CAS: 119-81-3; 4-Methoxy-2-Nitroacetanilide

上下游产品

2-硝基-4-甲氧基苯胺 4-Methoxy-2-Nitroaniline 96-96-8

甲氧苯胺置于硫酸,硝酸,溶剂黄146体系中,化学反应生成4-甲氧基-2-硝基乙酰苯胺
参考文献:Diversified Synthesis Of Novel Quinoline And Dibenzo Thiazepine Derivatives Using Known Active Intermediates
标题:Diversified Synthesis Of Novel Quinoline And Dibenzo Thiazepine Derivatives Using Known Active Intermediates
摘要:新型药物的开发以控制常规药物治疗中抗药性感染是当今的需求.通过趋同合成法开发了少量与抗溃疡相关的衍生物.成功合成的衍生物包括二苯并噻嗪啶-吡啶(sln11-Sln15)和苯并咪唑-氢奎宁基衍生物(sln16-Sln20).在最终步骤中采用了微波,超声和常规技术进行耦合.有效的技术被识别为超声技术,主要体现在时间和产率上.报告的化合物通过元素分析和谱学研究(如1H,13C NMR和质谱)进行了结构表征.
Doi:10.14233/ajchem.2013.14818

专利信息

专利号:WO-2004092142-A1
优先权日:2003-04-17
标 题:An improved process for manufacture of substituted benzimidazoles
发明人：VYAS KETAN DHANSUKHAL; SINGH DHARMENDRA; NANDAVADEKAR SANJAY; BHISE SANJAY; JADHAV ATUL; DESAI HEMAL
权利人:IPCA LAB LTD; VYAS KETAN DHANSUKHAL; SINGH DHARMENDRA; NANDAVADEKAR SANJAY; BHISE SANJAY; JADHAV ATUL; DESAI HEMAL
摘要:The present invention relates to a process for the production of benzimidazole derivatives comprising providing an amino acetamido benzene derivative; and condensing and cyclising the aminoacetamido benzene derivative in the presence of a base and in the presence of a cyclising agent under conditions effective to form the benzimidazole derivative. The acetamido benzene derivative has the formula (I) wherein R is OMe or OCHF2. The resulting substituted benzimidazoles are key intermediates in the synthesis of H<+>/K<+>-ATPase irreversible inhibitors, most particularly Omeprazole.

专利号:RU-2030392-C1
优先权日:1991-04-01
标 题 :Method of synthesis of 3-nitro-4-aminoanisole

专利号:CN-113651713-B
优先权日:2021-08-19
标 题:Synthesis method of high-purity 2-nitro-4-acetylaminoanisole