CAS: 82958-44-9; ((2R,3S,4S,4Ar,10Bs)-3,4,8,10-Tetrahydroxy-9-Methoxy-6-Oxo-2,3,4,4A,6,10B-Hexahydropyrano[3,2-C]Isochromen-2-yl)Methyl 3,4,5-Trihydroxybenzoate
该化合物是属于酚类化合物的一种化学化合物,特别是贝格宁的加仑衍生物,其特点是结构复杂,包括一个附于贝格宁骨柱的加仑基组,该化合物以潜在的生物活动而著称,包括抗氧化剂,抗炎和抗微生物特性,使其对药理研究感兴趣;其结构中存在氢氧基化合物,有助于其再活动,并能够与各种生物目标互动;此外,11-O-Galloyrbergenin与其他植物化学品结合,可产生协同效应,增强治疗潜力;其溶性和稳定性可因溶剂和环境条件而异,这些条件在天然产品化学和药剂的应用中是需要考虑的重要因素;
- 英文名称((2R,3S,4S,4Ar,10Bs)-3,4,8,10-Tetrahydroxy-9-Methoxy-6-Oxo-2,3,4,4A,6,10B-Hexahydropyrano[3,2-C]Isochromen-2-yl)Methyl 3,4,5-Trihydroxybenzoate
- 中文名称11-O-没食子酰岩白菜素
- IUPAC名称((2R,3S,4S,4aR,10bS)-3,4,8,10-tetrahydroxy-9-methoxy-6-oxo-2,3,4,4a,6,10b-hexahydropyrano[3,2-c]isochromen-2-yl)methyl 3,4,5-trihydroxybenzoate
- 其它别名11-O-Galloylbergenin; Benzoic Acid, 3,4,5-Trihydroxy-, [(2R,3S,4S,4Ar,10Bs)-2,3,4,4A,6,10B-Hexahydro-3,4,8,10-Tetrahydroxy-9-Methoxy-6-Oxopyrano[3,2-C][2]Benzopyran-2-Yl]Methyl Ester; 11 O Galloylbergenin,11Ogalloylbergenin; Pyrano[3,2-C][2]Benzopyran,Benzoic Acid Deriv.; 11-O-Galloylbergenin, 10 Mm In Dmso
- CAS编号82958-44-9
- MFCD编号:MFCD22375465
- 分子式:C21H20O13分子量:480.38
- 产品CID: 1819298
- 产品分类天然产物 → 酚类
物理性质
MSDS等安全信息
上下游产品
CAS号149-91-7 没食子酸; 3,4,5-三羟基苯甲酸 | CAS号477-90-7 岩白菜素 | CAS号1916-07-0 3,4,5-三甲氧基苯甲酸甲酯 | CAS号33815-57-5 二-O-甲基岩白菜素合成工艺路线路线简述
📜岩白菜素置于吡啶,4-二甲氨基吡啶,Palladium On Carbon,氢气,Potassium Carbonate体系中,用 乙醇,二氯甲烷,N,N-二甲基甲酰胺,丙酮 作为反应溶剂,化学反应生成 11-O-没食子酰岩白菜素
参考文献:Synthesis And Antiglycation Potentials Of Bergenin Derivatives
标题:Synthesis And Antiglycation Potentials Of Bergenin Derivatives
摘要:Bergenin (1),Major Bioactive Compound Isolated From Methanolic Extract Of Mallotus Philippinensis,Displayed Moderate Age Inhibition Activity (Ic50 = 186.73 Mu M). A Series Of Derivatives Of Bergenin (3A-K) Containing Variety Of Aromatic Acids Were Synthesized Under Mild Conditions By Modification Of Sugar Part. Selective Esterification Of Hydroxyl Groups On The Sugar Part Enhanced Antiglycation Potential Of Bergenin. Compounds 3J And 3K Exhibited Potent Antiglycation Activity With The Ic50 Values Of 60.75 And 12.28 Mu M,Respectively. (C) 2011 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Bmcl.2011.04.131
海关参考信息
- 2902600000-乙苯
2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1016/j.bmcl.2011.04.131
摘要:Vijaya Kumar T, Tiwari AK, Robinson A, Suresh Babu K, Sateesh Chandra Kumar R, Anand Kumar D, Zehra A, Madhusudna Rao J. Synthesis and antiglycation potentials of bergenin derivatives. Bioorganic & Medicinal Chemistry Letters. 2011 Aug;21(16):4928–31. doi: 10.1016/j.bmcl.2011.04.131.
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