CAS: 503-09-3; 2-(Fluoromethyl)Oxirane

相似化合物

51594-55-9 60456-23-7 39443-66-8

上下游产品

epichlorohydrin 3-fluoropropene azobisisopropane 2-bromo-3-fluoropropan-1-ol1-fluoro-3-(methoxy)propan-2-ol (+/-)-α-(fluoromethyl)benzeneethanol Guajacyl-(2-hydroxy-3-fluor-propyl)-aether 1-Fluoro-3-phenoxypropan-2-ol

Alkaline Earth Salt Of/the/ Methylsulfuric Acid置于sodium Hydroxide,乙醚体系中,化学反应生成 环氧氟丙烷
参考文献:457.有机氟化合物.第九部分 氟丙酮和1:3-二氟丙酮的制备
标题:457.有机氟化合物.第九部分 氟丙酮和1:3-二氟丙酮的制备
摘要:
DOI:10.1039/jr9580002259

专利信息

专利号:US-5886190-A
优先权日:1993-10-04
标 题:Rapid synthesis and use of 18F-fluoromisonidazole and analogs
发明人：WALLACE SIDNEY; YANG DAVID J; CHERIF ABDALLAH
摘要:The present invention involves a rapid synthesis of 18F-FMISO and analogs thereof. New precursors such as 1-(2'-nitro-1'-imidazolyl)-2-0-acetyl-3-0-tosylpropanol, glycerol-1,3-ditosylate-2-0-acetylate, 1-(2'-nitro-1'-imidazolyl)-2,3-0-diacetyl-4-0-tosylbutanol and threitol 1,4-di-tosylate-2,3-0-diacetylate, are also important aspects of the invention. A further aspect of the invention is the development of a hydrophilic PET ligand to image tumor hypoxia. Erythrotosyl analogue of 2-nitroimidazone (Ts-ETNIM) was prepared from a mixture of 2-nitromidazole, ditosylthreitol and cesium carbonate at 60 DEG C. for 1 hr. Ts-ETNIM was isolated at 70% yield. [18F]fluoroerythronitroimidazole (FETNIM) was then prepared from Ts-ETNIM and K18F/kryptofix TM . The yield for [18F]FETNIM was 26-30% (60 min, decay corrected). Results of biodistribution and PET studies indicate that [18F]FETNIM has the potential to detect tumor hypoxia and is indicated to be less neurotoxic.

专利号:WO-2025042113-A1
优先权日:2023-08-18
标 题:Composition of synthesis reaction product of isosorbide-based epoxy compound, paint composition comprising same, and method for preparing isosorbide-based epoxy compound
发明人：LEE HYESEUNG; SHIM SUNWOO; LEE YUMI; NOH KYUNG HYUN; LEE SEJIN
权利人:KUK DO CHEMICAL CO LTD
摘要:The present invention relates to a composition of a synthesis reaction product of an isosorbide-based epoxy compound, a paint composition comprising same, and a method for preparing an isosorbide-based epoxy compound and, specifically, to a composition, with low viscosity and high purity, of a synthesis reaction product of an isosorbide-based epoxy compound, a paint composition comprising same, and a method for preparing an isosorbide-based epoxy compound with improved yield.

