CAS: 437-50-3; 1,7-Dihydroxy-3-Methoxy-9H-Xanthen-9-One
该化合物是主要在各种植物中发现的自然产生的氟氯素化合物,其特点是黄色晶状外观,以潜在的抗氧化特性著称,Gentisin展示了一系列生物活动,包括抗炎和抗微生物效应,使其对药理研究感兴趣.该化合物的结构复杂,包括多种氢氧基化合物,有助于其再活动以及与生物系统的互动.Gentisin在有机溶剂中溶解,但水溶性有限,可能影响其生物利用率和药剂中的应用.此外,研究表明,Gentisin可能在改变各种生物化学途径方面发挥作用,尽管还需要进一步研究,以充分阐明其行动和治疗潜力的机制.
- 英文名称1,7-Dihydroxy-3-Methoxy-9H-Xanthen-9-One
- 中文名称龙胆根素
- IUPAC名称Gentisin
- 其它别名Gentisin; Gentiin; 3-Methoxyeuxanthone; 1,7-Dihydroxy-3-Methoxy-9H-Xanthen-9-One; Gentisin(P)(Please Call); 1,7-Dihydroxy-3-Methoxy-9H-Xanthen-9-On; 1,7-Dihydroxy-3-Methoxy-Xanthen-9-On; 1,7-Dihydroxy-3-Methoxyxanthen-9-One
- CAS编号437-50-3
- MFCD编号:MFCD00075947
- EINECS号:207-114-1
- FDA UNII编号:K57MOP2HM0
- 分子式:C14H10O5分子量:258.23
- 产品CID: 1447080
- 产品分类生物化工 → 提取物 → 植物提取物
物理性质
MSDS等安全信息
上下游产品
1,3,7-三羟基-9H-氧杂蒽-9-酮 Gentitein 529-49-7合成工艺路线路线简述
- 合成目标产物 Gentisin 主要起始原料 2,5-Dihydroxybenzoic Acid
- (文献来源)合成步骤主要原料 2,5-Dihydroxybenzoic Acid
📜1-Hydroxy-3-Methoxy-7-[(2S,3R,4R,5R,6R)-3,4,5-Trihydroxy-6-[[(2S,3R,4S,5R)-3,4,5-Trihydroxyoxan-2-Yl]Oxymethyl]Oxan-2-Yl]Oxyxanthen-9-One 反应生成 龙胆根素
参考文献:Hayashi,Takaaki;Yamagishi,Takashi,Phytochemistry,27,(1988) N 11,C. 3696-3699
标题:Hayashi,Takaaki;Yamagishi,Takashi,Phytochemistry,27,(1988) N 11,C. 3696-3699
海关参考信息
- 2905110000-甲醇
2907221000-对苯二酚
2908199090-其他酚的卤化衍生物
2908999090-其他酚的硝化衍生物 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
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优先权日:2011-04-28
标 题:Automated equipment for the synthesis of peptide-based radiopharmaceuticals for diagnostic and/or therapeutic use
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优先权日:2011-09-09
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优先权日:2021-07-14
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供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Yin C, Xie L, Guo Y. Phytochemical analysis and antibacterial activity of Gentiana macrophylla extract against bacteria isolated from burn wound infections. Microb Pathog. 2018 Jan;114:25-28. doi: 10.1016/j.micpath.2017.10.049. Epub 2017 Oct 27. doi: 10.1248/cpb.c15-00776. doi: 10.3390/molecules201119703. doi: 10.1371/journal.pone.0061393. Print 2013.
5: Wani BA, Ramamoorthy D, Rather MA, Arumugam N, Qazi AK, Majeed R, Hamid A, Ganie SA, Ganai BA, Anand R, Gupta AP. Induction of apoptosis in human pancreatic MiaPaCa-2 cells through the loss of mitochondrial membrane potential (ΔΨm) by Gentiana kurroo root extract and LC-ESI-MS analysis of its principal constituents. Phytomedicine. 2013 Jun 15;20(8-9):723-33. doi: 10.1016/j.phymed.2013.01.011. Epub 2013 Mar 1. Epub 2007 Jul 10. Undetermined Language.
合成参考文献
参考文献:10.1007/bf01484937
摘要:SIEGRIST H, MEYER HH. [Potassium content of cerebrospinal fluid]. Klin Wochenschr. 1954 Jun 15;32(23-24):549–52. doi: 10.1007/bf01484937.
参考文献:10.1007/bf01484938
摘要:PFENNIGSDORF G, PONSOLD W. [Comparative studies on urinary excretion products following administration of salicylamide, sodium salicylate or salicylic acid in cat and in rabbit]. Klin Wochenschr. 1954 Jun 15;32(23-24):552–6. doi: 10.1007/bf01484938.
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