CAS: 40107-93-5; 6,7-Dihydro-5H-Pyrrolo[3,4-B]Pyridin-5-One

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CAS号89-00-9 吡啶-2,3-二羧酸 | CAS号4664-00-0 2,3-吡啶二甲酰亚胺

📜2,3-吡啶二酰亚胺置于sodium Tetrahydroborate,溶剂黄146,锌体系中,用 甲醇,氯仿 作为反应溶剂,化学反应 6.0H,反应生成 6,7-二氢吡咯[3,4-B]并吡啶-5-酮
参考文献:新型的人工氢化物辅助氟化辅因子的氧化还原生物催化荧光传感评估新方法
标题:新型的人工氢化物辅助氟化辅因子的氧化还原生物催化荧光传感评估新方法
摘要:开发了新的人工氟辅因子以替代天然辅因子nad(p),具有较高的氢化物转移能力.更重要的是,我们为评估建立了一种新的快速筛选方法.
DOI:10.1039/c6Cc02002J

专利信息

专利号:US-9586964-B2
优先权日:2011-10-28
标 题:Substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M1
发明人：LINDSLEY CRAIG W; CONN P JEFFREY; WOOD MICHAEL R; HOPKINS COREY R; MELANCON BRUCE J; POSLUSNEY MICHAEL S; ENGERS DARREN W
权利人:UNIV VANDERBILT
摘要:In one aspect, the invention relates to substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one analogs compounds, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the muscarinic acetylcholine receptor M 1 (mAChR M 1 ); synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating neurological and psychiatric disorders associated with muscarinic acetylcholine receptor dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

专利号:US-8536164-B2
优先权日:2010-12-20
标 题:Fused pyridine compounds as casein kinase inhibitors
发明人：BUTLER TODD W; CHANDRASEKARAN RAMALAKSHMI Y; MENTE SCOT R; SUBRAMANYAM CHAKRAPANI; WAGER TRAVIS T
权利人:BUTLER TODD W; CHANDRASEKARAN RAMALAKSHMI Y; MENTE SCOT R; SUBRAMANYAM CHAKRAPANI; WAGER TRAVIS T; PFIZER
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula I: n nand pharmaceutically acceptable salts thereof, wherein X, Y, A, R 4 , n, and R 7 are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.