专利号:US-9469614-B2 优先权日:2011-10-27 标 题:Synthesis of triazolopyrimidine compounds 发明人:ZUPANCIC BORUT; MARAS NENAD; STERK DAMJAN 权利人:LEK PHARMACEUTICALS 摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.
专利号:EP-2586773-A1 优先权日:2011-10-27 标题 :Synthesis of Triazolopyrimidine Compounds 权利人:LEK PHARMACEUTICALS 摘要:The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.
专利号:US-4734495-A 优先权日:1985-07-17 标 题 :Process and intermediates for beta-lactam antibiotics 发明人:EVANS DAVID A; SJOGREN ERIC B 权利人:HARVARD COLLEGE 摘要:1-Benzyl(or substituted benzyl)-3β-[4(S)-aryloxazolidin-2-one-3-yl]-4β-(2-arylvinyl)azetidin-2-ones are provided via cycloaddition of a 4(S)-aryloxazolidin-2-one-3-ylacetyl halide and an imine formed with a benzylamine and a 3-arylacrolein, e.g. cinnamaldehyde. The azetidinones are useful chiral intermediates in an asymmetric synthesis of 1-carba(1-dethia)-3-hydroxy-3-cephem-4-carboxylic acids and esters and to monocyclic β-lactam antibiotics.
专利号:US-4870169-A 优先权日:1985-07-17 标 题:Intermediates for beta-lactam antibiotics 发明人:EVANS DAVID A; SJOGREN ERIC B 权利人:HARVARD COLLEGE 摘要:1-Benzyl(or substituted benzyl)-3β-[4(S)-aryloxazolidin-2-one-3-yl]-4β-(2-arylvinyl)azetidin-2-ones are provided via cycloaddition of a 4(S)-aryloxazolidin-2-one-3-ylacetyl halide and an imine formed with a benzylamine and a 3-arylacrolein, e.g. cinnamaldehyde. The azetidinones are useful chiral intermediates in an asymmetric synthesis of 1-carba(1-dethia)-3-hydroxy-3-cephem-4-carboxylic acids and esters and to monocyclic β-lactam antibiotics.
专利号:CA-2852652-A1 优先权日:2011-10-27 标题 :Synthesis of triazolopyrimidine compounds
专利号:EP-2771326-A1 优先权日:2011-10-27 标题:Synthesis of triazolopyrimidine compounds