CAS: 6520-83-8; Ethyl 2-Methoxy-6-Methylbenzoate

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CAS号6555-40-4 6-甲基水杨酸乙酯 | CAS号77-78-1 硫酸二甲酯 | CAS号74-88-4 碘甲烷 | CAS号10544-63-5 巴豆酸乙酯 | CAS号2161-90-2 1-甲氧基-1,3-环己二烯 | CAS号220899-03-6 苯菌酮 | CAS号6555-40-4 6-甲基水杨酸乙酯 | CAS号65131-09-1 7-甲氧基-3-苯磺酰-1(3... | CAS号13185-18-7 8-甲氧基-1-萘满酮 | CAS号6161-65-5 2-甲氧基-6-甲基苯甲酸 | CAS号16611-84-0 Anacardic Acid | CAS号130662-48-5 4-bromo-7-metho... | CAS号103904-74-1 2-(14-hydroxype... | CAS号18362-36-2 2-羟基-6-甲基苯甲醛 | CAS号74794-52-8 1H-2-Benzopyran...

6-甲基水杨酸乙酯/2-羟基-6-甲基苯甲酸乙酯 反应生成 2-甲氧基-6-甲基苯甲酸乙酯
参考文献:Nogalamycin同源物的合成研究[4] 1,2合成和nogalamycin同源物的抗肿瘤活性
标题:Nogalamycin同源物的合成研究[4] 1,2合成和nogalamycin同源物的抗肿瘤活性
摘要:在我们的合成研究总过程中先前合成的或最初通过探索的合成方案生产的诺加霉素同系物的各种结构类型及其部分结构,均经过了体外细胞毒性和体内抗肿瘤活性的测定抵抗p388 Munne白血病.这些研究显然揭示了诺加霉素同类物的结构-活性关系的新颖方面.
DOI:10.1016/s0040-4020(01)81434-4

专利信息

专利号:CN-105131041-B
优先权日:2015-09-15
标 题 :A novel triphenyl organic bismuth (V) complex catalyst, its preparation method and its catalytic application in the synthesis of nitrogen-containing compounds

专利号:WO-9314086-A1
优先权日:1992-01-17
标 题 :Substituted 1-isoquinolone derivatives as angiotensin ii antagonists
发明人：FISHER LAWRENCE E; CAROON JOAN M; STABLER STEPHEN R; CLARK ROBIN D
权利人:SYNTEX INC
摘要:1-Isoquinolone derivatives and related compounds according to formula (I) wherein, Y is selected from the group consisting of H, OH, lower alkoxy, and halo; X is selected from the group consisting of H, lower alkyl acid, lower alkyl ester, and lower alkyl; and R1 is selected from the group consisting of H, alkenyl, lower alkyl, lower cycloalkyl, unsubstituted or substituted 3-spiro-1H-indane of structure (II) wherein R2 is H, OH, lower alkyl, lower alkoxy or halo, and 3-spiro-cycloalkyl of structure (III) wherein n is an integer from zero to six, provided that when R1 is spiro- X is H, or a pharmaceutically acceptable salt thereof, with the proviso that when R1 is spiro-, X is H, and when R1 is H, alkenyl, lower alkyl or lower cycloalkyl substituted at the 3-position of the isoquinolone moiety and X is H or lower alkyl, the (2'-1H--tetrazol-5-yl)biphenyl-4'-ylmethyl group cannot be at the 2(N) position, are useful as angiotensin II receptor antagonists. Also disclosed are methods of synthesis, intermediates, pharmaceutical formulations and methods of treatment.