtained both by steam reforming of feed natural gas (grey hydrogen) and by electrolysis of water using electricity from renewable energy sources (green hydrogen). As the proportion of green hydrogen increases, the amount of carbon dioxide formed in the synthesis gas during steam reforming is no longer sufficient for the synthesis of urea. Therefore, flue gas, which is formed during the combustion of a fuel gas composed of fuel natural gas and combustion air and which also contains carbon dioxide, is additionally used. The oxygen formed during the electrolysis of water is introduced into the flue gas, and the modified flue gas is fed to a secondary reformer; and/or the fuel natural gas is combusted together with combustion air and the oxygen formed during electrolysis. Excess nitrogen is preferably separated from the synthesis gas before it is used for the synthesis of ammonia.

专利号:WO-2025125180-A1
优先权日:2023-12-14
标 题 :Green hydrogen, synthesis gas, and flue gas with a reduced nitrogen content for the synthesis of ammonia and urea
发明人：GORVAL EVGENI
权利人:THYSSENKRUPP UHDE GMBH; THYSSENKRUPP AG
摘要:The invention relates to the synthesis of urea from ammonia and carbon dioxide, wherein the hydrogen required for ammonia synthesis is obtained both by steam reforming of feed natural gas (grey hydrogen) and by electrolysis of water using electricity from renewable energy sources (green hydrogen). As the proportion of green hydrogen increases, the amount of carbon dioxide formed in the synthesis gas during steam reforming is no longer sufficient for the synthesis of urea. Therefore, flue gas, which is formed during the firing of the steam reformer and also contains carbon dioxide, is additionally used. After reducing the nitrogen content, the flue gas is fed into the reforming process. The carbon dioxide from the synthesis gas and the flue gas is combined, separated using conventional carbon dioxide scrubbing, and used for the synthesis of urea.

专利号:US-12383499-B2
优先权日:2018-01-01
标题:Scale up synthesis of silicasome nanocarriers
发明人：NEL ANDRE E; MENG HUAN; LIU XIANGSHENG
权利人:UNIV CALIFORNIA
摘要:In order to facilitate the approval and commercialization of silicasome drug delivery systems (e.g. irinotecan silicasomes) it is necessary to scale up synthesis of the drug-loaded silicasomes. In this regard, it was discovered that the synthesis protocols used for laboratory synthesis of drug-loaded silicasomes (e.g., 500 mg/batch) do not scale to large scale silicasome production, because the resulting products were too heterogeneous for use as pharmaceuticals. Accordingly, new methods are provided herein that effectively afford the large-scale production of mesoporous silica nanoparticles (MSNPs) and lipid bilayer coated MSNPs (silicasomes).

专利号:US-6451543-B1
优先权日:1998-08-31
标题:Lipid matrix-assisted chemical ligation and synthesis of membrane polypeptides
发明人：KOCHENDOERFER GERD G; HUNTER CHRISTIE L; KENT STEPHEN B H; BOTTI PAOLO
权利人:GRYPHON SCIENCES
摘要:The present invention relates to methods and compositions for lipid matrix-assisted chemical ligation and synthesis of membrane polypeptides that are incorporated in a lipid matrix. The invention is exemplified in production of a prefolded membrane polypeptide embedded within a lipid matrix via stepwise chemoselective chemical ligation of unprotected peptide segments, where at least one peptide segment is embedded in a lipid matrix. Any chemoselective reaction chemistry amenable for ligation of unprotected peptide segments can be employed. Suitable lipid matrices include liposomes, micelles, cell membrane patches and optically isotropic cubic lipidic phase matrices. Prefolded synthetic and semi-synthetic membrane polypeptides synthesized according to the methods and compositions of the invention also permit site-specific incorporation of one or more detectable moieties, such as a chromophore, which can be conveniently introduced during synthesis. The methods and compositions of the invention have multiple uses. For example, they can be used to assay ligand binding to membrane polypeptides and domains comprising a receptor, and thus are extremely useful for structure/function studies, drug screening/selection/design, and diagnostics and the like, including high-throughput applications. The methods and compositions of the invention are particularly suited for FRET analyses of previously inaccessible membrane polypeptides.

专利号:US-7435861-B2
优先权日:2005-04-29
标 题 :Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates
发明人：LOCKWOOD SAMUEL F; TANG PENG CHO; NADOLSKI GEOFF; JACKSON HENRY L; FANG ZHIQIANG; DU YISHU; YANG MIN; GEISS WILLIAM; WILLIAMS RICHARD; BURDICK DAVID
权利人:CARDAX PHARMACEUTICALS INC
摘要:A method for synthesizing intermediates for use in the synthesis of carotenoid synthetic intermediates, carotenoid analogs, and/or carotenoid derivatives. The carotenoid analog, derivative, or intermediate may be administered to a subject for the inhibition and/or amelioration of any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In some embodiments, the invention may include methods for synthesizing chemical compounds including an analog or derivative of a carotenoid. Carotenoid analogs or derivatives may include acyclic end groups. In some embodiments, a carotenoid analog or derivative may include at least one substituent. The substituent may enhance the solubility of the carotenoid analog or derivative such that the carotenoid analog or derivative at least partially dissolves in water.

专利号:US-12221452-B2
优先权日:2017-10-04
标题:Synthesis of cantharidin
发明人：DAVIDSON MATTHEW GENE; EKLOV BRIAN MATTHEW; WUTS PETER; LOERTSCHER BRAD MELVIN; SCHOW STEVEN R
权利人:VERRICA PHARMACEUTICALS INC
摘要:The invention provides synthetic methods for the preparation of cantharidin and analogs thereof. In one aspect, the invention provides an improved Diels-Alder cycloaddition to generate a key intermediate en route to cantharidin and analogs thereof. In certain embodiments, the new Diels-Alder reaction involves reacting Compound (2) in the presence of furan, and in the absence of acid or increased pressure, in an aprotic polar solvent with slight warming, to yield Compound (1) in favorable yield and exo-endo ratio. In another aspect, the invention also provides a new Diels-Alder reaction between compounds of Formula (III) and furan to yield compounds of Formula (IV), which can then be transformed into cantharidin or analogs thereof. In yet another aspect, the invention describes a new palladium-mediated carbonylation providing another key intermediate en route to cantharidin and analogs thereof. In addition to synthetic methods, present invention also provides compounds (i.e., intermediates) useful in the synthesis of cantharidin and analogs thereof. Compounds provided herein may have biological activity, and therefore may be used in the treatment of diseases or conditions (e.g., infectious diseases and skin conditions).