CAS: 91-19-0; Quinoxaline

相似化合物

6344-72-5 7251-61-8 50998-18-0

上下游产品

CAS号95-54-5 邻苯二胺(OPD) | CAS号1074-12-0 苯基丙醇水合物 | CAS号107-21-1 乙二醇 | CAS号3476-89-9 1,2,3,4-四氢喹喔啉 | CAS号2423-66-7 喹喔啉1,4-二氧化物 | CAS号57-55-6 丙二醇 | CAS号60418-63-5 1-(2-azidopheny... | CAS号36856-92-5 Quinoxaline, 2-... | CAS号273-09-6 依托唑灵 | CAS号105702-07-6 2-(2-methylphen... | CAS号4744-50-7 2,3-吡嗪二酸酐 | CAS号3476-89-9 1,2,3,4-四氢喹喔啉 | CAS号5021-45-4 2-(4-溴苯基)喹喔啉 | CAS号18503-48-5 2-tert-butylqui... | CAS号25871-20-9 2-pivaloylquino... | CAS号18522-05-9 2-t-butyl-1,2,3... | CAS号108163-91-3 2-t-butyl-1,2-d... | CAS号231-23-2 吡嗪-喹啉 | CAS号20595-03-3 1-methylquinoxaline

1,2-二硝基苯置于氢气体系中,用 二乙二醇二甲醚 作为反应溶剂,80.0~140.0 °C,1.0 Mpa 条件下,反应 48.0H,反应生成 喹喔啉
参考文献:将生物质转化为化学物质:使用负载型金纳米颗粒作为催化剂,从生物质衍生的乙二醇和1,2-二硝基苯衍生物一锅法分两步和三步合成喹喔啉
标题:将生物质转化为化学物质:使用负载型金纳米颗粒作为催化剂,从生物质衍生的乙二醇和1,2-二硝基苯衍生物一锅法分两步和三步合成喹喔啉
摘要:通过使用负载在纳米二氧化铈(au / Ceo 2)或水滑石上的金纳米粒子,开发了一种有效的,选择性的一锅两步方法,该方法通过邻二醇与1,2-苯二胺衍生物的氧化偶联来合成喹喔啉.(au / Ht)作为催化剂,空气作为氧化剂,没有任何均相碱.反应动力学表明,反应控制步骤是将二醇氧化为α-羟基羰基化合物.此外,已经成功地进行了以1,2-二硝基苯和1,2-丙二醇为原料的2-甲基喹喔啉的一锅式三步合成,最终产物的转化率为98%,总产率为83%.
DOI:10.1016/j.Jcat.2012.05.002

专利信息

专利号:WO-2023233371-A1
优先权日:2022-06-03
标 题:A continuous flow process for synthesis of organic azides
发明人：GNANAPRAKASAM BOOPATHY; PANDEY AKANKSHA M; MONDAL SHANKHAJIT
权利人:INDIAN INSTITUTE OF SCIENCE EDUCATION AND RES PUNE IISER PUNE
摘要:The present disclosure relates generally to the field of synthetic organic chemistry. More specifically, the disclosure is directed to a continuous flow process for synthesis of azides from alcohols and peroxides, wherein the process comprises azidation with trimethylsilyl azide and a catalyst Amberlyst-15. It is a non-hazardous, mild and controlled reaction giving good yields of azides. The azides can be further employed for synthesis of medicinally and industrially useful chemicals.

专利号:US-7160517-B2
优先权日:2000-08-18
标题 :Apparatus and methods for the automated synthesis of oligosaccharides
发明人：SEEBERGER PETER H; PLANTE OBADIAH J
权利人:MASSACHUSETTS INST OF TECHNOLG
摘要:One aspect of the present invention relates to an apparatus for the efficient synthesis of oligosaccharides on a solid support, e.g., formed by subunit addition to terminal subunits immobilized on solid-phase particles. In certain embodiments, the apparatus of the present invention is used in combinatorial methods, e.g., as described herein, of synthesizing oligosaccharides.

专利号:US-7956011-B2
优先权日:2005-05-04
标题:Materials and methods for the photodirected synthesis of oligonucleotide arrays
发明人：SERAFINOWSKI PAWEL JERZY; GARLAND PETER BRYAN
权利人:CANCER RES INST ROYAL
摘要:Materials and methods for photodirected synthesis of oligonucleotide arrays on a solid substrate by photodirected synthesis are disclosed which employ a film formed from (i) a photoacid generator that on photolysis generates acid that is capable of directly removing the protecting group of the linker molecules or oligonucleotides and (ii) a polymer substantially lacking electronegative heteroatoms that are capable of hydrogen bonding with photogenerated acid. Methods of synthesizing an oligomer arrays are also described that use a film that restricts diffusion of reactants and products on the substrate during synthesis of the array and which includes a precursor of a deprotecting reagent. The method involves removing one or more of the non-required products of the deprotection reaction from the reactive array elements at which they are produced during the reaction, in order to displace the deprotection reaction towards completion.

专利号:US-6376676-B1
优先权日:1993-06-30
标题 :Intermediates in the synthesis of (±)-camptothecin and related compounds and synthesis thereof
发明人：CURRAN DENNIS P; LIU HUI
权利人:UNIV PITTSBURGH
摘要:The present invention provides a short, convergent total synthesis of novel intermediates in the synthesis of (±)-camptothecin and related compounds. The present synthesis scheme includes a novel 4+1 radical annulation followed by another cyclization to simultaneously assemble rings B and C of the camptothecin compound. The present invention also provides novel chemical intermediates for such 4+1 radical annulations.

专利号:US-7230101-B1
优先权日:2002-08-28
标 题:Synthesis of methotrexate-containing heterodimeric molecules
发明人：MURTHI KRISHNA K; SMITH CHASE C
权利人:GPC BIOTECH INC
摘要:The present invention relates to novel compositions of methotrexate-containing heterodimeric probe molecules, also known as chemical inducers of dimerization (CID), useful in three-hybrid assays. The invention further relates to synthesis of said compositions and their intermediates. Another aspect of the invention is a method for using the heterodimeric probe molecules described herein in drug screens to identify potential protein targets to a given ligand, optimize protein-ligand interactions, or identify potential ligands for a given protein target. In certain embodiments, the invention contemplates the synthesis of the following methotrexate-containing heterodimeric probe:

专利号:US-2008086013-A1
优先权日:2006-06-15
标 题:Carbometallation of alkynes and improved synthesis of uniquinones
发明人：LIPSHUTZ BRUCE H
权利人:UNIV CALIFORNIA
摘要:Methods for the carbometallation of alkynes are presented. Those are useful for the synthesis of CoQ 10 and other ubiquinones as well as for the synthesis of ubiquinol analogs.