CAS: 22927-13-5; 2-Ethylbenzaldehyde

该化合物是一种芳香甲醚,其特征是附于甲苯环的乙基组,与甲苯相邻,其分子分子配方为C9H10O,具有独特的甜味,花粉味,在香味工业中有用.该化合物一般没有色素,在室内温度下不会苍白黄色液体,而且沸点相对较低,便于挥发.有机溶剂中的溶液是好的,而由于其水分芳香结构,其溶液在水中的溶性有限. 2-乙基苯甲醚可参与各种典型的甲醚化学反应,包括氧化和凝聚反应.该物质还用作有机合成的中间体,可以用作更复杂的分子的建筑块.在处理该化合物时,应注意安全防范措施,因为它可能会对皮肤和眼睛造成刺激.

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CAS号1973-22-4 1-溴-2-乙基苯 | CAS号68-12-2 N,N-二甲基甲酰胺 | CAS号38846-64-9 2-乙炔苯甲醛 | CAS号21450-63-5 2-ETHYLPHENYLMA... | CAS号4433-63-0 乙基硼酸 | CAS号6630-33-7 2-溴苯甲醛 | CAS号97-94-9 三乙基硼 | CAS号84761-77-3 trifuoro-methan... | CAS号201230-82-2 carbon monoxide | CAS号18282-40-1 1-乙基-2-碘苯 | CAS号103988-23-4 3-(2-ETHYL-PHEN... | CAS号1467-06-7 1-(chloromethyl... | CAS号95-13-6 茚 | CAS号28362-76-7 Benzeneacetalde... | CAS号767-90-8 邻乙基苯甲醇 | CAS号102-93-2 3-苯基丙酰胺 | CAS号2114-00-3 2-溴苯丙酮 | CAS号74533-20-3 2-(2-乙基苯基)乙腈 | CAS号68913-17-7 8-methylbicyclo... | CAS号57825-29-3 1-(bromomethyl)...

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    专利信息


    专利号:US-9597327-B2
    优先权日:2005-05-25
    标 题:Synthesis of (R)-N-methylnaltrexone
    发明人:DOSHAN HAROLD D; PEREZ JULIO
    权利人:PROGENICS PHARM INC
    摘要:This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.

    专利号:WO-0146142-A1
    优先权日:1999-12-20
    标题:A process for the regioselective synthesis of 2,2-dialkyl-4-substituted piperidines
    发明人:HEATH PERRY CLARK
    权利人:LILLY CO ELI; HEATH PERRY CLARK
    摘要:The present invention provides a process for preparing a compound of formula (I): wherein R?1 and R2¿ each independently represent C¿1?-C4 alkyl; and X represents an alkyl, alkenyl, cycloalkyl, aryl, substituted aryl, heterocycle, or substituted heterocycle, comprising treating a compound of formula (II): wherein Q represents Cl or Br, with a suitable base followed by addition of a suitable Lewis acid and addition of a compound of formula R?-M+¿ wherein M+ is a suitable cation.

    专利号:US-4292249-A
    优先权日:1979-02-15
    标题:25-Hydroxy-24-oxocholestane derivatives and preparation thereof
    发明人:NISHIKAWA OSAMU; ISHIMARU KENJI; TAKESHITA TORU; TSURUTA HIDEKI
    权利人:TEIJIN LTD
    摘要:This invention relates to novel 25-hydroxy-24-oxocholestane derivatives and a process for preparing them. The novel 25-hydroxy-24-oxocholestane derivatives of this invention can easily be converted to 24,25-dihydroxycholecalciferol or 1 alpha ,24,25-trihydroxycholecalciferol which is known as useful for medicine controlling the calcium metabolism of warm-blooded animals. Moreover, 25-hydroxy-24-oxocholestane derivatives can be converted to novel 25-hydroxy-24-oxocholecalciferol expressed by the following formula and novel 1 alpha ,25-dihydroxy-24-oxocholecalciferol of the formula which are useful for medicine. The new 25-hydroxy-24-oxocholestane derivatives in the present invention are very useful as the intermediates for the synthesis of a variety of active vitamin D3.

    专利号:US-7674904-B2
    优先权日:2005-05-25
    标 题 :Synthesis of R-N-methylnaltrexone

    专利号:US-2007099946-A1
    优先权日:2005-05-25
    标 题:Synthesis of R-N-methylnaltrexone

    专利号:US-4035405-A
    优先权日:1976-07-09
    标题 :Novel synthesis for preparing the hydrochloride salt of selected catecholamine derivatives
    发明人:BODOR NICOLAE S; YUAN SUN-SHINE
    权利人:INTERX RESEARCH CORP
    摘要:Compounds of the formula: ##STR1## wherein R represents a straight or branched C 1 -C 5 alkyl group; and R 1 in each occurrence represents an acyl member which is alkanoyl having 1-22 carbon atoms, alkenoyl having one or two double bonds and having 4-22 carbon atoms, ##STR2## having a total of 4-10 carbon atoms of which 3-7 are ring carbon atoms in cycloalkyl and wherein n is zero, one, or two, phenoxyacetyl, naphthalenecarbonyl, pyridinecarbonyl, ##STR3## wherein n is zero, one or two and phenyl is unsubstituted or is substituted by 1-3 alkyl having 1-4 carbon atoms, alkoxy having 1-4 carbon atoms, halo, trifluoromethyl, dialkylamino having 2-8 carbon atoms, or alkanoylamino having 1-6 carbon atoms groups; are prepared in substantial purity and yield, using as the chloride ion donor, cesium chloride (CsCl). n The compounds prepared by the process claimed herein exhibit sympathomimetic activity and are thus useful in eliciting sympathomimetic responses in warm-blooded animals, e.g., reduction in intraocular pressure, miosis, mydriasis, bronchodilation, etc.
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    主要参考文献

    [参考文献]: Mingzhang Gao, Et Al. Synthesis Of Carbon-11 Labeled 1-(3,4-Dimethoxybenzyl)-2,2-Dimethyl-1,2,3,4-Tetrahydroisoquinolinium Derivatives As New Potential Pet Skca Channel Imaging Agents. Appl Radiat Isot. 2008 Feb;66(2):194-202.

    合成参考文献


    摘要:Goldfuss, B., Science of Synthesis: C-1 Building Blocks in Organic Synthesis, (2013) 1, 429.
    参考文献:10.1007/bf00245162
    摘要:Kataoka M, Shimizu S, Yamada H. Distribution and immunological characterization of microbial aldehyde reductases. Arch Microbiol. 1992;157(3):279–83. doi: 10.1007/bf00245162.
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