CAS: 27563-67-3; N-Methyldodecanamide

该化合物是一种脂肪酸氨化衍生物,其特征是12碳烷基链和甲基替代氨化物组,该化合物在有机溶剂中表现出显著溶性,在标准条件下表现出稳定性,适合表面活性制剂,润滑剂添加剂和特殊化学合成方面的应用.其两栖性质允许进行有效的间歇活动,而甲基组则加强了与疏水系统的兼容性.N-甲基乙二氧安非他胺也用于研究,作为研究基于氨的相互作用和自组过程的示范化合物.产品通常供应纯度高,确保工业和实验室环境的一贯性能.

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629-54-9 638-58-4 3061-75-4

上下游产品

methyl n-dodecanoateN-methyldodecylamine N-acyl sarcosinate methyl n-dodecanoate ethyl laurate

合成工艺路线路线简述

    月桂酸置于氯化亚砜体系中,用 乙醚 用作溶剂,化学反应生成N-甲基十二胺
    参考文献:Dodecanoic Acid Derivatives: Synthesis,Antimicrobial Evaluation And Development Of One-Target And Multi-Target Qsar Models
    标题:Dodecanoic Acid Derivatives: Synthesis,Antimicrobial Evaluation And Development Of One-Target And Multi-Target Qsar Models
    摘要:In This Study A Series Of Dodecanoic Acid Derivatives (1-30) Were Synthesized And Evaluated For In Vitro Antimicrobial Activity Against The Panel Of Gram Positive,Gram Negative Bacterial And Fungal Strains. 4-Nitro Phenyl Dodecanoate (4) And Quinolin-8-Yl Dodecanoate (5) Emerged As Most Effective Antibacterial Agents,And 1-(4-Benzylpiperazin-1-yl) Dodecan-1-One (15) Was Found To Be The Most Effective Antifungal Agent Amongst The Synthesized Dodecanoic Acid Derivatives. Quantitative Structure Activity Relationship (Qsar) Studies Performed By The Development Of One-Target And Multi-Target Models Indicated That Multi-Target Model Was Effective In Describing The Antimicrobial Activity Of Dodecanoic Acid Derivatives As Well Demonstrated The Importance Of Topological Parameter,Zero-Order Molecular Connectivity Index ((0)Chi).
    Doi:10.1007/s00044-010-9383-5

    海关参考信息

    专利信息


    专利号:US-4379928-A
    优先权日:1981-03-04
    标 题 :Synthesis of amides
    发明人:THEODOROPULOS SPYROS
    权利人:UNION CARBIDE CORP
    摘要:Alkyl amides have been synthesized from cyclic anhydrides, carboxyl acids and their esters by contacting them with an amine carbamic acid salt.

    专利号:EP-0062161-B1
    优先权日:1981-03-04
    标 题:Synthesis of amides using carbamic-acid salts

    专利号:EP-0062161-A1
    优先权日:1981-03-04
    标 题 :Synthesis of amides using carbamic-acid salts

    专利号:CA-1175858-A
    优先权日:1981-03-04
    标 题 :Synthesis of amides

    专利号:US-2025026716-A1
    优先权日:2021-11-25
    标 题:Synthesis process of fatty acyl taurine salt

    专利号:CN-114181118-A
    优先权日:2021-11-25
    标题:A kind of synthesis technique of fatty acyl taurine
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    合成参考文献


    参考文献:10.1007/bf02678720
    摘要:Micich TJ. A Rapid Synthesis of Fatty Acyl Urea Derivatives. J Americ Oil Chem Soc. 1982 Feb;59(2):92–4. doi: 10.1007/bf02678720.
    参考文献:10.1007/s11270-023-06580-6
    摘要:Ding Q, Zhu H. Metagenomic Analysis of Microbial Communities in Indoor Water Cultures: a Case Study in an Educational Building. Water Air Soil Pollut. 2023 Aug;234(8). doi: 10.1007/s11270-023-06580-6.
    参考文献:10.1007/s11705-025-2531-8
    摘要:Ji W, Zhang L, Duan F. Nitrogen-enriched pyrolysis and catalytic pyrolysis of municipal sludge extract. Front. Chem. Sci. Eng. 2025 Mar 03;19(4). doi: 10.1007/s11705-025-2531-8.
    参考文献:10.1007/s11244-025-02160-6
    摘要:Kattelus J, Velasco JA, Auvinen P, Arandia A, Verkama E, Meinander K, Jiang H, Karinen R, Puurunen RL. Hydrodeoxygenation and Hydrodenitrogenation of n-Hexadecanamide with Supported NiMo Sulfide Catalysts. Top Catal. 2025 Aug 25;68(20):2507–20. doi: 10.1007/s11244-025-02160-6.
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