CAS: 1848-84-6; 2-Ethyl-1H-Benzo[d]Imidazole

相似化合物

4414-88-4 5465-29-2 5851-43-4

上下游产品

CAS号95-54-5 邻苯二胺(OPD) | CAS号123-38-6 丙醛 | CAS号102-69-2 三正丙胺 | CAS号102-70-5 三烯丙基胺 | CAS号107-11-9 丙烯胺 | CAS号115-80-0 原丙酸三乙酯 | CAS号7424-54-6 3,5-二庚酮 | CAS号88-74-4 2-硝基苯胺 | CAS号14754-42-8 (9ci)-2-乙基-1-甲基... | CAS号2849-93-6 1H-苯并咪唑-2-羧酸 | CAS号20572-01-4 1-甲基-1H-苯并咪唑-2-羧酸 | CAS号6965-02-2 (2-苯并咪唑-2-基)-氢苯并咪唑 | CAS号744-38-7 N-(2-benzamidop... | CAS号64266-25-7 1H-Benzimidazol... | CAS号4061-42-1 2-[[6-[[2-(4-me... | CAS号39069-25-5 (9ci)-1-乙烯-2-乙基...

2-Cyano-1,3-Bis(Ethoxycarbonyl)-2,3-Dihydrobenzimidazole置于苯甲酸,Lithium Diisopropyl Amide体系中,用 四氢呋喃,正己烷 用作溶剂,化学反应 29.0H,反应生成2-乙基苯并咪唑
参考文献:Uff,Barrie C.; Ho,Yee-Ping; Burford,Donald L. W.,Journal Of Heterocyclic Chemistry,1987,Vol. 24,P. 1349-1351
标题:Uff,Barrie C.; Ho,Yee-Ping; Burford,Donald L. W.,Journal Of Heterocyclic Chemistry,1987,Vol. 24,P. 1349-1351

专利信息

专利号:US-2012328569-A1
优先权日:2010-03-02
标题:Inhibitors of hepatitis c virus ns5b polymerase
发明人：MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; SOLL RICHARD; LI PENG; PENG XUANJIA; WU HAO; NARJES FRANK; HABERMANN JOERG; KOCH UWE; LIU SHILAN
权利人:MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; SOLL RICHARD; LI PENG; PENG XUANJIA; WU HAO; NARJES FRANK; HABERMANN JOERG; KOCH UWE; LIU SHILAN
摘要:Disclosed are compounds of formula (I) that are used as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:US-11708320-B2
优先权日:2018-06-29
标 题:Environmentally-friendly hydroazidation of olefins
发明人：XU HAO
权利人:UNIV GEORGIA STATE RES FOUND
摘要:The present invention provides processes for the synthesis of organic azides, intermediates for the production thereof, and compositions related thereto.

专利号:US-2005249675-A1
优先权日:2003-06-19
标 题 :Mucin synthesis inhibitors
发明人：HUNG HSIAO-LING; CHELLQUIST ERIC; LEVITT ROY C; MCLANE MICHAEL
权利人:HUNG HSIAO-LING; CHELLQUIST ERIC; LEVITT ROY C; MCLANE MICHAEL
摘要:The claimed invention relates to methods of modulating mucin synthesis and the therapeutic application of compounds in controlling mucin over-production associated with diseases such as chronic obstructive pulmonary diseases (COPD) including asthma and chronic bronchitis, inflammatory lung diseases, cystic fibrosis and acute or chronic respiratory infectious diseases.

专利号:US-7345051-B2
优先权日:2000-01-31
标题 :Mucin synthesis inhibitors
发明人：ZHOU YUHONG; LEVITT ROY C; NICOLAIDES NICHOLAS C; JONES STEVE; MCLANE MIKE
权利人:GENAERA CORP
摘要:The claimed invention relates to methods of modulating mucin synthesis and the therapeutic application of compounds of Formula II in controlling mucin over-production associated with diseases such as chronic obstructive pulmonary diseases (COPD) including asthma and chronic bronchitis, inflammatory lung diseases, cystic fibrosis and acute or chronic respiratory infectious diseases. n nwhereinn X is S, N, O or CR; Y is CRR′, O, NR 6 , CRR′—CRR′ or CRâ•?CR; Z is NR 6 , O, S, CRR′ or CRR′—CRR′; R 1 -R 3 are independently selected from the group consisting of H, C 1 -C 8 alkyl, C 1 -C 8 alkoxy, amino, hydroxy, halosubstituted alky and halo; R 4 is n n n n n n n n n n n n n n n n n n n Q is CR, NR 6 or n n n n n n n n n n n n R 5 is H or benzyl; n R 6 is H, C 1 -C 8 alkyl, C 1 -C 8 alkoxy, OH or halo; and n R and R′ are independently H, C 1 -C 8 alkyl, C 1 -C 8 alkoxy, OH or halo,n nor a harmaceutically acceptable salt thereof.

专利号:US-8772301-B2
优先权日:2009-12-18
标题 :Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof
发明人：HARDY LARRY WENDELL; HEFFERNAN MICHELE L R; WU FRANK XINHE; SPEAR KERRY L; SARASWAT LAKSHMI D
权利人:HARDY LARRY WENDELL; HEFFERNAN MICHELE L R; WU FRANK XINHE; SPEAR KERRY L; SARASWAT LAKSHMI D; SUNOVION PHARMACEUTICALS INC
摘要:Provided herein are compounds and methods of synthesis thereof. The compounds set forth herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, neurodegenerative disorders, neuropsychiatric disorders, disorders of cognition, learning or memory, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds set forth herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.

专利号:US-10995078-B2
优先权日:2013-03-13
标 题:Compounds and compositions for inhibition of FASN
发明人：BAIR KENNETH W; LANCIA JR DAVID R; LI HONGBIN; LOCH JAMES; LU WEI; MARTIN MATTHEW W; MILLAN DAVID S; SCHILLER SHAWN E R; TEBBE MARK J
权利人:FORMA THERAPEUTICS INC
摘要:The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below: