CAS: 741253-05-4; (1H-Indol-3-yl)Boronic Acid

专利信息

专利号:US-9346851-B2
优先权日:2008-02-22
标 题 :Chemical modification of proteins
发明人：BERNARDES GONCALO; CHALKER JUSTIN; DAVIS BENJAMIN
权利人:BERNARDES GONCALO; CHALKER JUSTIN; DAVIS BENJAMIN; RP SCHERER TECHNOLOGIES LLC
摘要:The invention relates to methods for selectively converting a cysteine residue in a peptide or protein to the dehydroalanine (Dha) residue. The method also works on selenocysteine and substituted cysteine and selenocysteine residues, resulting in the Dha residue which may be converted to any natural or unnatural amino acid residue desired without the alteration of the remainder of the peptide or protein. The invention also allows ligation of a desired peptide at any point rather than at a point where there should be a naturally occurring cysteine, thereby allowing native chemical ligation to be used in the synthesis of peptides that do not contain cysteine. The methodology allows for the synthesis of very large peptides.

专利号:US-7960589-B2
优先权日:2006-09-06
标 题:Synthesis of sphingosines and their derivatives
发明人：YANG HAO; LIEBESKIND LANNY S
权利人:UNIV EMORY
摘要:Embodiments of the present disclosure provide for methods of making sphingosines and derivatives thereof, and the like.

专利号:US-2024262809-A1
优先权日:2021-04-27
标题:Method for preparing intermediate for synthesis of xanthine oxidase inhibitor

专利号:WO-2022231261-A1
优先权日:2021-04-27
标 题:Method for preparing intermediate for synthesis of xanthine oxidase inhibitor

专利号:US-2009227575-A1
优先权日:2008-03-04
标 题 :7H-PYRROLO[2,3-H]QUINAZOLINE COMPOUNDS, THEIR USE AS mTOR KINASE AND PI3 KINASE INHIBITORS, AND THEIR SYNTHESIS
发明人：VENKATESAN ARANAPAKAM MUDUMBAI; CHEN ZECHENG; DOS SANTOS OSVALDO; BROOIJMANS NATASJA; GOPALSAMY ARIAMALA
权利人:WYETH CORP
摘要:A 7H-pyrrolo[2,3-h]quinazoline compound of the formula I n n n n n n n n n n wherein Ar, R 1 , R 2 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , and n are as defined in the specification, and methods for making same.

专利号:CN-117242062-A
优先权日:2021-04-27
标题 :Preparation method for intermediates used in the synthesis of xanthine oxidase inhibitors