CAS: 42340-98-7; 1-(1-Isocyanatoethyl)Naphthalene

上下游产品

carbamate(1R,2S,R)-trans-2-(Cyanomethyl)cyclohexyl N-1-(1-Naphthyl)-ethylcarbamate carbamate(1S,2R,R)-trans-2-(Cyanomethyl)cyclohexyl N-1-(1-Naphthyl)-ethylcarbamate carbamate(1R,2S,R)-trans-2-(2-Cyanoethyl)cyclopentyl N-1-(1-Naphthyl)ethylcarbamate carbamate(1S,2R,R)-trans-2-(2-Cyanoethyl)cyclopentyl N-1-(1-Naphthyl)ethylcarbamate ((R)-1-Naphthalen-1-yl-ethyl)-carbamic acid (R)-2,2,2-trifluoro-1-p-tolyl-ethyl ester ((R)-1-Naphthalen-1-yl-ethyl)-carbamic acid (R)-1-phenylsulfanylmethyl-propyl ester ((R)-1-Naphthalen-1-yl-ethyl)-carbamic acid (S)-1-phenylsulfanylmethyl-propyl ester ((R)-1-Naphthalen-1-yl-ethyl)-carbamic acid (R)-1-methyl-2-phenylsulfanyl-propyl ester

📜(S,R)-1-Ethynyloctyl N-<1-(-Naphthyl)Ethyl>Carbamate置于三氯硅烷,三乙胺体系中,用 二氯甲烷 作为反应溶剂,化学反应生成 (R)-(-)-1-萘乙基异氰酸酯,(-)-(S)-癸-1-炔-3-醇
参考文献:Synthesis Of 1,2,3-Decanetriol Stereoisomers
标题:Synthesis Of 1,2,3-Decanetriol Stereoisomers
摘要:
DOI:10.1021/jo01310A017

专利信息

专利号:WO-9102739-A1
优先权日:1989-08-11
标题:Synthesis of glycosides having predetermined stereochemistry
发明人：DANISHEFSKY SAMUEL J
权利人:UNIV YALE
摘要:Methods of stereoselectively preparing a substituted 1,2-anhydrosugar wherein a substituted glycal is converted into a 1,2-anhydrosugar that is utilized to glycosylate a hydroxyl group containing glycal, are disclosed. Methods of preparing a saccharide multimer wherein a nucleophile is reacted with a substituted 1,2-anhydrosugar having a plurality of non-participating substituents, are disclosed. In addition, methods of preparing stereospecific halo-substituted saccharide multimers by haloglycosylation of a glycosyl donor substituted glycal and a glycosyl acceptor glycal derivative in the absence of water and in the presence of a halonium ion, are disclosed. Methods of preparing stereospecific particle-linked halo-substituted saccharide multimers, by haloglycosylation of a particle-linked nucleophilic hydroxyl group with a substituted glycal and a halonium ion, are also disclosed.

专利号:US-2005192265-A1
优先权日:2003-03-20
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-6906056-B2
优先权日:1998-06-22
标 题:Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THOMPSON RICHARD C; WILKIE STEPHEN; STACK DOUGLAS R; VANMETER ELDON E; SHI QING; BRITTON THOMAS C; AUDIA JAMES E; REEL JON K; MABRY THOMAS E; DRESSMAN BRUCE A; CWI CYNTHIA L; HENRY STEVEN S; MCDANIEL STACEY L; STUCKY RUSSELL D; PORTER WARREN J
权利人:LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.

专利号:US-4260633-A
优先权日:1980-04-21
标题:Pesticidal esters of amino acids
发明人：ANDERSON RICHARD J; ADAMS KAREN G; HENRICK CLIVE A
权利人:ZOECON CORP
摘要:Novel diastereomeric esters of amino acids, novel intermediates therefor, synthesis thereof, and the use of said esters for the control of pests.

专利号:US-4259348-A
优先权日:1980-05-02
标题 :Pesticidal esters of amino acids
发明人：ANDERSON RICHARD J
权利人:ZOECON CORP
摘要:A novel diastereomeric ester of an amino acid, synthesis thereof, and the use of said ester for the control of pests.

专利号:EP-1836163-B1
优先权日:2004-12-23
标题 :Pyrrolidine derivatives for the treatment of a disease depending on the activity of renin
发明人：BREITENSTEIN WERNER; COTTENS SYLVAIN; EHRHARDT CLAUS; JACOBY EDGAR; LORTHIOIS EDWIGE LILIANE JEANNE; MAIBAUM JUERGEN KLAUS; OSTERMANN NILS; SELLNER HOLGER; SIMIC OLIVER
权利人:NOVARTIS AG
摘要:Novel 3-mono-, 3,4-di- and 3,4,4,-tri-substituted pyrrolidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on inappropriate activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on inappropriate activity of renin; the use of a compound of that class in the treatment of a disease that depends on inappropriate activity of renin; pharmaceutical formulations comprising a said substituted pyrrolidine compound, and/or a method of treatment comprising administering a said substituted pyrrolidine compound, a method for the manufacture of said substituted pyrrolidine compounds, and novel intermediates and partial steps for their synthesis are described. The substituted pyrrolidine compounds are especially of the formula I wherein the substituents are as described in the specification.