CAS: 1501-27-5; 5-Methoxy-5-Oxopentanoic Acid

相似化合物

4221-03-8 54322-10-0 818-38-2

上下游产品

CAS号1119-40-0 戊二酸二甲酯 | CAS号67-56-1 甲醇 | CAS号108-55-4 戌二酸酐 | CAS号110-94-1 戊二酸 | CAS号18107-18-1 (三甲硅烷)重氮甲烷 | CAS号124-41-4 甲醇钠 | CAS号14273-92-8 5-羟基戊酸甲酯 | CAS号6654-36-0 6-氧代己酸甲酯 | CAS号6581-66-4 2-甲氧基四氢吡喃 | CAS号186581-53-3 重氮甲烷 | CAS号3637-14-7 5-羰基辛酸 | CAS号35444-44-1 甲基脂肪酰氯 | CAS号1732-09-8 辛二酸二甲酯 | CAS号73087-76-0 6-Methyltetraco... | CAS号73087-77-1 19,22-Dimethylt... | CAS号83483-72-1 (S)-24-Hydroxy-... | CAS号120167-87-5 N,N'-butanediyl... | CAS号120167-86-4 methyl 6-(N-phe... | CAS号7560-61-4 1-methylsulfony... | CAS号120167-96-6 nC12H25N(SO2Me)...

戊二酸二甲酯置于sodium Hydroxide,Phosphate Buffer体系中,化学反应生成戊二酸单甲酯
参考文献:Enzymatic Preparation Of Alkanedicarboxylic Acid Monoesters
标题:Enzymatic Preparation Of Alkanedicarboxylic Acid Monoesters
摘要:使用假单胞菌 Mr-2068 的酯酶水解烷基二羧酸二甲酯,只能得到纯净的单酯.水解活性取决于底物的碳链长度.这种酯酶还能催化α-甲基烷二羧酸二甲酯的对映和区域选择性水解.
Doi:10.1246/cl.1995.539

专利信息

专利号:US-7109377-B2
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
发明人：SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
权利人:HARVARD COLLEGE
摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

专利号:US-2024400608-A1
优先权日:2021-09-03
标题:Synthesis of bicycle toxin conjugates, and intermediates thereof
发明人：WITTY DAVID; LIMB DARREN; MIN BYOUNG JOON; HE LIWEN; SANDERS WILLIAM J; NNANABU ERNEST OBINNA
权利人:BRICYCLETX LTD
摘要:The present invention relates to Bicycle toxin conjugates, methods for preparation, and methods of use for treating cancer.

专利号:US-11225655-B2
优先权日:2010-04-16
标题:Bi-functional complexes and methods for making and using such complexes
发明人：GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.

专利号:US-2003082830-A1
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products

专利号:WO-2023031623-A2
优先权日:2021-09-03
标 题 :Synthesis of bicycle toxin conjugates, and intermediates thereof

专利号:WO-0006525-A9
优先权日:1998-07-25
标题:Synthesis of combinatorial libraries of compounds reminiscent of natural products