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4-甲基苯甲酸叔丁酯 Tert-Butyl 4-Methylbenzoate 13756-42-8
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对甲基苯甲酸 P-Toluic Acid 99-94-54-甲基苯甲酸叔丁酯置于n-溴代丁二酰亚胺(Nbs)体系中,化学反应生成4-溴甲基苯甲酸叔丁酯
参考文献:用于基于fmoc的固相肽合成的4-羧基苯丙氨酸及其衍生物的立体定向合成
标题:用于基于fmoc的固相肽合成的4-羧基苯丙氨酸及其衍生物的立体定向合成
摘要:获得n α-苄氧羰基-L-酪氨酸(ø-三氟甲基)苄基酯,我们准备了使用钯(0)催化的羰基化反应对映体纯的4-Carboxyphenylalanine和4-Methoxycarbonylphenylalanine衍生物.这些非天然氨基酸被适当地保护,并用于使用fmoc /叔丁基方法的固相肽合成中.
Doi:10.1016/s0040-4039(96)01490-6
专利信息
专利号:US-11034664-B1
优先权日:2020-05-11
标题 :Synthesis of cyclic carbonate monomers
发明人:PARK NATHANIEL H; HEDRICK JAMES L; PIUNOVA VICTORIA A; ARRECHEA PEDRO; ERDMANN TIM
权利人:IBM
摘要:Techniques regarding the synthesis of cyclic carbonate monomers are provided. For example, one or more embodiments described herein can comprise a method, which can include cyclizing a functionalized diol monomer with N,N′-carbonyldiimidazole, wherein the cyclizing produces a cyclic carbonate monomer and an imidazole carbamate. The method can also include activating the imidazole carbamate with an acid, wherein the activating promotes cyclization of the imidazole carbamate into the cyclic carbonate monomer.
专利号:US-9156840-B2
优先权日:2010-06-18
标题:D2 antagonists, methods of synthesis and methods of use
发明人:LUEHR GARY W; SUNDARAM ARATHI; JAISHANKAR PRIYADARSHINI; PAYNE PHILIP W; DRUZGALA PASCAL
权利人:ALTOS THERAPEUTICS LLC
摘要:Provided are D 2 or D 3 antagonist compounds and pharmaceutical compositions of formula I n nand pharmaceutically acceptable salts thereof, or isomers thereof, wherein R 1 , R 2 and R 3 are as defined herein. The invention further comprises methods for making the compounds of the invention and methods for the treatment of conditions mediated by the dopamine D 2 or D 3 receptor from the compounds of the invention.
专利号:CZ-333895-A3
优先权日:1991-12-04
标 题:Starting compounds for synthesis of serine-prosthetic inhibitor
专利号:US-8691836-B2
优先权日:2010-06-18
标题 :D2 antagonists, methods of synthesis and methods of use
专利号:US-2014350005-A1
优先权日:2010-06-18
标题 :D2 antagonists, methods of synthesis and methods of use
专利号:WO-2011160084-A1
优先权日:2010-06-18
标题:D2 antagonists, methods of synthesis and methods of use