CAS: 387827-19-2; Tert-Butyl 4-(3-Aminophenyl)Piperidine-1-Carboxylate
该化合物是一种化学化合物,其特征为管状核心结构,由六人组成,内含一个氮原子的环形六人,该化合物的特征为叔丁基酯组,有助于其亲脂性和有机溶剂中的潜在溶解性;3-氨基苯分质的存在具有芳香性质,可能影响其再活动及其与生物目标的相互作用;氨基化合物组还可能参与氢的结合,增强其作为药用化学药剂药用药剂的潜力;该化合物因其结构特征可能赋予特定生物活动,在各个领域,包括药物开发和有机合成方面都有意义;其稳定性,反应性及潜在应用可能受诸如pH,温度和其他功能组在反应环境中的存在等因素的影响;与许多有机化合物一样,在与该物质打交道时,应观察适当的处理和安全措施.
- 英文名称Tert-Butyl 4-(3-Aminophenyl)Piperidine-1-Carboxylate
- 中文名称4-(3-氨基苯基)哌啶-1-羧酸叔丁酯
- IUPAC名称tert-butyl 4-(3-aminophenyl)piperidine-1-carboxylate
- 其它别名3-(1-Boc-4-哌啶基)苯胺; 4-(3-Amino-Phenyl)-Piperidine-1-Carboxylic Acid Tert-Butyl Ester
- CAS编号387827-19-2
- MFCD编号:MFCD03701248
- EINECS号:982-975-0
- 分子式:C16H24N2O2分子量:276.37
- 产品CID: 1399952
- 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物
物理性质
MSDS等安全信息
欧盟法规
C&L通报上下游产品
tert-butyl 1,2,3,6-tetrahydro-4-(3-nitrophenyl)pyridine-1-carboxylate tert-butyl 4-[3-(amino)phenyl]-1,2,3,6-tetrahydro-1-pyridinecarboxylate isopropylamine N-tert-butyloxycarbonylpiperidin-4-one 4-[3-[1,3-bis(tert-butoxycarbonyl)hexahydropyrimidin-2-ylidene]aminophenyl]piperidine-1-carboxylic acid tert-butyl ester 4-(3-propionamidophenyl)piperidine-1-carboxylic acid tert-butyl ester 4-(3-aminophenyl)piperidine tert-butyl 4-(3-{[(2-phenoxy-3-pyridinyl)carbonyl]amino}phenyl)-1-piperidinecarboxylate合成工艺路线路线简述
📜间溴硝基苯置于tris-(Dibenzylideneacetone)Dipalladium(0),Palladium 10% On Activated Carbon,氢气,Sodium Carbonate,Tri Tert-Butylphosphoniumtetrafluoroborate体系中,用 1,4-二氧六环,乙醇,水 作为反应溶剂,20.0~90.0 °C,275.8 Kpa 条件下,反应 30.33H,反应生成 4-(3-氨基苯基)-哌啶-1-羧酸叔丁酯
参考文献: Braf Degraders[fr] Agents De Dégradation De Braf
标题: Braf Degraders[fr] Agents De Dégradation De Braf
摘要:本发明提供了能够特异性降解braf的化合物.这些化合物可用于治疗各种癌症.
海关参考信息
- 2902600000-乙苯
2902700000-异丙基苯
2905122000-异丙醇
2905143000-叔丁醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-2004058727-A1
优先权日:2002-12-20
标题 :Substituted 3,5-dihydro-4h-imidazol-4-ones for the treatment of obesity
发明人：CHEN YUANWEI; O'CONNOR STEPHEN JAMES; GUNN DAVID; NEWCOM JASON; CHEN JIANQING; YI LIN; ZHANG HAI-JUN; HUNYADI LASZLO MATYAS; NATERO REINA
权利人:BAYER PHARMACEUTICALS CORP; CHEN YUANWEI; O'CONNOR STEPHEN JAMES; GUNN DAVID; NEWCOM JASON; CHEN JIANQING; YI LIN; ZHANG HAI-JUN; HUNYADI LASZLO MATYAS; NATERO REINA
摘要:This invention relates to substituted 3,5-dihydro-4H-imidazol-4-ones compounds which are useful in the treatment of obesity and obesity-related disorders, and as weight-loss and weight-control agents. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.
