CAS: 13188-89-1; H-D-Asp(Obzl)-Oh

相似化合物

2177-63-1 3479-47-8 51186-58-4

上下游产品

4-benzyl B°C-D-aspartate (2R)-aspartic acid benzyl alcohol4-benzyl B°C-D-aspartate N-acetyl-D-aspartic acid β-benzyl ester (R)-2-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-hydroxy-propionylamino)-3-(4-hydroxy-phenyl)-propionylamino]-succinic acid 4-benzyl ester N-[(R)-3-dodecanoyloxytetradecanoyl]-D-aspartic acid β-benzyl ester

专利信息

专利号:US-2025091989-A1
优先权日:2023-09-19
标 题 :Small molecule protein synthesis modulators
发明人：GYGI DAVID; BAHMANYAR SOGOLE SAMI; HAMANN LAWRENCE
权利人:INTERDICT BIO INC
摘要:The present disclosure provides compounds of the formulae herein (e.g., Formula (I)), and pharmaceutically acceptable salts thereof, which are useful for modulating protein synthesis (e.g., modulating synthesis of BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D). The present disclosure also provides pharmaceutical compositions and kits comprising the compounds, or pharmaceutically acceptable salts thereof, and methods of treating or preventing diseases or disorders (e.g., diseases or disorders associated with BCL-2, MYC, CCND1, MCL-1, ALK, KRAS-G12D) by administering to a subject in need thereof the compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof.

专利号:US-2008248097-A1
优先权日:2007-02-26
标题 :Polymeric micelles for combination drug delivery
发明人：KWON GLEN S; BAE YOUNSOO; ALANI ADAM WG
权利人:KWON GLEN S; BAE YOUNSOO; ALANI ADAM WG
摘要:The invention provides block polymers, micelles, and micelle formulations for combination drug therapy. Polyamide block polymers, such as those of formulas I and II are useful, for example, for preparation of mixed drug micelles, including simply mixed micelles, physically mixed micelles, and chemically mixed micelles. The invention further provides methods of treating cancer, and inhibiting and killing cancer cells. Also provided are methods for the preparation of polymer drug conjugates and intermediates for their synthesis.

专利号:CN-109535225-A
优先权日:2018-11-22
标 题:A kind of compound and its synthesis method and application