CAS: 16574-43-9; 2',7'-Dibromo-3',4',5',6'-Tetrahydroxyspiro[benzo[c][1,2]Oxathiole-3,9'-Xanthene] 1,1-Dioxide

该化合物是一种合成染料和对pH敏感的指标,通常用于分析化学,在pH值范围从4.8到6.2之间显示出一种明显的颜色变化,从黄色到红色,对酸基乳乳液和光谱光谱分析很有价值.该化合物因其有选择性的染色特性,在探测铝,和稀土元素等金属离子的复合性乳液中特别有用.其高的摩尔吸收能确保追踪金属探测的敏感度.Bromopyrogallol 红色还用于生物化学化验,在显微镜中用作污渍剂.该染料在标准实验室条件下稳定,在水溶和酒精溶液溶液中很容易溶解.

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    专利信息


    专利号:US-2022233673-A1
    优先权日:2019-06-04
    标 题:METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STxB) MONOMERS AND OLIGOMERS, AND USES THEREOF
    发明人:BILLET ANNE; SCHMIDT FRÉDÉRIC; JOHANNES LUDGER; SERVENT DENIS; MOURIER GILLES; TARTOUR ÉRIC; KAY MICHAEL; FULCHER JAMES M
    权利人:INST CURIE; CENTRE NAT RECH SCIENT; INST NAT SANTE RECH MED; COMMISSARIAT A LENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES CEA; APHP ASSIST PUBLIQUE HOPITAUX DE PARIS; UNIV PARIS; UNIV OF UTAH RESEARCH FOUDATION; UNIV UTAH RES FOUND
    摘要:A method of producing a monomer of a Shiga toxin B-subunit (STxB) protein or of a variant thereof by peptide chemical synthesis, as well as to a method of producing a pentamer of the STxB protein or of the variant thereof. The methods are particularly advantageous as they overcome major issues typically observed in peptide chemical synthesis, including solubility and purity issues.

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    合成参考文献


    参考文献:10.1007/978-3-642-68992-5_6
    摘要:Parker GA. Colorimetric Methods. 1983. In: Analytical Chemistry of Molybdenum.
    参考文献:10.1007/978-3-642-70516-8_4
    参考文献:10.1007/978-3-642-77477-5_4
    摘要:Perkampus H. Analytical Applications of UV-VIS Spectroscopy. 1992. In: UV-VIS Spectroscopy and Its Applications.
    参考文献:10.2478/s11532-008-0095-3
    摘要:Liu H, Wen Y, Luan F, Gao Y, Guo Y, Xie Z, Hu Z. Quantitative structure-property relationship study on the determination of binding constant by fluorescence quenching. 2009 Mar 01;7(1):59–65. doi: 10.2478/s11532-008-0095-3.
    参考文献:10.1007/s10661-008-0654-2
    摘要:Ramachandraiah C, Rajesh Kumar J, Adinarayana Reddy S, Lee J, Varada Reddy A. Development of a highly sensitive and selective method for extractive spectrophotometric determination of aluminum(III) from environmental matrices, synthetic mixtures, and alloys using orthohydroxypropiophenoneisonicotinoylhydrazone. Environmental Monitoring and Assessment. 2008 Dec 05;160(1-4):23. doi: 10.1007/s10661-008-0654-2.
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