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erythromycin 9-deoxo-9-iminoerythromycin A erythromycin A erythromycin A enol ether 海关参考信息
- 2905122000-异丙醇
2905143000-叔丁醇
2905310000-1,2-乙二醇
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专利信息
专利号:RU-2045533-C1
优先权日:1990-07-18
标 题 :O-methyl derivatives of azithromycin a showing antibacterial activity, azithromycins as intermediate compounds for synthesis of o-methyl derivatives of azithromycin a and a method of synthesis of o-methyl derivatives of azithromycin a
专利号:US-2006074032-A1
优先权日:2000-11-29
标题 :Synthesis and separation of optically active isomers of erythromycin and their biological actions
发明人:SOMBERG JOHN; RANADE VASANT
权利人:ACADEMIC PHARM INC
摘要:The present invention provides methods for purifying and using optically active isomers of erythromycin as well as compositions comprising such optically active isomers. Such optically active isomers having desired actions as an antibiotic substantially separable from undesirable effects on GI motility and the cardiac potassium channels such that the cardiac action potential is not prolonged and the QT interval on the surface EKG (electrocardiogram) is not increased, such that the erythromycin can be useful for more effective therapy of systemic infections. Also disclosed are methods for assaying the levels of such isomers present in the biological fluids.
专利号:WO-02064608-A1
优先权日:2000-11-29
标 题:Synthesis and separation of optically active isomers of erythromycin and their biological actions
发明人:SOMBERG JOHN C; RANADE VASANT
权利人:ACADEMIC PHARM INC; SOMBERG JOHN C; RANADE VASANT
摘要:The present invention provides methods for purifying and using optically active isomers of erythromycin as well as compositions comprising such optically active isomers. Such optically active isomers having desired actions as an antibiotic substantially separable from undesirable effects on GI motility and the cardiac potassium channels such that the cardiac action potential is not prolonged and the QT interval on the surface EKG (electrocardiogram) is not increased, such that the erythromycin can be useful for more effective therapy of systemic infections. Also disclosed are methods for assaying the levels of such isomers present in the biological fluids.
专利号:CA-1209987-A
优先权日:1981-11-27
标 题:Chemical process for the synthesis of macrolide antibiotics
专利号:FR-2517311-A1
优先权日:1981-11-27
标题 :CHEMICAL PROCESS FOR THE SYNTHESIS OF MACROLIDE ANTIBIOTICS
专利号:RU-2130936-C1
优先权日:1995-03-27
标 题:9a-azalide fragments of macrolide antibiotics of azalide class, method of their synthesis and intermediate compounds for their synthesis