CAS: 10534-89-1; Hexaamminecobalt(Iii)Chloride

该化合物是一个由钴(III)中心组成的协调综合体,环绕着6个氨皮和3个氯化反射器,该综合体具有高度稳定性和明确的八面形几何特征,在协调化学研究和催化方面很有价值.它作为合成其他钴复合体的前体,并因其红氧化作用特性而用于电化学研究.该综合体的晶体结构和水溶性增强了其在实验室应用中的效用.其一贯的纯度和再活动使它成为无机合成和物质科学研究的可靠选择.

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欧盟法规

ECHA物质C&L通报REACH预注册

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hydrogenchloride ammonia pentaaminechlor°Cobalt(III) dichloride cobalt(II) chlorideα-triglycinecobalt(III) α-trialaninecobalt(III) {Colc3}

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    专利信息


    专利号:US-11007514-B2
    优先权日:2019-04-05
    标 题 :Ammonia facilitated cation loading of zeolite catalysts
    发明人:GOFFE RANDAL A
    权利人:PACCAR INC
    摘要:The present disclosure features a high metal cation content zeolite-based binary catalyst (e.g., a high copper and/or iron content zeolite-based binary catalyst, where the zeolite can be a chabazite) for NO x reduction, having relatively low N 2 O make, and having low corresponding metal oxide content; where the metal in the metal oxide corresponds to the metal of the metal cation. The present disclosure also describes the synthesis of the zeolite-based binary catalyst having high metal cation content.

    专利号:US-12428659-B2
    优先权日:2020-05-28
    标 题 :De novo polynucleotide synthesis with substrate-bound polymerase
    发明人:NGUYEN BICHLIEN; SMITH JAKE; STRAUSS KARIN
    权利人:MICROSOFT TECHNOLOGY LICENSING LLC
    摘要:De novo polynucleotide synthesis is performed with a substrate-bound polymerase. The polymerase is attached to a solid substrate such as a microelectrode array. The polymerase adds nucleotides to growing polynucleotides strands that are also attached to the solid substrate. Spatial control of polymerase activity is achieved by changing the rate of nucleotide polymerization at selected locations on the surface of the solid substrate. The rate of polymerization is changed by inhibiting or promoting activity of the polymerase. In some implementations, activation of electrodes in the microelectrode array changes the rate of nucleotide polymerization. Nucleotides are added to the growing polynucleotide strands at areas where the polymerase is active. By varying the locations where the substrate-bound polymerase is active and the species of nucleotide added, a population of polynucleotides with different, arbitrary sequences is synthesized on the surface of the solid substrate.

    专利号:US-12398412-B2
    优先权日:2019-08-16
    标题 :Regulation of polymerase using cofactor oxidation states
    发明人:NGUYEN BICHLIEN HOANG
    权利人:MICROSOFT TECHNOLOGY LICENSING LLC
    摘要:Polynucleotide synthesis performed with a template independent polymerase such as terminal deoxynucleotidyl transferase (TdT) is regulated by controlling the oxidation state of a metal cofactor. The oxidation state of the metal cofactor is changed to +2, thus activating the polymerase, by applying a voltage with electrodes or by introducing a chemical redox reagent. Addressable polynucleotide synthesis creates polynucleotides with different arbitrary sequences through use of spatial control of cofactor oxidation states to add nucleotides only at selected locations on an array. Control of metal oxidation states is regulated by selective activation of a microelectrode array, controlled addition of redox reagents to specific locations on the array, or controlled activation of photocatalysts at specific locations on the array. Scavengers in solution prevent cofactors distant from the selected locations from catalyzing polymerase activity and thereby maintain the localized effect of polymerase activation.

    专利号:US-6087332-A
    优先权日:1997-12-23
    标 题 :Streptokinase derivatives with high affinity for activated platelets and methods of their production and use in thrombolytic therapy
    发明人:GALLER LAWRENCE ISAAC
    摘要:Streptokinase derivatives having platelet glycoprotein binding domains adjacent to the termini of the streptokinase sequence. These derivatives produce higher local concentrations of plasmin in vivo as compared to unmodified streptokinase. Certain of the derivatives have high affinity for the GPIIB/IIIA receptor and low affinity for the fibronectin and vitronectin receptors. Others have substantially equivalent affinity for all three receptors. The derivatives are useful in treating thromboembolic disorders. The streptokinase derivatives can be made by recombinant techniques or by chemical synthesis or conjugation.

