CAS: 463-04-7; N-Pentyl Nitrite

上下游产品

CAS号71-41-0 正戊醇 | CAS号105827-78-9 吡虫啉 | CAS号109-66-0 正戊烷 | CAS号7782-77-6 亚硝酸 | CAS号75-18-3 二甲基硫 | CAS号56879-26-6 nitro hexaneper... | CAS号111029-14-2 3-nitro-2,4,5-t... | CAS号32818-79-4 戊烷-2,3-二酮 2-肟 | CAS号2197-01-5 3,3′-碘化二乙硫代花青 | CAS号71-41-0 正戊醇 | CAS号614-00-6 甲基苯基亚硝胺 | CAS号101-61-1 4,4'-四甲基二氨基二苯甲烷 | CAS号87412-86-0 1,3-二甲基-1,5-二氢-... | CAS号87412-62-2 1,3-dimethyl-4-... | CAS号87432-50-6 1,3-dimethyl-4-... | CAS号87-39-8 紫尿酸

戊醇置于硫酸,Sodium Nitrite体系中,用 水 作为反应溶剂,化学反应生成 亚硝酸正戊酯
参考文献:新混合的偶氮杯[4]芳烃酯衍生物的光谱和热性质
标题:新混合的偶氮杯[4]芳烃酯衍生物的光谱和热性质
摘要:的单-,二-,三-,和四-丙烯酰基酯对-Chloroazocalix [4]芳烃,其包括混合偶氮酯染料的第一实施例中通过用的钠盐丙烯酰氯反应合成对-Chloroazocalix [4]芳烃在惰性气氛下于四氢呋喃中溶解.的重氮盐p-Chloroaniline通过使用合成ñ-亚硝酸盐并在无水条件下与杯[4]芳烃偶联.这是首次用于合成偶氮杯[4]芳烃的重氮偶合反应.通过光谱方法表征的合成化合物表明,如果azocalix [4]芳烃包含至少一个游离酚基,则它们呈圆锥构象.这些化合物的结构已通过红外(ir),紫外-可见(uv-Vis),质子核磁共振(1 H NMR)和碳核磁共振(13 C NMR)进行了表征.使用差示热分析(dta),热重分析(tg)和导数热重分析(dtg)来确定化合物的热行为.
DOI:10.1016/j.Dyepig.2014.03.028

专利信息

专利号:US-11639349-B2
优先权日:2020-05-28
标题:Stereoselective synthesis of intermediate for preparation of heterocyclic compound
发明人：CHEN WEN-CHANG; HSU HAN-PEI; CHOU SHAN-YEN; CHUANG SHIH-CHIEH; YEN CHI-FENG
权利人:TAI GEN BIOTECHNOLOGY CO LTD; TAIGEN BIOPHARMACEUTICALS CO BEIJING LTD; TAIGEN BIOTECHNOLOGY CO LTD
摘要:Provided is a stereoselective synthesis of an intermediate for the preparation of the heterocyclic derivative as a Cap-dependent endonuclease inhibitor. The synthesis process has the advantages of simple operation, higher yield and relatively controllable steroselectivity, such that it is suitable for large-scale production.

专利号:US-7452994-B2
优先权日:2001-09-12
标 题 :Synthesis of enantiomerically pure amino-substituted fused bicyclic rings
发明人：MCEACHERN ERNEST J; BRIDGER GARY J; SKUPINSKA KRYSTYNA A; SKERLJ RENATO T; YANG WEN
权利人:ANORMED INC
摘要:This invention describes various processes for synthesis and resolution of racemic amino-substituted fused bicyclic ring systems. One process utilizes selective hydrogenation of an amino-substituted fused bicyclic aromatic ring system. An alternative process prepares the racemic amino-substituted fused bicyclic ring system via nitrosation. In addition, the present invention describes the enzymatic resolution of a racemic mixture to produce the (R)- and (S)-forms of amino-substituted fused bicyclic rings as well as a racemization process to recycle the unpreferred enantioner. Further provided by this invention is an asymmetric synthesis of the (R)- or (S)-enantiomer of primary amino-substituted fused bicyclic ring systems.

专利号:US-6177564-B1
优先权日:1998-09-11
标题:Process for the synthesis of N-benzyl-3-(4-fluorophenyl)-1-4-oxazin-2-one
发明人：NELSON TODD D; BHUPATHY MAHADEVAN
权利人:MERCK & CO INC
摘要:The present invention is concerned with a novel process for the preparation of N-benzyl-3-(4-fluorophenyl)-1,4-oxazin-2-one of the formula:This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity, in particular, as substance P (neurokinin-1) receptor antagonists.

专利号:US-6951932-B2
优先权日:2001-10-25
标 题:Synthesis of 2-aralkoxyadenosines and 2-alkoxyadenosines
发明人：MOORMAN ALLAN R
权利人:KING PHARMACEUTICALS RES & DEV
摘要:The invention provides new methods for synthesis of 2-aralkyloxyadenosines and 2-alkoxyadenosines. The invention is particularly useful for synthesis of 2-[2-(4-chlorophenyl)ethoxy]adenosine. Preferred methods of the invention include activating a guanosine compound followed by hydrolysis; alkylating the hydrolyzed compound with subsequent animation to provide a 2-aralkyloxyadenosine or a 2-alkoxyadenosine compound.

专利号:US-2008287407-A1
优先权日:2003-12-10
标题 :Nitric Oxide Releasing Pyruvate Compounds, Compositions and Methods of Use
发明人：GARVEY DAVID S; FANG XINQIN; KHANAPURE SUBHASH P; RANATUNGA RAMANI R; WEY SHIOW-JYI
权利人:NITROMED INC
摘要:The invention describes novel nitrosated and/or nitrosylated pyruvate compounds and pharmaceutically acceptable salts thereof, and novel compositions comprising at least one nitrosated and/or nitrosylated pyruvate compound, and, optionally, at least one compound that donates, transfers or releases nitric oxide, stimulates endogenous synthesis of nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor or is a substrate for nitric oxide synthase, and/or at least one therapeutic agent. The invention also provides novel compositions comprising at least one pyruvate compound and at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase and/or at least one therapeutic agent. The invention also provides novel kits comprising at least one pyruvate compound, that is optionally nitrosated and/or nitrosylated, and, optionally, at least one nitric oxide donor and/or at least one therapeutic agent. The invention also provides methods for treating diseases resulting from oxidative stress, diabetes, reperfusion injury following ischemia, preservation of tissues, organs, organ parts and/or limbs.

专利号:US-8012993-B2
优先权日:2006-12-28
标题 :Stable S-nitrosothiols, method of synthesis and use
发明人：MOLINER JOSE REPOLLES; COY FRANCISCO PUBILL; MANCINI MARISABEL MOURELLE; NIETO JUAN CARLOS DEL CASTILLO; LLORENTE LYDIA CABEZA; BONIN JUAN MARTINEZ; SALADRIGAS ANA MODOLELL
权利人:LACER SA
摘要:The present invention relates to stable S-nitrosothiols derivatives of formula (I) n nhaving vasodilating effect and which inhibit the aggregation of the platelets and which therefore are useful for the preparation of medicaments for treatment of NO related diseases. The invention also relates to a process for the synthesis of the compounds of formula (I).