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CAS号34921-76-1 N1-(4-氰基-2-乙基苯基)乙酰胺 | CAS号103796-17-4 4-acetylamino-3... | CAS号33098-65-6 2-乙基乙酰苯胺 | CAS号105902-59-8 acetic acid-(4-... | CAS号51688-73-4 4-溴-2-乙基乙酰苯胺乙酸-(4-乙酰基-2-乙基-苯胺)置于1,4-二氧六环,盐酸,Sodium Hypobromide体系中,化学反应生成 4-氨基-3-乙基苯甲酸
参考文献:The Alkaloids Of Tabernanthe Iboga. Vii.1 Derivatives Of Isoquinuclidine
标题:The Alkaloids Of Tabernanthe Iboga. Vii.1 Derivatives Of Isoquinuclidine
摘要:
DOI:10.1021/ja01544A038
海关参考信息
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2906210000-苄醇
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专利信息
专利号:US-2012165520-A1
优先权日:2010-12-23
标题:Process for the synthesis of prodrugs of opioids
发明人:MCGEE PAUL; GARNETT IAN; JUAN E; MANAGE A; CARNIAUX JEAN-FRANCOIS
权利人:MCGEE PAUL; GARNETT IAN; JUAN E; MANAGE A; CARNIAUX JEAN-FRANCOIS
摘要:The present invention provides a process for the synthesis of opioid prodrugs. In particular, the present invention provides a process for the synthesis of opioid prodrugs comprising: treating an opioid, in the form of a salt or a freebase, with a carbonyl synthon to form an activated intermediate and subsequently reacting the activated intermediate with an amine, in the form of a salt or a freebase.
专利号:US-8003785-B2
优先权日:2008-06-18
标 题 :Halo-substituted pyrimidodiazepines
发明人:CAI JIANPING; CHEN SHAOQING; CHU XIN-JIE; LUK KIN-CHUN; MISCHKE STEVEN GREGORY; SUN HONGMAO; WOVKULICH PETER MICHAEL
权利人:TAKEDA PHARMACEUTICAL
摘要:The present invention provides PLK1 inhibitor compounds of formula I: n nuseful in the treatment or control of cell proliferative disorders, particularly oncological disorders. These compounds and formulations containing such compounds may be useful in the treatment or control of solid tumors, such as, for example, breast, colon, lung and prostate tumors and other oncological diseases such as non-Hodgkin's lymphomas. Also provided are intermediate compounds useful in the synthesis of compounds of formula I.