CAS: 15968-05-5; 2,2',6,6'-Tetrachloro-1,1'-Biphenyl
该化合物是一种属于多氯联苯类的氯化联苯化合物,其特征是联苯结构中存在4个氯原子,特别是在2,2',6和6'的方位上.该化合物在室内温度下一般没有色素,不光黄色固体,在水中溶解,但在有机溶剂中可溶解.由于其化学稳定性和疏水性,在各种工业应用中使用了2,2,6,6,6欧元-四氯联苯,包括电容器和变压器中的电流.然而,与其他多氯联苯一样,它因其环境持久性和潜在毒性而得到承认,导致食物链中的生物累积,对人体和野生动物造成不良的健康影响.许多国家已经实施了管制措施,以限制其使用和管理其环境影响.
- 相似结构搜索
- 产品信息参考
;;;; - InChIKey: PXAGFNRKXSYIHU-UHFFFAOYSA-N
- 1S/C12H6Cl4/c13-7-3-1-4-8(14)11(7)12-9(15)5-2-6-10(12)16/h1-6H
- 计算化学: 氢键受体数*氢键供体数*可旋转键数1.0
相似化合物
33146-45-1 33979-03-2 56558-16-8物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS08 & GHS09;
注释: Health hazard & Environment - 危险类别特定目标器官毒性-重复接触 类别2
水生急性毒性 类别1
水生慢性毒性 类别1 - 警示词Warning(警告)
- 危险描述H373 |长期或反复接触可能损害器官.
H400 |对水生生物毒性极大.
H410 |对水生生物毒性极大并具有长期持续影响. - 防范说明P260-P273-P391-P501
- 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
欧盟法规
C&L通报上下游产品
2,6,2',6'-tetrachloro-benzidine 1,3-dichloro-2-iodobenzene 2,6-Dichloroaniline 3,5-dichloro-1-nitrobenzene 2,2',3,3',5,5',6,6'-°Ctachlorobiphenyl 2,2',3,3',6,6'-hexachlorobiphenyl 2,2',3,6,6'-Pentachlorobiphenyl 2,2',3,3',5,6,6'-heptachlorobiphenyl合成工艺路线路线简述
📜1,3-二氯苯置于正丁基锂,二异丙胺,Copper(L) Cyanide,Lithium Chloride,对苯醌体系中,用 四氢呋喃 用作溶剂,化学反应 3.5H,以52%的收率获得2,2',6,6'-四氯联苯
参考文献:Asymmetric Bromine-lithium Exchange: On The Importance Of Both The Diamine Ligand And The Organolithium Reagent
标题:Asymmetric Bromine-lithium Exchange: On The Importance Of Both The Diamine Ligand And The Organolithium Reagent
摘要:对一系列具有手性前体的联苯进行了不对称溴-锂交换的研究.
Doi:10.1039/c5Cc06548H
海关参考信息
- 2903919090-氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1016/j.chemosphere.2006.04.043
摘要:Saalfield SL, Wnuk JD, Murray MM, Dunnivant FM. A comparison of two techniques for studying sediment desorption kinetics of hydrophobic pollutants. Chemosphere. 2007 Jan;66(2):384–9. doi: 10.1016/j.chemosphere.2006.04.043.
参考文献:10.1021/jm00155a010
摘要:Rickenbacher U, McKinney JD, Oatley SJ, Blake CC. Structurally specific binding of halogenated biphenyls to thyroxine transport protein. J Med Chem. 1986 May;29(5):641–8. doi: 10.1021/jm00155a010.
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