专利号:US-6986818-B2
优先权日:2000-06-02
标题 :Method for producing nanostructured metal-oxides
发明人：TILLOTSON THOMAS M; SIMPSON RANDALL L; HRUBESH LAWRENCE W; GASH ALEXANDER
权利人:UNIV CALIFORNIA
摘要:A synthetic route for producing nanostructure metal-oxide-based materials using sol-gel processing. This procedure employs the use of stable and inexpensive hydrated-metal inorganic salts and environmentally friendly solvents such as water and ethanol. The synthesis involves the dissolution of the metal salt in a solvent followed by the addition of a proton scavenger, which induces gel formation in a timely manner. Both critical point (supercritical extraction) and atmospheric (low temperature evaporation) drying may be employed to produce monolithic aerogels and xerogels, respectively. Using this method synthesis of metal-oxide nanostructured materials have been carried out using inorganic salts, such as of Fe 3+ , Cr 3+ , Al 3+ , Ga 3+ , In 3+ , Hf 4+ , Sn 4+ , Zr 4+ , Nb 5+ , W 6+ , Pr 3+ , Er 3+ , Nd 3+ , Ce 3+ , U 3+ and Y 3+ . The process is general and nanostructured metal-oxides from the following elements of the periodic table can be made: Groups 2 through 13, part of Group 14 (germanium, tin, lead), part of Group 15 (antimony, bismuth), part of Group 16 (polonium), and the lanthanides and actinides. The sol-gel processing allows for the addition of insoluble materials (e.g., metals or polymers) to the viscous sol, just before gelation, to produce a uniformly distributed nanocomposites upon gelation. As an example, energetic nanocomposites of Fe x O y gel with distributed Al metal are readily made. The compositions are stable, safe, and can be readily ignited to thermitic reaction.

专利号:WO-2015091558-A1
优先权日:2013-12-16
标 题 :Quinoline derivates as precursors of 18f-labelled radiotracers and radiolabelling method
发明人：THANING MIKKEL JACOB; WYNN DUNCAN GEORGE; FAIRWAY STEVEN MICHAEL; NAIRNE ROBERT JAMES; FURUMOTO SHOZO
权利人:GE HEALTHCARE LTD
摘要:The present invention relates to the field of radiopharmaceuticals for in vivo imaging, in particular to precursors for the preparation of 18 F-labelled tau imaging radiotracers. The invention provides alternative methods of preparation of such precursors, with fewer process steps. Also provided are protected quinoline intermediates useful in the synthesis, and methods of 18 F-radiofluorination using precursors prepared via the method of the invention.

专利号:US-11219887-B2
优先权日:2017-08-28
标 题 :Method for preparing organic zinc catalyst, organic zinc catalyst prepared by the method and method for preparing polyalkylene carbonate resin using the catalyst
发明人：BANG JUNGUP; PARK KYOSUNG; PARK SEUNG YOUNG; HWANG GYO HYUN; CHOI BYUNG HEE; KIM SUNG-KYOUNG; BANG YONGJU
权利人:LG CHEMICAL LTD
摘要:The disclosed relates to a method for preparing an organic zinc catalyst used in the synthesis of a polyalkylene carbonate resin, an organic zinc catalyst provided therefrom, and a method for preparing a polyalkylene carbonate resin using the catalyst. The organic zinc catalyst according to the present disclosure includes a predetermined amount of Zr on the surface through a simple process, and thus can exhibit improved catalytic activity as compared to a conventional catalyst in the polymerization process for preparing a polyalkylene carbonate resin.

专利号:US-6986819-B2
优先权日:2000-06-02
标 题:Metal-oxide-based energetic materials and synthesis thereof
发明人：TILLOTSON THOMAS M; SIMPSON RANDALL L; HRUBESH LAWRENCE W
权利人:UNIV CALIFORNIA
摘要:A method of preparing energetic metal-oxide-based energetic materials using sol-gel chemistry has been invented. The wet chemical sol-gel processing provides an improvement in both safety and performance. Essentially, a metal-oxide oxidizer skeletal structure is prepared from hydrolyzable metals (metal salts or metal alkoxides) with fuel added to the sol prior to gelation or synthesized within the porosity metal-oxide gel matrix. With metal salt precursors a proton scavenger is used to destabilize the sol and induce gelation. With metal alkoxide precursors standard well-known sol-gel hydrolysis and condensation reactions are used. Drying is done by standard sol-gel practices, either by a slow evaporation of the liquid residing within the pores to produce a high density solid nanocomposite, or by supercritical extraction to produce a lower density, high porous nanocomposite. Other ingredients may be added to this basic nanostructure to change physical and chemical properties, which include organic constituents for binders or gas generators during reactions, burn rate modifiers, or spectral emitters.