CAS: 16932-44-8; 2-Iodo-1,3-Dimethoxybenzene

相似化合物

20469-63-0 2510-49-8 41046-70-2

上下游产品

2,6-dimethoxyaniline (2,6-dimethoxyphenyl)lithium 1,2,3-trimethoxybenzene 2-(trimethylsilyl)-1,3-dimethoxybenzene 1,3-dimethoxy-2-phenylsulfanylbenzene 2,2',6,6'-tetramethoxydiphenyl sulfide 2,2',6'-Trimethoxy-5-methoxycarbonyl-biphenyl tris(2,6-dimethoxyphenyl)amine

📜2,6-二甲氧基苯硼酸置于n-碘代丁二酰亚胺体系中,用 乙腈 用作溶剂,化学反应 14.0H,以84%的收率获得2-碘-1,3-二甲氧基苯
参考文献:芳基硼酸与 N-卤代琥珀酰亚胺 Ipso 取代制备卤代芳烃
标题:芳基硼酸与 N-卤代琥珀酰亚胺 Ipso 取代制备卤代芳烃
摘要:芳基和杂芳基硼酸与 N-碘代琥珀酰亚胺和 N-溴代琥珀酰亚胺反应,以非常好至极好的收率获得相应的碘和溴芳烃.该反应通常具有高度的区域选择性,并且仅产生 Ipso 取代的产物.芳基硼酸酯的反应类似,但不太容易.最近有报道称,烯基硼酸可以通过与 N-卤代琥珀酰亚胺反应转化为烯基卤化物.1 该反应被认为是通过硼活化/直接置换机制进行的,提供几何纯的产品,并保留构型.在此我们报告了芳基硼酸到相应卤代芳烃的类似转化.芳基硼酸 2 易于获得且易于处理的化合物,最近它们已成为有机合成中重要的底物,作为 Suzuki 偶联反应中的芳基供体.3 它们的反应性通常低于烯基硼酸,并且预计不会通过加成/消除机制与 N-卤代琥珀酰亚胺反应.卤代芳烃是有价值的合成中间体,已开发出各种制备方法.虽然亲电芳香卤化在制备氯芳烃和溴芳烃方面效果很好,但用碘直接碘化芳烃通常是不可行的4,并且已经开发了许多不同的制备碘芳烃的方法
Doi:10.1055/s-1998-1614

专利信息

专利号:US-8604213-B2
优先权日:2008-10-21
标 题 :Fluorination of aromatic ring systems
发明人：DIMAGNO STEPHEN
权利人:DIMAGNO STEPHEN; NUTECH VENTURES
摘要:This disclosure relates to reagents and methods useful in the synthesis of aryl fluorides, for example, in the preparation of 18 F labeled radiotracers. The reagents and methods provided herein may be used to access a broad range of compounds, including aromatic compounds, heteroaromatic compounds, amino acids, nucleotides, and synthetic compounds.

专利号:US-9302990-B2
优先权日:2008-10-21
标 题 :Fluorination of aromatic ring systems
发明人：DIMAGNO STEPHEN GREGORY
权利人:DIMAGNO STEPHEN GREGORY; NUTECH VENTURES
摘要:This disclosure relates to reagents and methods useful in the synthesis of aryl fluorides, for example, in the preparation of 18 F labeled radiotracers. The reagents and methods provided herein may be used to access a broad range of compounds, including aromatic compounds, heteroaromatic compounds, amino acids, nucleotides, and synthetic compounds.

专利号:CN-113087689-A
优先权日:2021-03-10
标题 :A Facile Synthesis of 5-Amino-γ-Lactone Derivatives

专利号:CN-113087689-B
优先权日:2021-03-10
标题:A simple synthesis method of 5-amino-γ-lactone derivatives