CAS: 254-79-5; 1,5-Naphthyridine

该化合物是一种环环环有机化合物,在1和5个位置上有一个装有两个氮原子的双环结构,由于药用化学和材料科学的僵硬,平板框架和缺乏电子特性,该化合物是药用化学和材料科学的多用途构件,其结构特性使其对合成药品,金属协调用离心机和光电子材料具有价值.该化合物表现出很强的共聚性,提高了其在需要充电运输或荧光的应用程序中的实用性.该化合物的再活动允许选择性的功能化,能够根据具体的研究或工业需要进行量身定制的修改.可提供高纯度的等级,以确保合成应用的一致性.

结构式图片

相似化合物

7675-32-3 1228666-28-1 7689-62-5

欧盟法规

ECHA物质C&L通报

上下游产品

pyridin-3-ylamine glycerol 3-(3-(2-phenylimidazol-1-yl)propyl)-1,2,4-triazine 4-(2-phenyl-1H-imidazol-1-yl)butanenitrile (1)-oxide1,5-naphthyridine N-(1)-oxide 1,5-naphthyridine 1,5-dioxide 2-amino-1,5-naphthyridine 1.1,2,3,4-tetrahydro-1,5-naphthyridine

合成工艺路线路线简述

    Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于氢气体系中,化学反应生成1,5-萘啶
    参考文献:Klisiecki; Sucharda,Roczniki Chemii,Vol. 7,P. 204
    标题:Klisiecki; Sucharda,Roczniki Chemii,Vol. 7,P. 204

    海关参考信息

    专利信息


    专利号:US-7160517-B2
    优先权日:2000-08-18
    标题 :Apparatus and methods for the automated synthesis of oligosaccharides
    发明人:SEEBERGER PETER H; PLANTE OBADIAH J
    权利人:MASSACHUSETTS INST OF TECHNOLG
    摘要:One aspect of the present invention relates to an apparatus for the efficient synthesis of oligosaccharides on a solid support, e.g., formed by subunit addition to terminal subunits immobilized on solid-phase particles. In certain embodiments, the apparatus of the present invention is used in combinatorial methods, e.g., as described herein, of synthesizing oligosaccharides.

    专利号:US-9353057-B2
    优先权日:2003-12-30
    标 题:Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
    发明人:GALLOP MARK A; DAI XUEDONG; SCHEUERMAN RANDALL A; RAILLARD STEPHEN P; MANTHATI SURESH K; YAO FENMEI; PHAN THU; LUDWIKOW MARIA; PENG GE; BHAT SEEMA
    权利人:XENOPORT INC
    摘要:Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.

    专利号:US-7230101-B1
    优先权日:2002-08-28
    标 题:Synthesis of methotrexate-containing heterodimeric molecules
    发明人:MURTHI KRISHNA K; SMITH CHASE C
    权利人:GPC BIOTECH INC
    摘要:The present invention relates to novel compositions of methotrexate-containing heterodimeric probe molecules, also known as chemical inducers of dimerization (CID), useful in three-hybrid assays. The invention further relates to synthesis of said compositions and their intermediates. Another aspect of the invention is a method for using the heterodimeric probe molecules described herein in drug screens to identify potential protein targets to a given ligand, optimize protein-ligand interactions, or identify potential ligands for a given protein target. In certain embodiments, the invention contemplates the synthesis of the following methotrexate-containing heterodimeric probe:

    专利号:US-10711138-B2
    优先权日:2016-04-08
    标题:Intermediates and procedures for the synthesis of functional materials
    发明人:KIRSCH PEER; GUNST SUSANN
    权利人:MERCK PATENT GMBH
    摘要:The present invention relates to heteroaromatic compounds which have two different reactive groups, their use in the synthesis of asymmetrically substituted compounds, and synthesis processes in which the compounds according to the invention are reacted sequentially with two different compounds, whereby an asymmetrically substituted compound is formed.

    专利号:US-8569560-B2
    优先权日:2006-10-13
    标题 :Synthesis of terminal alkenes from internal alkenes via olefin metathesis
    发明人:SCHRODI YANN; PEDERSON RICHARD L; KAIDO HIROKI; TUPY MICHAEL J
    权利人:ELEVANCE RENEWABLE SCIENCES
    摘要:This disclosure relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by an olefin metathesis catalyst. According to one aspect, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting, in the presence of a ruthenium alkylidene metathesis catalyst, an olefinic substrate comprised of at least one internal olefin with a cross metathesis partner comprised of an alpha olefinic reactant, under reaction conditions effective to allow cross-metathesis to occur, wherein the reaction conditions include a reaction temperature of at least 35° C. The methods, compositions, reactions and reaction systems herein disclosed have utility in the fields of catalysis, organic synthesis, and industrial chemistry.

