CAS: 55234-58-7; 3-Aminopicolinaldehyde

相似化合物

116026-99-4 1462-86-8 27507-15-9

上下游产品

3-amino-2-hydroxy-methylpyridine ethyl 3-aminopyridine-2-carboxylate 3-nitropyridine-2-carboxaldehyde 2-Chloro-3-nitropyridine methyl (2-(2-(methylsulfonyl)phenyl)-1,5-naphthyridin-3-yl)methanol 2-(1-(2-(2-(methylsulfonyl)phenyl)-1,5-naphthyridin-3-yl)ethyl)isoindoline-1,3-dione N-(1-(2-(3-fluorophenyl)-1,5-naphthyridin-3-yl)ethyl)-9H-purin-6-amine 2-(3-fluorophenyl)-1,5-naphthyridine-3-carbaldehyde

📜3-氨基吡啶-2-甲酸乙酯置于manganese(Iv) Oxide,Lithium Aluminium Tetrahydride体系中,用 四氢呋喃,氯仿 作为反应溶剂,化学反应 25.0H,反应生成 3-氨基吡啶-2-醛
参考文献:某些苯并[B] [1,8]和[1,5]萘啶的合成
标题:某些苯并[B] [1,8]和[1,5]萘啶的合成
摘要:通过将2-甲基环己酮环合到合适的氨基吡啶甲醛上,然后芳构化和氧化甲基,可以制备出一系列标题化合物的羧酸衍生物,作为潜在的抗肿瘤化合物的前体.
DOI:10.1002/jhet.5570290525

专利信息

专利号:US-8598153-B2
优先权日:2006-09-22
标题 :Method of treatment using fatty acid synthesis inhibitors
发明人：SINGH SHEO B; TOTA MICHAEL R; WANG JUN
权利人:SINGH SHEO B; TOTA MICHAEL R; WANG JUN; MERCK SHARP & DOHME
摘要:The present invention relates to natural products that possess fatty acid synthesis inhibitor activity and can be used to treat and prevent diseases such as obesity, cancer, diabetes, fungal infections, Mycobacterium tuberculosis infections, malarial infections and other apicomplexan protozoal diseases.

专利号:WO-2008022467-A1
优先权日:2006-08-25
标 题 :2-substituted azain doles and 2 substituted thienopyrroles, their precursors and novel processes for the preparation thereof
发明人：LAUTENS MARK; YUEN JOSEPHINE; FANG YUANQING
权利人:LAUTENS MARK; YUEN JOSEPHINE; FANG YUANQING
摘要:The present invention relates generally to processes for the chemical synthesis of azaindole and thienopyrrole compounds, in particular azaindole and thienopyrrole compounds that are substituted at the 2-position of the azaindole or thienopyrrole ring, and optionally at additional locations of the azaindole or thienopyrrole ring such as the 1- and/or 3-position, compounds prepared by such processes, and synthetic precursors of such processes. More particularly, the present invention relates to the preparation of 2- substituted azaindoles from an ortho-gem-dihalovinylaminopyridine or from an ortho- gem-dihalovinylaminopyridine N-oxide compound and an organoboron reagent using a palladium metal pre-catalyst, base and a ligand. The present invention also relates to the preparation of 2-substituted thienopyrroles from an ortho-gem-dihalovinylthiophene compound and an organoboron reagent using a palladium metal pre-catalyst, base and a ligand. The present invention also relates to processes for the production of ortho-gem- dihalovinylaminopyridines which are useful as starting materials in the production of 2- substituted azaindoles, and novel compounds prepared by the processes. The present invention also relates to processes for the production of ortho-gem-dihalovinylthiophenes which are useful as starting materials in the production of 2-substituted thienopyrroles, and novel compounds prepared by the processes. Formulae (V) and (VII).

专利号:EP-1501503-B1
优先权日:2002-05-09
标 题:Substantially pure solid form of the enol tautomer of 3-indolypyruvic acid for use in the treatment of central nervous system disturbances
发明人：POLITI VINCENZO; SELLA ANTONIO; BARTOLINI BARBARA; MARGONELLI ANDREA; SOMMA FRANCESCA; CORNIELLO CRISTINA
权利人:POLIFARMA SPA
摘要:The enol tautomer of 3-indolylpyruvic acid in stable and pure form, as well as alkali and alkali-earth salts thereof are produced by synthesis process. The enol tautomer comprises only the geometric isomer (Z) and it is the only one tautomeric form having relevant pharmacological effects. The compounds obtained exhibited relevant biochemical and pharmacological properties in pathological situations like anxiety, depression, behaviour disturbances, neuronal degenerations, etc.

专利号:RU-2198875-C2
优先权日:1997-05-15
标 题:Methods of synthesis of pyridine-2-carboxaldehyde thiosemicarbazones and intermediate pyridine-2-carboxaldehydes

专利号:CN-119638694-A
优先权日:2018-11-16
标 题 :Improved synthesis of key intermediates for KRAS G12C inhibitor compounds

专利号:CN-114728960-B
优先权日:2019-11-14
标 题:Improved synthesis of KRAS G12C inhibitor compounds