CAS: 122-28-1; N-(3-Nitrophenyl)Acetamide

该化合物是一种有机化合物,其特征为氨化功能组和硝基苯替代物,其性质一般是固体的,往往是晶状的,由于硝基化合物组的存在,其黄色颜色为人所知.该化合物在乙醇和丙酮等有机溶剂中溶解,但水溶解性有限.N-(3-硝基苯)乙酰胺主要用于有机合成,并作为生产各种药品和农用化学品的一个中间体.其结构中含有一个代孕基体的苯环,该代之元体位置可影响其再活性和生物活动.乙酰胺组的存在有助于其参与各种化学反应的能力,包括核生殖器替代和混合反应.与许多硝基化合物一样,它可能具有毒性,应在实验室环境中谨慎处理.

结构式图片

相似化合物

102-28-3 17090-15-2 104-04-1

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

N-acetyl-N-phenylacetamide is°Cyanic acid (3-nitro-phenyl) ester acetic anhydride 3-nitrobenzoyl azide 3-nitro-N-phenylaniline 3,4-dinitroacetanilide 2,3,4,6-tetranitroaniline 5-(N-acetylamino)-2-bromonitrobenzene

合成工艺路线路线简述

  • 合成目标产物 3'-Nitroacetanilide 主要起始原料 Acetic Acid And 3-Nitroaniline
  • (文献来源)合成步骤主要原料 Acetic Acid 和 3-Nitroaniline
📜(4-氨基苯)羧酸乙酯置于sodium Hydroxide,Sodium Nitrate,硫酸体系中,用 乙醇,溶剂黄146 用作溶剂,化学反应 4.0H,反应生成间硝基乙酰替苯胺
参考文献:Rosevear,Judi; Wilshire,John F. K.,Australian Journal Of Chemistry,1985,Vol. 38,# 5,P. 723-733
标题:Rosevear,Judi; Wilshire,John F. K.,Australian Journal Of Chemistry,1985,Vol. 38,# 5,P. 723-733

海关参考信息

专利信息


专利号:US-2005119332-A1
优先权日:1998-03-12
标 题 :Substituted thiophene compounds as modulators of protein tyrosine phosphatases (PTPases)
发明人:JEPPESEN LONE; ANDERSEN HENRIK S; OLSEN OLE H; JUDGE LUKE M; HOLSWORTH DANIEL D; BAKIR FARID; AXE FRANK U; GE YU
摘要:The present invention provides novel compounds of formula 1a, n nnovel compositions, methods of their use, and methods of their manufacture, where such compounds are pharmacologically useful inhibitors of Protein Tyrosine Phosphatases (PTPase's) such as PTP1B, CD45, SHP-1, SHP-2, PTPα, LAR and HePTP or the like. The compounds are useful in the treatment of type I diabetes, type II diabetes, impaired glucose tolerance, insulin resistance, obesity, immune dysfunctions including autoimmunity diseases with dysfunctions of the coagulation system, allergic diseases including asthma, osteoporosis, proliferative disorders including cancer and psoriasis, diseases with decreased or increased synthesis or effects of growth hormone, diseases with decreased or increased synthesis of hormones or cytokines that regulate the release of/or response to growth hormone, diseases of the brain including Alzheimer's disease and schizophrenia, and infectious diseases.

专利号:RU-2201917-C2
优先权日:2001-04-27
标 题 :Method of synthesis of 3-nitrodiphenylamine

专利号:CN-117776927-A
优先权日:2023-04-13
标题 :A kind of synthesis method of m-nitrodiphenylamine compounds

专利号:CN-107880037-A
优先权日:2017-09-27
标题:A kind of synthesis method and application of 2-oxo-2-(arylaniline) ethyl substituted moxifloxacin series compounds

专利号:CN-101045692-A
优先权日:2007-04-30
标 题 :A green synthesis process of 2-alkoxy-5-acetamidoaniline

专利号:CN-100593535-C
优先权日:2007-04-30
标题 :A green synthesis process of 2-alkoxy-5-acetamidoaniline

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

主要参考文献

[参考文献]: P C Adams, Et Al. The Absorption And First-Pass Metabolism Of [14C]-1,3-Dinitrobenzene In The Isolated Vascularly Perfused Rat Small Intestine. Biopharm Drug Dispos. 1996 Nov;17(8):675-98.

合成参考文献


摘要:Sambiagio, C.; Maes, B. U. W., Science of Synthesis: Cross-Dehydrogenative Coupling, (2023) nan, 134.
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