CAS: 5610-49-1; 1-Butylpiperazine

相似化合物

412293-87-9 50866-75-6 4553-32-6

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CAS号110-85-0 哌嗪 | CAS号109-65-9 正溴丁烷 | CAS号2759-28-6 1-苄基哌嗪 | CAS号542-69-8 碘代正丁烷 | CAS号102-79-4 N-丁基二乙醇胺 | CAS号63981-41-9 4-Butyl-1-piper... | CAS号412293-87-9 1-B°C-4-丁基哌嗪 | CAS号21863-67-2 1-Piperazinecar... | CAS号7664-41-7 氨 | CAS号129791-91-9 3'-Hydroxy-5'-(...

📜4-Butyl-Piperazine-1-Carboxylic Acid Tert-Butyl Ester置于三氟乙酸体系中,化学反应 16.0H,反应生成 1-丁基哌嗪
参考文献:喹诺酮类抗生素对分枝杆菌的构效关系:在n-1和c-7处结构变化的影响.
标题:喹诺酮类抗生素对分枝杆菌的构效关系:在n-1和c-7处结构变化的影响.
摘要:对常规药物治疗有抵抗力的结核感染的再次出现表明需要针对结核分枝杆菌的替代化学疗法.作为优化针对结核分枝杆菌的喹诺酮类抗菌药物研究的一部分,我们准备了一系列n-1-和c-7取代的喹诺酮类化合物,以研究这两个位置上喹诺酮类修饰物与活性之间的特定结构-活性关系.对抗分枝杆菌.通过文献方法合成的化合物被评估了对福分枝杆菌和耻垢分枝杆菌以及革兰氏阴性和革兰氏阳性细菌的活性.化合物对堡垒分枝杆菌的活性用作结核分枝杆菌活性的晴雨表.
DOI:10.1021/jm9507082

专利信息

专利号:US-6534627-B1
优先权日:1989-10-23
标题:Synthesis and use of amino acid fluorides as peptide coupling reagents
发明人：CARPINO LOUIS A; EL-FAHAM AYMAN AHMED
权利人:RES CORP TECHNOLOGIES INC
摘要:The present invention is directed to the process of preparing a peptide comprising reacting a first amino acid or peptide with an amino acid fluoride of the formula: n or the acid fluoride salts thereof wherein n BLK is an N-amino protecting group; n AA is an amino acid residue; and n X is absent or a protecting group. n The amino acid fluoride is useful as a coupling agent in peptide synthesis.

专利号:US-4678784-A
优先权日:1984-04-11
标题 :Method for the treatment of LHRH diseases and conditions
发明人：HO CHIH Y
权利人:MCNEILAB INC
摘要:Fused tetracyclic benzodiazepines of the formula (I): (I) where R1 is a cyclic amine such as 1-piperazine and R2 is H or a substituent as defined herein are useful as LHRH antagonizing agents. Also, methods for their synthesis, intermediates used in such synthesis, methods for use as medicaments and pharmaceutical compositions are described.

专利号:US-9670145-B2
优先权日:2014-03-31
标题:Process for preparing 1,1-disubstituted ethylene monomers
发明人：TCHAPLINSKI VLADIMIR; GHERARDI STEFANO; DE LA FUENTE MOLINA VERÓNICA
权利人:AFINITICA TECH S L
摘要:The present invention relates to a process for preparing 1,1-disubstituted ethylene monomers having general formula (I) from a compound of general formula (II) and an active methylene compound of general formula (III) using a catalytic amount of an ammonium or iminium a salt in homogeneous phase or supported on a solid substrate. Said process allows the direct synthesis of the monomers and finds application in the preparation of a wide variety of monomers. The products obtained are reactive monomers of high purity which find application in the field of fast curing adhesives.

专利号:WO-2006079916-A1
优先权日:2005-01-26
标 题 :Thieno [2,3-d] pyrimidine compounds as inhibitors of adp-mediated platelets aggregation
发明人：ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; RAHMAN HAYAT; SCHWEITZER BARBARA ANN; TENBRINK RUTH ELIZABETH
权利人:PHARMACIA & UPJOHN CO LLC; ENNIS MICHAEL DALTON; KORTUM STEVEN WADE; RAHMAN HAYAT; SCHWEITZER BARBARA ANN; TENBRINK RUTH ELIZABETH
摘要:Compounds and pharmaceutically acceptable salts of the compounds are disclosed, wherein the compounds have the structure of Formula (I): wherein A1, A2, A3, A4, A5, A6, A7, A8, X4, X6, R2, R4, R5, and R6 are as defined in the detailed description of the invention. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.

专利号:US-2023357177-A1
优先权日:2020-12-17
标题:Synthesis of cannabidiol and analogs thereof, and related compounds, formulations, and methods of use

专利号:US-4547497-A
优先权日:1984-04-11
标 题:Amidine benzodiazepines, methods for their use and intermediates
发明人：HO CHIH Y
权利人:MCNEILAB INC
摘要:Fused tetracyclic benzodiazepines of the formula (I): ##STR1## where R 1 is an acyclic amine or cyclic amine such as 1-piperidine, 4-morpholine or 1-piperazine and R 2 is H or a substituent as defined herein as useful as antiallergins. Also, methods for their synthesis, intermediate used in such synthesis, methods for use as medicaments and pharmaceutical compositions.