专利号:US-4929752-A 优先权日:1986-09-23 标题:Process for the preparation of 1-amine-2-naphthol-4-sulfonic acid 发明人:ALBRECHT BERNHARD; BEYRICH JUERGEN 权利人:CIBA GEIGY CORP 摘要:There is disclosed an improved semi-continuous and continuous process for the preparation of 1-amino-2-naphthol-4-sulfonic acid by nitrosation of 2-naphthol, addition of bisulfite, acidification with mineral acid and reduction of the reaction product so obtained, which comprises charging the reactor with the nitrosating agent and simultaneously adding 2-naphthol and mineral acid simultaneously in separate streams in the semi-continuous process, or charging the reactor with the reaction mass and simultaneously adding 2-naphthol, mineral acid and the nitrosating agent in separate streams in the continuous process. The product can be further used, without isolation, for the synthesis of dyes.
专利号:US-7402439-B2 优先权日:2001-07-10 标题 :Method of operating an integrated structure of multilayer flow microchannel 发明人:KITAMORI TAKEHIKO; TOKESHI MANABU; HIBARA AKIHIDE 权利人:KANAGAWA KAGAKU GIJUTSU AKAD 摘要:An integrated structure of multilayer flow microchannel, which comprises a plurality of microchannels in which parallel multilayer flow that involves the interface of fluids is formed, arranged on various positions of a substrate, wherein each of the multilayer flow microchannels is communicated with another multilayer flow microchannel. A plurality of unit operations can be carried out continuously with high efficiency on a microchip, enabling high-degree microanalysis or precise chemical synthesis using the highly integrated structure of multilayer flow microchannel.
专利号:US-4604234-A 优先权日:1983-06-30 标题:Protein having cell growth stimulating action, composition thereof and method for producing the same 发明人:FUJII SETSURO; CHIKAZAWA NOBUMOTO; ARIMA TERUO; FUKUSHIMA MASAKAZU 权利人:SANWA KAGAKU KENKYUSHO CO 摘要:A protein effective in stimulating cell growth activity. The protein has a molecular weight of from 5,000 to about 160,000, is composed predominantly of neutral and acidic amino acids, contains a significant amount of glutamic acid and aspartic acid, and is substantially free of nucleoside phosphotransferase. The protein is useful as wound treatment agent and as promoting agent in the synthesis of DNA. A method of producing the protein and compositions containing the same are also disclosed.
专利号:CN-108395027-A 优先权日:2018-05-11 标 题:Production wastewater treatment process for the synthesis of 2-nitroso-1-naphthol-5-sulfonic acid intermediate from 1-naphthol-5-sulfonic acid
参考标题:New Nitrite Ionic Liquid (Il-Ono) And Nanoparticles Of Organosilane-Based Nitrite Ionic Liquid Immobilized On Silica As Nitrosonium Sources For Electrophilic Aromatic Nitrosation 作者:Hassan Valizadeh,Mohammad Amiri,Ashkan Shomali |发布日期:2011.12 摘要:Improved Method For The Synthesis Of Nitrosoarenes Has Been Developed Using A New Nitrite Ionic Liquid (Il-Ono) And Immobilized Nitrite Ionic Liquid. These Ionic Liquids Play As Nitrosonium Sources For Electrophilic Aromatic Nitrosation Of Active Aromatics At 0-5 °C. Their Action Was Accomplished In Water And The Satisfactory Results Were Obtained Under The Mild Conditions In Short Reaction Time.
合成参考文献
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