CAS: 89913-60-0; 3-O-Acetyl-α-Boswellic Acid
该化合物是来自Boswellia serrata树树树脂的三叶类化合物,以其抗炎和治疗特性而著称,该化合物在-boswellic酸结构三处有一个乙酰组,这增加了其生物利用率和药理效应,其特点是复杂的四环结构,包括多环和有助于其生物活动的功能组. 3-O-Acetyl-boswellic 酸研究其治疗关节炎和其他炎性疾病的可能性,因为它可能抑制了阻燃性中间体.此外,该混合物还具有抗氧化性特性,有助于缓解细胞中的氧化性压力,该复合体通常在室温固态下发现,并且有机溶解剂中溶解.其安全性特征和临床应用中的功效继续成为研究课题,突出其在天然产品化学和药学中的重要性.
- 英文名称3-O-Acetyl-α-Boswellic Acid
- 中文名称乙酰基-α-乳香酸
- IUPAC名称(3R,4R,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-3-acetyloxy-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4-carboxylic acid
- 其它别名(3alpha,4beta)-3-(Acetyloxy)olean-12-en-23-oic acid; Acetyl-alpha-boswellic acid; alpha-Boswellic acid acetate
- CAS编号89913-60-0
- MFCD编号:MFCD03788772
- EINECS号:805-346-3
- FDA UNII编号:BIO9XQ683U
- 分子式:C32H50O4分子量:498.74
- 产品CID: 1929214
- 产品分类分析化学 → 标准品 → 分析标准品
物理性质
MSDS等安全信息
合成工艺路线路线简述
📜Alkaline Earth Salt Of/the/ Methylsulfuric Acid 反应生成 乙酰基-Alpha-乳香酸
参考文献:Trost,Annali Di Chimica Applicata,1937,Vol. 27,P. 178,185
标题:Trost,Annali Di Chimica Applicata,1937,Vol. 27,P. 178,185
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905399001-1,3-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2006234990-A1
优先权日:1999-04-30
标题 :Compositions of boswellic acids derived from Boswellia serrata gum resin, for treating lymphoproliferative and autoimmune conditions
发明人：MAJEED MUHAMMED; BADMAEV VLADIMIR
权利人:SAMI LABS LTD
摘要:A method of treatment of lymphoproliferative and autoimmune disorders with a new composition of four boswellic acids including β-boswellic acid, 3-O-acetyl-β-boswellic acid, 11-keto-β-boswellic acid, and 3-O-acetyl-11-keto-β-boswellic acid. Boswellic acids of invention have been obtained in a novel industrial process from the gum resin of Boswellia serrata tree, providing standardized composition which inhibits DNA, RNA and protein synthesis of the target cell without cytotoxic effects. The composition of invention provides advantage of irreversible cytostatic therapy, equivalent to biological effects of a cytotoxic therapy without killing body cells.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1002/mrc.1138
摘要:Belsner K, Büchele B, Werz U, Syrovets T, Simmet T. Structural analysis of pentacyclic triterpenes from the gum resin of Boswellia serrata by NMR spectroscopy. Magnetic Reson in Chemistry. 2003 Jan 07;41(2):115–22. doi: 10.1002/mrc.1138.
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