CAS: 53249-34-6; 2-((Tert-Butoxycarbonyl)Amino)-2-(4-Hydroxyphenyl)Acetic Acid

上下游产品

CAS号24424-99-5 二碳酸二叔丁酯 | CAS号122-87-2 N-(4-羟苯基)苷氨酸 | CAS号51300-90-4 tert-butyl hydr... | CAS号6324-01-2 (1)-4-Hydroxyph... | CAS号1070-19-5 Carbonazidic ac... | CAS号7732-18-5 水 | CAS号870-46-2 肼基甲酸叔丁酯

📜肼基甲酸叔丁酯置于碳酸氢钠,Sodium Nitrite体系中,用 四氢呋喃,1,4-二氧六环,水,溶剂黄146 作为反应溶剂,化学反应 70.0H,反应生成 N-Boc-Dl-4-羟基苯甘氨酸
参考文献:(+/-)-3-氨基心酸的新型合成
标题:(+/-)-3-氨基心酸的新型合成
摘要:(+/-)-3-Aminonocardicinicic Acid(3-Ana,2)是合成诺卡霉素a(1)和其他生物活性类似物的重要材料,已通过一种新的合成方法合成了诺卡汀a(1)和其他生物活性类似物. α-亚甲基-β-内酰胺.
DOI:10.1016/s0040-4020(01)96430-0

专利信息

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-2010022772-A1
优先权日:2003-06-03
标 题:Process for the synthesis of biaryl oxazolidnones

专利号:US-8324398-B2
优先权日:2003-06-03
标 题:Process for the synthesis of biaryl oxazolidinones

专利号:US-6992097-B2
优先权日:1998-08-18
标 题 :Growth hormone secretagogues
发明人：HAUSER KENNETH LEE; DODGE JEFFREY ALAN; HEIMAN MARK LOUIS; JONES SCOTT ALAN; ALT CHARLES ARTHUR; BRYANT HENRY UHLMAN; COHEN JEFFREY DANIEL; COPP JAMES DENSMORE; FAHEY KENNAN JOSEPH; GRITTON WILLIAM HARLAN; JUNGHEIM LOUIS NICKOLAUS; KENNEDY JOSEPH HENRY; LUGAR III CHARLES WILLIS; MUEHL BRIAN STEPHEN; PALKOWITZ ALAN DAVID; RATZ ANDREW MICHAEL; RHODES GARY ANTHONY; ROBEY ROGER LEWIS; SEYLER DAVID EDWARD; SHEPHERD TIMOTHY ALAN; THRASHER KENNETH JEFF; TRANKLE WILLIAM GEORGE
权利人:LILLY CO ELI
摘要:This invention relates to novel compounds which are useful in the modulation of endogenous growth hormone levels in a mammal. The invention further relates to novel intermediates for use in the synthesis of said compounds, as well as novel processes employed in these syntheses. Also included are methods of treating a mammal which include the administration of said compounds.