CAS: 2586-62-1; 1-Bromo-2-Methylnaphthalene

该化合物是一种卤化芳烃化合物,配有分子式C11H9Br.它是一个有机合成的多用途中间体,特别是在制药,农用化学品和特殊化学品的制作方面.溴替代物可增强回活性,促进诸如铃木或Heck相交等交叉反应,而甲基组则提供额外的功能化机会.其稳定的氯化萘脊椎能确保多种反应条件下的稳健性.该化合物通常以高纯度固态供应,确保合成应用的一贯性.由于其定义明确的结构和再活性,1-Bromo-2-甲基甲烷是建立研究和工业环境中的复杂有机框架的宝贵基石.

结构式图片

相似化合物

20027-95-6 54357-18-5 3378-82-3

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上下游产品

CAS号91-57-6 2-甲基萘 | CAS号2246-44-8 1-氨基-2-甲基萘 | CAS号56-23-5 四氯化碳 | CAS号7726-95-6 溴素 | CAS号7553-56-2 碘 | CAS号75-15-0 二硫化碳 | CAS号109433-16-1 1-bromo-2-but-3... | CAS号35699-44-6 2-甲基-1-萘醛 | CAS号37763-43-2 1-溴-2-(溴甲基)萘 | CAS号3378-82-3 1-溴-2-萘甲醛 | CAS号14673-10-0 1-Naphthaleneme... | CAS号143901-96-6 1-fluoronaphtha... | CAS号15000-91-6 2-Naphthaleneme... | CAS号14304-75-7 1-氯萘-2-甲醛 | CAS号22865-55-0 1-chloro-4-(4-m... | CAS号91-57-6 2-甲基萘

合成工艺路线路线简述

    📜2-甲基萘置于溴,Potassium Acetate,溶剂黄146体系中,用 二氯甲烷 用作溶剂,化学反应 0.25H,以92%的收率获得1-溴-2-甲基萘
    参考文献:新型萘并[ A ]咔唑和苯并[ C ]咔唑的简明合成
    标题:新型萘并[ A ]咔唑和苯并[ C ]咔唑的简明合成
    摘要:从简单的吲哚前体开始,描述了萘并[ A ]咔唑和苯并[ C ]咔唑的合成.关键步骤包括使用suzuki-Miyaura反应提供2-或3-芳基取代的吲哚,以及叔丁醇钾和光辅助的芳香环形成反应.
    Doi:10.1016/j.Tet.2006.01.012

    海关参考信息

    专利信息


    专利号:US-11548838-B2
    优先权日:2021-02-02
    标 题:Process for synthesis of polyhydrocarbons as heat transfer agents
    发明人:MANDAL TANMAY; VANKUDOTH KRISHNA; SARASWAT MANISHA; ARORA AJAY KUMAR; KAGDIYAL VIVEKANAND; SAXENA DEEPAK; RAMAKUMAR Sankara Sri Venkata
    权利人:INDIAN OIL CORP LTD
    摘要:The present invention provides a one-pot process of synthesis of phenyl naphthalene compounds that are employed as heat transfer agents. More particularly, the present invention provides a process of preparation of 1-phenylnaphthalene and 2-methyl-1-phenylnaphthalene using refinery spent catalyst. These molecules are known for application as synthetic heat transfer fluids that deliver outstanding performance and thermal stability at continuously high operating temperatures. The reaction is carried out in aqueous medium using a spent catalyst which is a palladium based charcoal catalyst as obtained from various refinery processes. Further, the present invention provides a heat resistant formulation using the synthesized polyhydrocarbons, wherein the formulation is optimized with a free radical scavenger.

    专利号:US-5670698-A
    优先权日:1996-08-19
    标 题:Synthesis of 1-acetoxy-2-methylnaphthalene
    发明人:LIM MU-ILL; PAN YUH-GUO; STASAITIS LINAS; ANDERSON JAMES
    权利人:BRISTOL MYERS SQUIBB CO
    摘要:A one pot process is provided in which a Mannich base of the formula 5 is reacted with acetic anhydride to produce a diacetate derivative. Without any intermediate isolation, the derivative is hydrogenated to produce a reaction mixture containing 1-acetoxy-2-methylnaphthalene which is readily precipitated from the reaction mixture by addition of water. ##STR1##

    专利号:US-10196413-B2
    优先权日:2016-12-06
    标 题 :Chiral dihydrobenzoazaphosphole ligands and synthesis thereof
    发明人:BISWAS SOUMIK; DESROSIERS JEAN-NICOLAS; LAO KENDRICKS; MANGUNURU HARI P R; QU BO; RODRIGUEZ SONIA; SENANAYAKE CHRIS HUGH; SIEBER JOSHUA DANIEL; WANG XIAO-JUN; YEE NATHAN K; ZHANG YONGDA
    权利人:BOEHRINGER INGELHEIM INT
    摘要:This invention relates to novel phosphorous ligands useful for organic transformations. Methods of making and using the ligands in organic synthesis are described. The invention also relates to processes for preparing the novel ligands.

    专利号:US-6534627-B1
    优先权日:1989-10-23
    标题:Synthesis and use of amino acid fluorides as peptide coupling reagents
    发明人:CARPINO LOUIS A; EL-FAHAM AYMAN AHMED
    权利人:RES CORP TECHNOLOGIES INC
    摘要:The present invention is directed to the process of preparing a peptide comprising reacting a first amino acid or peptide with an amino acid fluoride of the formula: n or the acid fluoride salts thereof wherein n BLK is an N-amino protecting group; n AA is an amino acid residue; and n X is absent or a protecting group. n The amino acid fluoride is useful as a coupling agent in peptide synthesis.

    专利号:US-5360928-A
    优先权日:1989-10-23
    标题 :Synthesis and use of amino acid fluorides as peptide coupling reagents
    发明人:CARPINO LOUIS A; SADAT-AALAEE DEAN
    权利人:RES CORP TECHNOLOGIES INC
    摘要:A compound of the formula ##STR1## or the acid fluoride salts thereof wherein BLK is an N-amino protecting group or hydrogen n AA is an amino acid residue and n X is H or a protecting group useful as a coupling agent in peptide synthesis.

    专利号:US-2022242804-A1
    优先权日:2021-02-02
    标 题:Process for Synthesis of Polyhydrocarbons as Heat Transfer Agents

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: N A Vinokurova, Et Al. [参考文献]: Vopr Onkol. 1975;21(3):19-24.

    合成参考文献


    摘要:Black, D. A.; Fagnou, K., Science of Synthesis, (2010) 45, 572.
    摘要:Wolf, C., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 1, 880.
    摘要:Wolf, C., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 1, 863.
    摘要:Chetcuti, M. J., Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis, (2016) 1, 109.
    摘要:Chetcuti, M. J., Science of Synthesis: N-Heterocyclic Carbenes in Catalytic Organic Synthesis, (2016) 1, 82.
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