CAS: 7443-70-1; Rel-(1R,2S)-2-Methylcyclohexanol

相似化合物

583-60-8 7443-52-9 15963-35-6

上下游产品

CAS号583-60-8 2-甲基环己酮

3-甲基-1-环己烯 在 过氧乙酸,三(五氟苯基)硼烷,Sodium Acetate,Potassium Bromide体系中,用 二氯甲烷,溶剂黄146作为反应溶剂,获得 Cis-2-Methylcyclohexanol
参考文献:高效b(C(6)F(5))(3)催化的烯烃氢化硅烷化.
标题:高效b(C(6)F(5))(3)催化的烯烃氢化硅烷化.
摘要:已经开发了一种方便高效的烯烃路易斯酸催化的反选择氢化硅烷化方法.该新方案的机理是通过在c = C键上直接添加甲硅烷基型物质,然后用硼键合的氢化物捕集所得的碳正离子而起作用.使用这种氢化硅烷化方法可以有效地制备许多在硅原子上同时具有芳基和烷基的不同取代的硅烷.在该反应中使用含芳基的氢硅烷的可能性为通过反式选择性氢化硅烷化/ Tamao-Fleming氧化顺序(与现有的顺式选择性氢硼化/氧化方案互补)合成醇提供了广泛的能力.
Doi:10.1021/Jo016279Z

专利信息

专利号:US-6509506-B1
优先权日:1997-05-21
标 题 :Two step synthesis of D- and L- α-amino acids and D- and L- α-amino aldehydes
发明人：SHARPLESS K BARRY; LI GUIGEN
权利人:SCRIPPS RESEARCH INST
摘要:D- and L- α-amino acids and D- and L-α-amino aldehydes are synthesized from olefin substrates in two steps. The first step is a catalyzed asymmetric aminohydroxylation addition reaction to the olefin substrate. The addition reaction is catalyzed by osmium and is co-catalyzed by chiral ligands. The chiral ligands, in addition to being co-catalysts with the osmium, also serve to direct the addition reaction regioselectively and enantioselectively, divalent ligands are preferred over monovalent ligands because of their enhanced regio-and enantio-selectivity. As an oxidant nitrogen source for the addition reaction, either a carbamate or sulfonamide may be employed. If carbamate is employed as an oxidant nitrogen source, the resultant β-hydoxycarbamate is deprotected to yield the corresponding β-hydroxyamine. If sulfonamide is employed as an oxidant nitrogen source, the resultant β-hydroxysulfonamide is deprotected to yield the corresponding β-hydroxyamine. The resultant β-hydroxyamine is then selectively oxidized in a second synthetic step to produce the desired D- and L- α-amino acid or D- and L-α-amino aldehyde.

专利号:WO-2012152438-A1
优先权日:2011-05-11
标题 :Process for the preparation of nitrate acid ester of organic compounds
发明人：BONFANTI ANNALISA; STORONI LAURA; RONSIN GAEL
权利人:NICOX SA; BONFANTI ANNALISA; STORONI LAURA; RONSIN GAEL
摘要:The present invention relates to a one-step process for the synthesis of nitric acid esters or 15 N isotopically labeled nitrate esters of organic compounds starting from the correspondent alcohols. Formula (I).