CAS: 101-99-5; Ethyl Phenylcarbamate

该化合物是一种碳酸酯化合物,其特点是配方C9H11NO2.它是有机合成,特别是生产药品,农用化学品和特殊化学品的多用途中间体.该化合物在标准条件下具有稳定性,并显示出适合核生殖替代和凝聚反应的再活动性.其苯基和乙基功能组有助于其改变分子框架的效用.乙基N-苯基碳酸酯因其与一系列溶剂的一贯纯度和兼容性而受到重视,便于其在实验室和工业应用中的使用.建议适当的处理和储存以保持其完整性.

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3422-01-3 103-70-8 7451-53-8

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合成工艺路线路线简述

    📜苯甲酰硝基甲烷置于ammonium Cerium (Iv) Nitrate,2,2,6,6-四甲基哌啶氧化物,氧气体系中,用 乙酸乙酯 用作溶剂,60.0~80.0 °C,101.33 Kpa 条件下,反应 36.0H,反应生成N-二苯尿烷
    参考文献:硝酸铈铵(can)通过保留氧代基团的两个cc键断裂催化酮的改性
    标题:硝酸铈铵(can)通过保留氧代基团的两个cc键断裂催化酮的改性
    摘要:已经公开了一种简单的硝酸铈铵(can)通过双c-C键裂解策略催化酮的官能化的方法.该反应为氨基甲酰叠氮化物提供了温和,实用的方法,氨基甲酰叠氮化物是有机合成中的通用中间体和结构单元.基于相关的机理研究,提出了一个独特且可行的c-c键和n-o键裂解过程,其中氧化胺化中间体在该反应中起着重要的作用.
    Doi:10.1021/ol5014476

    专利信息


    专利号:US-11548898-B2
    优先权日:2017-07-06
    标题 :Synthesis of halichondrins
    发明人:KISHI YOSHITO; AI YANRAN; YE NING; WANG QIAOYI; YAHATA KENZO; ISO Kentaro; NAINI SANTHOSH REDDY; YAMASHITA SHUJI; LEE JIHOON; OHASHI ISAO; FUKUYAMA TAKASHI
    权利人:HARVARD COLLEGE; EISAI R&D MAN CO LTD
    摘要:The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

    专利号:US-4749806-A
    优先权日:1984-12-28
    标题:Process for the synthesis of isocyanates and of isocyanate derivatives
    发明人:TKATCHENKO IGOR; JAOUHARI RABIH; BONNET MICHEL; DAWKINS GORDON; LECOLIER SERGE
    权利人:POUDRES & EXPLOSIFS STE NALE
    摘要:The present invention relates to a process for the synthesis of isocyanates and of isocyanate derivatives. Isocyanates are obtained by reacting an organic halide with a metal cyanate in an organic medium in the presence of a catalyst consisting of a complex of nickel with at least one organic ligand, in which complex the nickel is in the zero oxidation state. A carbamate or a urea, respectively, are obtained by a subsequent reaction with a hydroxy compound or a primary or secondary amine. Isocyanates and their derivatives are used especially either as refined synthesis agents for the production of pesticides and medications, or as monomers or comonomers for the preparation of many macromolecular compounds.

    专利号:US-7022871-B2
    优先权日:1999-12-27
    标 题 :Process for the synthesis of polycarbamates
    发明人:CHAUDHARI RAGHUNATH VITTHAL; KELKAR ASHUTOSH ANANT; GUPTE SUNIL PURUSHOTTAM; DIVEKAR SUNIL SADASHIV; GANAPATHY SUBRAMANIAN
    权利人:HUNTSMAN INT LLC
    摘要:Process for the synthesis of polyurethane derivatives from aromatic polyamine compounds. The method involves the reaction of an aromatic polyamine compound with CO and O 2 in the presence of a catalyst comprising a Group VIII or lanthanide metal on a solid support and a halogenide promoter.

    专利号:EP-1242368-B1
    优先权日:1999-12-27
    标 题 :Process for the synthesis of polycarbamates
    发明人:CHAUDHARI RAGHUNATH VITTHAL; KELKAR ASHUTOSH ANANT; GUPTE SUNIL PURUSHOTTAM; DIVEKAR SUNIL SADASHIV; GANAPATHY SUBRAMANIAN
    权利人:HUNTSMAN INT LLC
    摘要:Process for the synthesis of polyurethane derivatives from aromatic polyamine compounds. The method involves reaction of an aromatic polyamine compound with CO and O2 in the presence of a catalyst comprising a Group VIII or lanthanide metal on a solid support and a halogenide promoter.

    专利号:US-5171676-A
    优先权日:1991-10-31
    标 题 :Method of introducing hydroxyl groups into artemisinin and its derivatives
    发明人:ZIFFER HERMAN; HU YULIN
    权利人:US HEALTH
    摘要:The fungus Beauveria sulfurescens has been employed to introduce hydroxyl groups into artemisinin and derivatives of artemisinin, an antimalarial. Hydroxylated derivatives of artemisinin and derivatives of artemisinin produced thereby possess antimalarial activity, and can serve as intermediates in the synthesis of further derivatives useful in treating malaria.

    专利号:US-8106031-B2
    优先权日:2006-05-02
    标题:Hydrolytically-resistant boron-containing therapeutics and methods of use
    发明人:LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A
    权利人:LEE VING; PLATTNER JACOB J; BENKOVIC STEPHEN J; BAKER STEPHEN J; MAPLES KIRK R; BELLINGER-KAWAHARA CAROLYN; AKAMA TSUTOMU; ZHANG YONG-KANG; SINGH RAJESHWAR; SAURO VITTORIO A; ANACOR PHARMACEUTICALS INC
    摘要:Compositions and methods of use of boron derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by fungi, yeast, bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Thullen, S. M.; Ashley, M. A.; Rovis, T., Science of Synthesis: Photocatalysis in Organic Synthesis, (2018) 1, 240.
    摘要:Clark, K. F.; Dimitrova, D.; Murphy, J. A., Science of Synthesis, (2020) , 2.
    摘要:Galczynski, J.; Huang, H.; Lambert, T. H., Science of Synthesis: Special Topics, (2021) 1, 330.
    摘要:Oakwood Products, Inc; Fine Organics Manufacturing Facility. Available at
    摘要:Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 14th Edition. John Wiley & Sons, Inc. New York, NY 2001., p. 476
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