CAS: 3355-28-0; 1-Bromo-2-Butyne

相似化合物

2219-66-1 16400-32-1 4245-89-0

上下游产品

CAS号764-01-2 2-丁炔-1-醇 | CAS号7789-60-8 三溴化磷 | CAS号113984-38-6 but-2-ynyl N,N'... | CAS号2768-41-4 1-methoxybut-2-yne | CAS号53799-85-2 N-[dimethylamin... | CAS号74-88-4 碘甲烷 | CAS号105643-77-4 1-azidobut-2-yne | CAS号108-94-1 环己酮 | CAS号22509-75-7 Benzene,1-(2-bu... | CAS号188025-73-2 dimethyl 2-but-... | CAS号128-09-6 N-氯代丁二酰亚胺 | CAS号75-98-9 三甲基乙酸 | CAS号110-54-3 正己烷 | CAS号2520-99-2 N-benzyl-N-meth... | CAS号764-35-2 2-已炔 | CAS号764-73-8 2,6-辛二炔

Tetra-N-Methyl-Phosphorodiamidic Acid But-2-Ynyl Ester置于三溴化磷体系中,用 乙醚 用作溶剂,化学反应 4.0H,反应生成1-溴-2-丁炔
参考文献:Synthesis Of 2-Alkynyl Tetramethylphosphorodiamidates; A New Route To 1-Bromo-2-Alkynes
标题:Synthesis Of 2-Alkynyl Tetramethylphosphorodiamidates; A New Route To 1-Bromo-2-Alkynes
摘要:
Doi:10.1055/s-1974-23426

专利信息

专利号:US-9556140-B2
优先权日:2013-01-26
标 题 :Approach for synthesis of catechins
发明人：DUGAR SUNDEEP; MAHAJAN DINESH; RAI KUMAR SANTOSH; TRIPATHI VINAYAK; PATIL ISHWAR RAKESH
权利人:SPHAERA PHARMA PRIVATE LTD
摘要:A process for synthesis of enatiomerically pure or enatiomerically enriched or racemic mixture of (+ and/or −) epicatechin and its intermediates, comprising the steps of: (i) obtaining penta-protected quercetin; (ii) reducing the penta-protected quercetin obtained from step (i); (iii) optionally deprotecting the compound of step (ii); (iv) reducing the compound obtained from step (ii) or step (iii) in the presence of a chiral/achiral reducing agent to obtain a chiral intermediate; (v) deprotecting and/or hydrogenation of the chiral intermediate obtained from step (iv) to obtain (−)-epicatechin; (vi) optionally simultaneously deprotecting and by drogenation of the compound obtained from step (ii) to obtain racemic epicatechin.

专利号:US-6455680-B1
优先权日:2000-12-21
标 题 :Methods utilizing aryl thioimines in synthesis of erythromycin derivatives
发明人：LUKIN KIRILL A
权利人:ABBOTT LAB
摘要:An efficient deoximation technique for use in synthesis of erythromycin derivatives, involving aryl thioimine intermediates is disclosed. The aryl thioimine intermediates can be utilized in a method for protecting a ketone of a ketone-containing erythromycin derivative as a thioimine; a method for deoximating an oxime-containing erythromycin derivative, or a method for preparing a 6-O-alkyl erythromycin derivative. Presently preferred erythromycin derivatives have a C-9 oxime or a C-9 ketone.

专利号:US-12275733-B2
优先权日:2016-11-07
标 题:Substituted pyrido[3,4-b]indoles for the treatment of cartilage disorders
发明人：GRETZKE DIRK; RITZELER OLAF; HEINELT UWE; WEHNER VOLKMAR; SCHMIDT FRIEDEMANN
权利人:SANOFI SA
摘要:The present invention relates to 8-aryl-substituted and 8-heteroaryl-substituted 9H-pyrido[3,4-b]indoles of the formula (I), in which A, E, G, R1 to R6 and R10 are as defined in the claims, which stimulate chondrogenesis and cartilage matrix synthesis and can be used in the treatment of cartilage disorders and conditions in which a regeneration of damaged cartilage is desired, for example joint diseases such as osteoarthritis. The invention furthermore relates to processes for the synthesis of the compounds of the formula (I), their use as pharmaceuticals, and pharmaceutical compositions comprising them.

专利号:US-9428482-B2
优先权日:2011-01-27
标 题 :Process for synthesis of polyphenols
发明人：DUGAR SUNDEEP; MAHAJAN DINESH; PANTELIS PETER GIANNOUSIS; SINGH VIJAY; KAPOOR KAMAL KISHORE
权利人:DUGAR SUNDEEP; MAHAJAN DINESH; PANTELIS PETER GIANNOUSIS; SINGH VIJAY; KAPOOR KAMAL KISHORE; SPHAERA PHARMA PTE LTD
摘要:The present invention provides synthetic processes for preparing racemic and/or optically pure epicatechin, epigallocatechin and related polyphenols as such or as their variously functionalized derivatives. A principle objective of the disclosure is to provide a new and useful method of synthesis to obtain polyphenols in isomerically pure and/or racemic forms.

专利号:US-8030496-B2
优先权日:2005-02-17
标 题:Intermediate compound for synthesis of viridiofungin a derivative
发明人：KATO TATSUYA; KIMURA NOBUAKI; MIZUTANI AKEMI; MAKINO TOSHIHIKO; KAWASAKI KENICHI; FUKUDA HIROSHI; KOMIYAMA SUSUMU; TSUKUDA TAKUO
权利人:CHUGAI PHARMACEUTICAL CO LTD
摘要:A method whereby a compound having HCV replication inhibitory activity and desired optical activity can be synthesized selectively and at high yield in a small number of steps by using a compound having a specific chiral auxiliary as a starting compound is provided. n A compound represented by the formula (1-8): n n n n n n n n n n n n wherein Y represents a group represented by the following formula: n n n n n n n n n n n n n n n n Q represents a protected carbonyl group; D represents —(CH 2 ) m —R′, etc.; and n represents an integer of 0 to 10.

专利号:US-2002156320-A1
优先权日:2000-01-13
标 题 :Enantioselective synthesis of valproic acid analogues
发明人：NAU HEINZ
摘要:This invention employs camphorsultam as a chiral recoverable auxiliary to provide a new method for manufacturing valproic acid and valproic acid amides that facilitates the enantioselective or diasteroselective production of valproic acid analogs on a larger scale.