专利号:US-12161637-B2 优先权日:2022-09-30 标题 :Anti-cancer gold complex, process of synthesis and method of treatment thereof 发明人:KHAN HASEEB AHMAD; ALHOMIDA ABDULLAH SALEH; AL-HOSHANI ALI; ISAB ANVARHUSEIN ABDULKADIR 权利人:UNIV KING SAUD 摘要:The present disclosure relates generally to anti-cancer pharmaceuticals. More specifically, the disclosure is directed to gold complexes of Formula I with anti-cancer properties. The disclosure also provides a pharmaceutical composition comprising the complexes, a process of synthesizing the complexes and a method of treating cancer. The complexes of the present disclosure have a multi-target approach to cancer therapeutics by inducing cell apoptosis, cytotoxicity, mitochondrial membrane potential depolarization and increasing reactive oxygen species in cancer cells.
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专利号:US-2023087073-A1 优先权日:2022-09-30 标题 :Anti-cancer gold complex, process of synthesis and method of treatment thereof
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参考文献:10.1007/s11947-024-03640-5 摘要:Chang Y, Lin H, Song Z, Liu Y, Xiao X, Wei B, Fan R. Developing a Molecular Imprinting Sensor Based on Double-Layer Coating Structure for the Rapid and Sensitive Detection of Chlortetracycline in Milk. Food Bioprocess Technol. 2024 Oct 23;18(3):2795–805. doi: 10.1007/s11947-024-03640-5.