    专利号:US-7692019-B2
    优先权日:2000-12-04
    标 题:Methods for the stereoselective synthesis of substituted piperidines
    发明人:AQUILA BRIAN M; BANNISTER THOMAS D; CUNY GREGORY D; HAUSKE JAMES R; HEFFERNAN MICHELE L R; HOEMANN MICHAEL Z; KESSLER DONALD W; SHAO LIMING; WU XINHE; XIE ROGER L
    权利人:SEPRACOR INC
    摘要:One aspect of the present invention relates to methods of synthesizing substituted piperidines. A second aspect of the present invention relates to stereoselective methods of synthesizing substituted piperidines. The methods of the present invention will find use in the synthesis of compounds useful for treatment of numerous ailments, conditions and diseases that afflict mammals, including but not limited to addiction and pain. An additional aspect of the present invention relates to the synthesis of combinatorial libraries of the substituted piperidines using the methods of the present invention. An additional aspect of the present invention relates to enantiomerically substituted pyrrolidines, piperidines, and azepines.
    斯芬克司药物研发(天津)股份有限公司
    ⚠️ 未注册 · 未认证企业
    ⚠️ 该商家尚未完成注册及企业认证,请用户仔细辨别,谨慎交易。
    数据来源于公开网络搜索,平台未作核实,请自行辨别。
    🏢敬请 企业认领
    🏬开设公司展台
    📢获取免费会员权益
    🎖️点亮专属注册企业标签
    📇展现公司完整信息 样本查看立即注册认领 →
    网址: http://www.sphinxpharm.com
    电话: 022-66211289-843 13672102692👤
    📞斯芬克司药物研发(天津)股份有限公司 ⚠️参考联系方式

    销售电话:022-66211289-843 13672102692
    邮箱:tangjie@sphinxscientificlab.com
    🆔 联系时候可告知是从"百琢研"平台获取的信息.
    ⚠️ 声明: 该企业未认证、未认领,请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实,百琢研不参与任何交易。企业认领注册入口→

    ⚠️ 未注册 · 未认证企业
    注册入口 备注: 📌 数据来源说明:本展台内容基于各搜索引擎等公开数据整理,仅作展示用途。请用户自行辨别 ✉️ 若企业需抹除展台内容或有异议, 请通过页面底部联系方式告知我们,我们会尽快处理。
    第 1 / 1 页
    现货

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1107/s1600536811006209
    摘要:Vennila KN, Prabha K, Prasad KJ, Velmurugan D. 7-(4-Meth-oxy-phen-yl)-4,9-dimethyl-N-(4-methyl-phen-yl)-5,12-diaza-tetra-phen-6-amine. Acta Crystallogr Sect E Struct Rep Online. 2011 Apr 01;67(Pt 4):o762–3.
    参考文献:10.1107/s1600536811012943
    摘要:Mudraboyina BP, Wang HB, Newbury R, Wisner JA. 2,6-Diamino-pyridinium tetra-phenyl-borate-1,2-bis-(5,7-dimethyl-1,8-naphthyridin-2-yl)diazene (1/1). Acta Crystallogr Sect E Struct Rep Online. 2011 May 01;67(Pt 5):o1222.
    参考文献:10.1107/s1600536811016485
    摘要:Oyama D, Yuzuriya K, Takase T. Aqua[2-(2-pyridyl)-1,8-naphthyridine-κ2N1,N2](2,2′:6′,2′′-terpyridine-κ3N,N′,N′′)ruthenium(II) bis(hexafluoridophosphate) acetone sesquisolvate. Acta Crystallogr E Struct Rep Online. 2011 May 11;67(6):m737–8. doi: 10.1107/s1600536811016485.
    参考文献:10.1007/s10895-011-0915-2
    摘要:Patil SR, Shelar DP, Rote RV, Jachak MN. A fluorescence study of new angular polycyclic blue light-emitting pyrazolo[3,4-h][1,6]naphthyridine and their interaction with bovine serum albumin (BSA). J Fluoresc. 2011 Nov;21(6):2037–52. doi: 10.1007/s10895-011-0915-2.
    📝 需求与反馈
    尽可能描述清楚需求与问题信息
    ×

    通知