    专利号:US-5789206-A
    优先权日:1995-07-07
    标 题 :Method for ligating adaptors to nucleic acids which methods are useful for obtaining the ends of genes
    发明人:TAVTIGIAN SEAN V; STONE STEVEN; JIANG PING; KAMB ALEXANDER
    权利人:MYRIAD GENETICS INC
    摘要:The present invention is directed to cloning the ends of genes. Traditionally it has been very difficult to recover the 5' end of a gene. The present invention greatly eases this problem. The invention is a variation on RACE and uses a combination of techniques. Specific genes are purified by using three enrichment steps--1) a polymerase chain reaction, 2) a hybrid capture step, and 3) a second polymerase chain reaction. The inclusion of the hybrid capture step results in a greater enrichment than occurs with RACE. The ends of the gene are retained by use of a novel technique of attaching adaptors at the ends of the nucleic. The 5' end of the gene is conserved by preparing a first strand of cDNA and ligating to this an adaptor which is partially double stranded wherein the overhang or single stranded region of the adaptor is degenerate which allows for a fraction of the adaptor population to hybridize with the first strand of cDNA at the 3' end of the cDNA. This hybridization holds the adaptor in conjunction with the cDNA during the ligation step thereby resulting in a highly efficient ligation. The unique portion of the adaptor is used to design an oligomer to prime the second strand synthesis. None of the 5' sequence is lost in this method thereby allowing for a greater possibility of recovering the extreme 5' end of the gene.

    专利号:US-9668514-B2
    优先权日:2004-10-25
    标 题:Synthesis and incorporation of high-temperature ammonia-release agent in lit-end cigarettes
    发明人:FOURNIER JAY A; PAINE JOHN B; FERNANDEZ DOUGLAS A
    权利人:PHILIP MORRIS USA INC
    摘要:A tobacco smoking mixture and/or a cigarette wrapper with high-temperature ammonia-release agents therein are provided, wherein the high-temperature ammonia-release agents are present in an amount effective to reduce the cytotoxicity of gas phase or particulate matter formed during smoking of the cigarette. The high-temperature ammonia-release agents are capable of reducing the cytotoxicity of gas phase or particulate matter by evolving ammonia at temperatures greater than about 200° C., wherein the ammonia can interact with the particulate matter. Additionally, the high-temperature ammonia-release agents can be formed by heating an aqueous mixture of an iron precursor compound, an ammonia source compound and an acid.

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    主要参考文献

    [参考文献]: G Soslau, Et Al. Methylation And Restriction Endonuclease Cleavage Of Linear Z-Dna In The Presence Of Hexamminecobalt (Iii) Ions. Nucleic Acids Res. 1986 Sep 25;14(18):7237-52.
    [参考文献]: Isabelle Bougie, Et Al. Metal Ion-Binding Studies Highlight Important Differences Between Flaviviral Rna Polymerases. Biochim Biophys Acta. 2009 Jan;1794(1):50-60.
    [参考文献]: J A Murray, Et Al. Hcc Ligation: Rapid And Specific Dna Construction With Blunt Ended Dna Fragments. Nucleic Acids Res. 1986 Dec 22;14(24):10118.
    [参考文献]: J D Rush, Et Al. The Electron-Transfer Site Of Spinach Plastocyanin. Biochemistry. 1988 Aug 9;27(16):5876-84.
    [参考文献]: Meredith Newby Lambert, Et Al. Solution Probing Of Metal Ion Binding By Helix 27 From Escherichia Coli 16S Rrna. Rna. 2005 Nov;11(11):1688-700.

    合成参考文献


    参考文献:10.1007/s00232-003-0614-2
    摘要:Castelli L, Tanzi F, Taglietti V, Magistretti J. Cu 2+ , Co 2+ , and Mn 2+ Modify the Gating Kinetics of High-Voltage-Activated Ca 2+ Channels in Rat Palaeocortical Neurons. Journal of Membrane Biology. 2003 Oct 01;195(3):121–36. doi: 10.1007/s00232-003-0614-2.
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