CAS: 493-75-4; Bialamicol
- 英文名称Bialamicol
- 中文名称比拉米可
- IUPAC名称3,3'-diallyl-5,5'-bis((diethylamino)methyl)-[1,1'-biphenyl]-4,4'-diol
- 其它别名3,3-Diallyl-5,5-Bis(Diethylaminomethyl)Biphenyl-4,4-Diol; 5,5'-Bis(Diethylaminomethyl)-3,3'-Diallyl-1,1'-Biphenyl-4,4'-Diol; 5,5'-Diallyl-3,3'-Bis[(Diethylamino)Methyl]-4,4'-Dihydroxybiphenyl; 2-(Diethylaminomethyl)-4-[3-(Diethylaminomethyl)-4-Hydroxy-5-Prop-2-Enyl-Phenyl]-6-Prop-2-Enyl-Phenol; 2-(Diethylaminomethyl)-4-[3-(Diethylaminomethyl)-4-Hydroxy-5-Prop-2-Enylphenyl]-6-Prop-2-Enylphenol; 2-Allyl-4-[3-Allyl-5-(Diethylaminomethyl)-4-Hydroxy-Phenyl]-6-(Diethylaminomethyl)Phenol; Bialamicol; [1,1'-Biphenyl]-4,4'-Diol, 3,3'-Bis[(Diethylamino)Methyl]-5,5'-Di-2-Propen-1-Yl-
- CAS编号493-75-4
- MFCD编号:MFCD00864649
- FDA UNII编号:TA5NM093QJ
- 分子式:C28H40N2O2分子量:436.64
- 产品CID: 1481082
- 产品分类原料药 → 抗寄生虫病药 → 抗阿米巴病及抗滴虫病药
物理性质
MSDS等安全信息
上下游产品
CAS号50-00-0 甲醛 | CAS号6942-01-4 2,2-二烯丙基-4,4'-联苯酚 | CAS号109-89-7 二乙胺 | CAS号92-88-6 4,4'-二羟基联苯 | CAS号41481-62-3 4,4'-bis(allyly...合成工艺路线路线简述
📜4,4'-二羟基联苯置于potassium Carbonate,N,N-二乙基苯胺体系中,用 乙醇,丙酮 作为反应溶剂,化学反应 52.0H,反应生成 比拉米可
参考文献:Halogenated Analogs Of The Antimalarial Bialamicol
标题:Halogenated Analogs Of The Antimalarial Bialamicol
摘要:为了提高抗疟药比亚拉米醇的药理活性,人们成功地在烯丙基侧链的 2 位引入了取代基.2-Fluoroallyl Bromide(2-氟烯丙基溴)是一种多用途的 C3F 构建模块,它是首次被描述.
DOI:10.1055/s-1996-4262
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2902600000-乙苯
2907121100-间甲酚 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: BURCKHALTER JH, LEIB RI, CHOUGH YS, TIETZ RF. ANTIAMEBIC AGENTS. VI. ANALOGS OF BIALAMICOL AND RELATED QUINOLINOLS. J Med Chem. 1963 Jan;6:89-90. doi: 10.1021/jm00337a025.
合成参考文献
参考文献:10.1126/science.1211936
摘要:Meister S, Plouffe DM, Kuhen KL, Bonamy GMC, Wu T, Barnes SW, Bopp SE, Borboa R, Bright AT, Che J, Cohen S, Dharia NV, Gagaring K, Gettayacamin M, Gordon P, Groessl T, Kato N, Lee MCS, McNamara CW, Fidock DA, Nagle A, Nam T, Richmond W, Roland J, Rottmann M, Zhou B, Froissard P, Glynne RJ, Mazier D, Sattabongkot J, Schultz PG, Tuntland T, Walker JR, Zhou Y, Chatterjee A, Diagana TT, Winzeler EA. Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery. Science. 2011 Dec 09;334(6061):1372–7. doi: 10.1126/science.1211936.
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