CAS: 624-76-0; 2-Iodoethanol

相似化合物

101166-65-8 4296-15-5 54555-84-9

上下游产品

ethylene glycol 2-chloro-ethanol ethene 2-hydroxyethyl radical iodoethyl carbamate (-)-(2R)-2-amino-3-(2-hydroxyethylsulfanyl)propanoic acid allophanic acid-(2-iodo-ethyl ester) myristic acid-(2-iodo-ethyl ester)

2-氯乙醇置于sodium Iodide体系中,用 丙酮 作为反应溶剂,化学反应生成 2-碘乙醇
参考文献:有效合成某些5-取代的2'-脱氧尿苷3',5'-环单磷酸对烷基(芳烷基)酯.带有轴向甲氧基的5-Iodo-2'-脱氧尿苷3',5'-环单磷酸对甲基酯的晶体和分子结构
标题:有效合成某些5-取代的2'-脱氧尿苷3',5'-环单磷酸对烷基(芳烷基)酯.带有轴向甲氧基的5-Iodo-2'-脱氧尿苷3',5'-环单磷酸对甲基酯的晶体和分子结构
摘要:由母体环状单磷酸酯的银盐和烷基(芳烷基)碘化物的银盐制备了一些5-烷基-和5-卤代-2'-脱氧尿苷3',5'-环状单磷酸po-烷基(芳烷基)酯.非对映体磷酸三酯已通过光谱法表征.已经确定了具有轴向甲氧基的5-碘-2'-脱氧尿苷3',5'-环单磷酸po-甲酯的晶体和分子结构.与文献先前的权利要求相反,我们无法从camp银盐与烷基碘的反应中获得所需的三酯.
DOI:10.1016/0040-4020(84)80024-1

专利信息

专利号:US-12441721-B2
优先权日:2020-07-21
标 题 :Synthesis of heterocyclic compounds from carboxamide and carboxamide derivatives with haloalkanols
发明人：KARPOORMATH RAJSHEKHAR; SAYYAD NISAR
权利人:UNIV OF KWAZULU NATAL
摘要:The invention provides for methods for the synthesis of various compounds through reaction of carboxamide, or carboxamide derivatives, with various substituted or unsubstituted haloalkanols in a one-step, single vessel, reaction mechanism. Preferably, but not exclusively, the reaction proceeds in the absence of any solvents, catalyst, base, or any further reagents.

专利号:WO-2011101864-A1
优先权日:2010-02-17
标题 :Novel process for the synthesis of phenoxyethyl derivatives
发明人：JAIN RAJESH; JAGDEESHWAR RAO R; MAHENDER RAO SIRIPRAGADA
权利人:PANACEA BIOTEC LTD; JAIN RAJESH; JAGDEESHWAR RAO R; MAHENDER RAO SIRIPRAGADA
摘要:The present invention provides an improved process for the synthesis of 2-[2- (2,2,2-trifluoroethoxy)phenoxy]ethanol intermediate, its derivatives and/or its pharmaceutically acceptable salts, useful in the synthesis of α-1 adrenoceptor blockers such as silodosin.

专利号:US-5436143-A
优先权日:1992-12-23
标题:Method for enzymatic synthesis of oligonucleotides
发明人：HYMAN EDWARD D
摘要:Enzymatic synthesis of oligonucleotides may be performed in a single vessel without intermediate purification, by the steps of: n (a) combining a nucleotide primer sequence and a blocked nucleotide in the presence of a chain extending enzyme whereby a reaction mixture is formed containing the blocked nucleotide coupled to the nucleotide primer sequence at its 3' end; n (b) inactivating the chain extending enzyme; n (c) removing the blocking group from the primer-blocked nucleotide to form a primer-nucleotide product; and converting any unreacted blocked nucleotide to an unreactive form which is substantially less active as a substrate for the chain extending enzyme than the blocked nucleotide.

专利号:US-2013184465-A1
优先权日:2010-09-30
标 题:Process for the synthesis of thio-triazolo-group containing compounds
发明人：DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL
权利人:DOCHNAHL MAXIMILIAN; KEIL MICHAEL; GEBHARDT JOACHIM; VOGELBACHER UWE JOSEF; RACK MICHAEL; BASF SE
摘要:The present invention relates to a process using specific magnesium reagents for providing thio-triazolo group-containing compounds and for the synthesis of precursors therefor. The invention furthermore relates to intermediates and to their preparation.

专利号:US-9346851-B2
优先权日:2008-02-22
标 题 :Chemical modification of proteins
发明人：BERNARDES GONCALO; CHALKER JUSTIN; DAVIS BENJAMIN
权利人:BERNARDES GONCALO; CHALKER JUSTIN; DAVIS BENJAMIN; RP SCHERER TECHNOLOGIES LLC
摘要:The invention relates to methods for selectively converting a cysteine residue in a peptide or protein to the dehydroalanine (Dha) residue. The method also works on selenocysteine and substituted cysteine and selenocysteine residues, resulting in the Dha residue which may be converted to any natural or unnatural amino acid residue desired without the alteration of the remainder of the peptide or protein. The invention also allows ligation of a desired peptide at any point rather than at a point where there should be a naturally occurring cysteine, thereby allowing native chemical ligation to be used in the synthesis of peptides that do not contain cysteine. The methodology allows for the synthesis of very large peptides.

专利号:US-9975832-B2
优先权日:2014-12-29
标题:Process for the preparation of ospemifene and fispemifene
发明人：CRISTIANO TANIA; ALPEGIANI MARCO
权利人:OLON SPA
摘要:Disclosed is a process for the synthesis of the active ingredients ospemifene and fispemifene which comprises reacting phenol 4 with an alkylating agent X—CH 2 CH 2 —Y of formula 7, wherein X is a leaving group and Y is the —(OCH 2 CH 2 ) n OH group wherein n is zero or 1; or X and Y, taken together, represent an oxygen atom; to give ospemifene or fispemifene of formula 8.