CAS: 21594-52-5; 6-Bromo-3H-Oxazolo[4,5-B]Pyridin-2-One

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60832-72-6 1784534-06-0 35570-68-4

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N-(3-羟基吡啶-2-基)氨基甲酸乙酯置于n-溴代丁二酰亚胺(Nbs)体系中,用 二苯醚,乙腈 用作溶剂,化学反应 5.0H,反应生成6-溴-3H-恶唑并[4,5-B]吡啶-2-酮
参考文献: Pyrimidine And Triazine Derivatives And Their Use As Axl Inhibitors[fr] Dérivés De Pyrimidine Et De Triazine,Et Leur Utilisation Comme Inhibiteurs D'Axl
标题: Pyrimidine And Triazine Derivatives And Their Use As Axl Inhibitors[fr] Dérivés De Pyrimidine Et De Triazine,Et Leur Utilisation Comme Inhibiteurs D'Axl
摘要:公式(I)的化合物: (I) 这些化合物的制备方法,包含这些化合物的组合物,以及这些化合物的用途.

专利信息

专利号:US-8785632-B2
优先权日:2004-08-26
标 题:Enantiomerically pure aminoheteroaryl compounds as protein kinase inhibitors
发明人：CUI JINGRONG JEAN; FUNK LEE ANDREW; JIA LEI; KUNG PEI-PEI; MENG JERRY JIALUN; NAMBU MITCHELL DAVID; PAIRISH MASON ALAN; SHEN HONG; TRAN-DUBE MICHELLE
权利人:CUI JINGRONG JEAN; FUNK LEE ANDREW; JIA LEI; KUNG PEI-PEI; MENG JERRY JIALUN; NAMBU MITCHELL DAVID; PAIRISH MASON ALAN; SHEN HONG; TRAN-DUBE MICHELLE; AGOURON PHARMA; PFIZER
摘要:Enantiomerically pure compound of formula 1 n nare provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.

专利号:US-2006178374-A1
优先权日:2004-08-26
标 题 :Aminoheteroaryl compounds as protein kinase inhibitors
发明人：CUI JINGRONG J; FUNK LEE A; JIA LEI; KUNG PEI-PEI; MENG JERRY J; NAMBU MITCHELL D; PAIRISH MASON A; SHEN HONG; TRAN-DUBE MICHELLE
权利人:AGOURON PHARMA
摘要:Aminoheteroaryl compounds are provided, as well as methods for their synthesis and use. Preferred compounds are potent inhibitors of the c-Met protein kinase, and are useful in the treatment of abnormal cell growth disorders, such as cancers.